First-Line Inhaled Steroids for Pediatric Asthma Gain Support

Corticosteroids are the most potent inhaled anti-inflammatory drugs for asthma treatment. This paper reviews the clinical evidence supporting the early use of inhaled steroids in asthma as a first line treatment. Inhaled steroids can probably alter the course of asthma, especially in mild asthmatics. Once they have been shown to improve control of asthma and even if the need for beta2-agonists is virtually nil, their use should be continued at low doses (ie, equivalent to 400 to 500 μg of budesonide or beclomethasone) for at least one year before attempting to reduce the dosage.

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Addition of inhaled long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults

10.1002/14651858.cd005307 ◽

2004 ◽

Cited By ~ 26

Author(s):

Muireann Ni Chroinin ◽

Ilana IG Greenstone ◽

Francine Ducharme

Keyword(s):

Persistent Asthma ◽

First Line ◽

Inhaled Steroids ◽

First Line Therapy ◽

Line Therapy ◽

Long Acting

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Addition of long-acting beta2-agonists to inhaled steroids as first line therapy for persistent asthma in steroid-naive adults and children

Cochrane Database of Systematic Reviews ◽

10.1002/14651858.cd005307.pub2 ◽

2009 ◽

Cited By ~ 15

Author(s):

Muireann Ni Chroinin ◽

Ilana Greenstone ◽

Toby J Lasserson ◽

Francine M Ducharme

Keyword(s):

Persistent Asthma ◽

First Line ◽

Inhaled Steroids ◽

First Line Therapy ◽

Line Therapy ◽

Adults And Children ◽

Long Acting

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Steroids: First Line Treatment in Pediatrics

Canadian Respiratory Journal ◽

10.1155/1995/878063 ◽

1995 ◽

Vol 2 (suppl a) ◽

pp. 13A-18A

Author(s):

Sheldon Spier

Keyword(s):

Immune System ◽

Side Effects ◽

Bone Metabolism ◽

Adrenal Glands ◽

Line Treatment ◽

First Line ◽

Inhaled Steroids ◽

The Voice ◽

First Line Treatment ◽

Compliance Versus

The benefits derived from the use or inhaled steroids in pediatric asthma are reviewed in relation to the age of the patient, the delivery system and the compliance versus frequency of administration of these medications. Side effects are discussed with regard to the age or the child and the following systems: the eyes, the skin, the oropharynx, the voice, the immune system, lipid and carbohydrate metabolism, adrenal glands, bone metabolism and growth.

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