The effect of overall treatment time of radiation therapy on local control of T1-stage squamous cell carcinoma of the glottis

1997 ◽  
Vol 55 (6) ◽  
pp. 652
Author(s):  
R Holloway
Keyword(s):  
Squamous Cell Carcinoma ◽  
Radiation Therapy ◽  
Cell Carcinoma ◽  
Local Control ◽  
Squamous Cell ◽  
Treatment Time ◽  
Overall Treatment Time ◽  
T1 Stage

Is Radiation Therapy a Preferred Alternative to Surgery for Squamous Cell Carcinoma of the Base of Tongue?

2000 ◽  
Vol 18 (1) ◽  
pp. 35-35 ◽  
Author(s):  
William M. Mendenhall ◽  
Scott P. Stringer ◽  
Robert J. Amdur ◽  
Russell W. Hinerman ◽  
Giselle J. Moore-Higgs ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Multivariate Analysis ◽  
Radiation Therapy ◽  
Cell Carcinoma ◽  
Local Control ◽  
Treatment Time ◽  
Overall Treatment Time ◽  
Regional Control ◽  
Base Of Tongue ◽  
Local Regional Control

PURPOSE: To evaluate irradiation alone for treatment of base-of-tongue cancer. PATIENTS AND METHODS: Two hundred seventeen patients with squamous cell carcinoma of the base of tongue were treated with radiation alone and had follow-up for ≥ 2 years. RESULTS: Local control rates at 5 years were as follows: T1, 96%; T2, 91%; T3, 81%; and T4, 38%. Multivariate analysis revealed that T stage (P = .0001) and overall treatment time (P = .0006) significantly influenced local control. The 5-year rates of local-regional control were as follows: I, 100%; II, 100%; III, 83%; IVA, 64%; and IVB, 65%. Multivariate analysis revealed that the following parameters significantly affect the probability of this end point: T stage (P = .0001), overall treatment time (P = .0001), overall stage (P = .0131), and addition of a neck dissection (P = .0021). The rates of absolute and cause-specific survival at 5 years were as follows: I, 50% and 100%; II, 81% and 100%; III, 65% and 76%; IVA, 42% and 56%; and IVB, 44% and 52%. Severe radiation complications developed in eight patients (4%). CONCLUSION: The likelihood of cure after external-beam irradiation was related to stage, overall treatment time, and addition of a planned neck dissection. The local-regional control rates and survival rates after radiation therapy were comparable to those after surgery, and the morbidity associated with irradiation was less.

Impact of overall treatment time of fractionated irradiation on local control of human FaDu squamous cell carcinoma in nude mice

1994 ◽  
Vol 32 (2) ◽  
pp. 137-143 ◽  
Author(s):  
Michael Baumann ◽  
Cordula Liertz ◽  
Heinz Baisch ◽  
Thomas Wiegel ◽  
Jörn Lorenzen ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Local Control ◽  
Squamous Cell ◽  
Nude Mice ◽  
Treatment Time ◽  
Fractionated Irradiation ◽  
Overall Treatment Time

The Effect of Overall Treatment Time of Radiation Therapy on Local Control of T1-Stage Squamous Call Carcinoma of the Glottis

1996 ◽  
Vol 106 (12) ◽  
pp. 1545-1547 ◽  
Author(s):  
Kazushige Hayakawa ◽  
Norio Mitsuhashi ◽  
Tetsuo Akimoto ◽  
Katsuya Maebayashi ◽  
Hitoshi Ishikawa ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Local Control ◽  
Treatment Time ◽  
Overall Treatment Time ◽  
T1 Stage

Early glottic squamous cell carcinoma: Predictive value of MR imaging for the rate of 5-year local control with radiation therapy

2000 ◽  
Vol 41 (1) ◽  
pp. 38-44 ◽  
Author(s):  
R. Murakami ◽  
Y. Baba ◽  
M. Furusawa ◽  
R. Nishimura ◽  
T. Nakaura ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Radiation Therapy ◽  
Mr Imaging ◽  
Cell Carcinoma ◽  
Local Control ◽  
Squamous Cell ◽  
Predictive Value
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