The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices

Maree T. Smith; Peter J. Cabot; Fraser B. Ross; Alan D. Robertson; Richard J. Lewis

doi:10.1016/s0304-3959(01)00436-5

The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices

Pain ◽

10.1016/s0304-3959(01)00436-5 ◽

2002 ◽

Vol 96 (1) ◽

pp. 119-127 ◽

Cited By ~ 123

Author(s):

Maree T. Smith ◽

Peter J. Cabot ◽

Fraser B. Ross ◽

Alan D. Robertson ◽

Richard J. Lewis

Keyword(s):

Spinal Cord ◽

Substance P ◽

Calcium Channel ◽

Calcium Channel Blocker ◽

Channel Blocker ◽

The Novel ◽

Rat Spinal Cord ◽

P Release ◽

Dose Dependent ◽

Substance P Release

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cAMP signaling through protein kinase A and Epac2 induces substance P release in the rat spinal cord

Neuropharmacology ◽

10.1016/j.neuropharm.2021.108533 ◽

2021 ◽

pp. 108533

Author(s):

Wenling Chen ◽

James A. McRoberts ◽

Helena S. Ennes ◽

Juan Carlos Marvizon

Keyword(s):

Spinal Cord ◽

Protein Kinase ◽

Substance P ◽

Protein Kinase A ◽

Camp Signaling ◽

Rat Spinal Cord ◽

P Release ◽

Substance P Release ◽

Kinase A

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Paclitaxel-induced peripheral neuropathy increases substance P release in rat spinal cord

European Journal of Pharmacology ◽

10.1016/j.ejphar.2015.11.055 ◽

2016 ◽

Vol 770 ◽

pp. 46-51 ◽

Cited By ~ 11

Author(s):

Terumasa Chiba ◽

Yusuke Oka ◽

Toshie Kambe ◽

Naoya Koizumi ◽

Kenji Abe ◽

...

Keyword(s):

Spinal Cord ◽

Peripheral Neuropathy ◽

Substance P ◽

Rat Spinal Cord ◽

P Release ◽

Substance P Release

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Cannabinoid CB1 receptor facilitation of substance P release in the rat spinal cord, measured as neurokinin 1 receptor internalization

European Journal of Neuroscience ◽

10.1111/j.1460-9568.2009.07075.x ◽

2010 ◽

Vol 31 (2) ◽

pp. 225-237 ◽

Cited By ~ 20

Author(s):

Guohua Zhang ◽

Wenling Chen ◽

Lijun Lao ◽

Juan Carlos G. Marvizón

Keyword(s):

Spinal Cord ◽

Substance P ◽

Cb1 Receptor ◽

Receptor Internalization ◽

Cannabinoid Cb1 Receptor ◽

Rat Spinal Cord ◽

Neurokinin 1 Receptor ◽

P Release ◽

Neurokinin 1 ◽

Substance P Release

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Relationship between capsaicin-evoked substance p release and neurokinin 1 receptor internalization in the rat spinal cord

Neuroscience ◽

10.1016/s0306-4522(02)00977-6 ◽

2003 ◽

Vol 118 (2) ◽

pp. 535-545 ◽

Cited By ~ 51

Author(s):

J.C.G. Marvizón ◽

X. Wang ◽

Y. Matsuka ◽

J.K. Neubert ◽

I. Spigelman

Keyword(s):

Spinal Cord ◽

Substance P ◽

Receptor Internalization ◽

Rat Spinal Cord ◽

Neurokinin 1 Receptor ◽

P Release ◽

Neurokinin 1 ◽

Substance P Release

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Intradermal injection of capsaicin induces acute substance P release from rat spinal cord dorsal horn

Neuroscience Letters ◽

10.1016/j.neulet.2006.09.072 ◽

2006 ◽

Vol 410 (3) ◽

pp. 183-186 ◽

Cited By ~ 11

Author(s):

Jing-Yin Yan ◽

Rui-Qing Sun ◽

Michael G. Hughes ◽

David J. McAdoo ◽

William D. Willis

Keyword(s):

Spinal Cord ◽

Substance P ◽

Dorsal Horn ◽

Intradermal Injection ◽

Spinal Cord Dorsal Horn ◽

Rat Spinal Cord ◽

P Release ◽

Spinal Cord Dorsal ◽

Substance P Release

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Neonatal capsaicin treatment abolishes the modulations by opioids of substance P release from rat spinal cord slices

Neuroscience Letters ◽

10.1016/0304-3940(89)90250-4 ◽

1989 ◽

Vol 96 (1) ◽

pp. 102-107 ◽

Cited By ~ 39

Author(s):

Michel Pohl ◽

Annie Mauborgne ◽

Sylvie Bourgoin ◽

Jean Jacques Benoliel ◽

Michel Hamon ◽

...

Keyword(s):

Spinal Cord ◽

Substance P ◽

Rat Spinal Cord ◽

P Release ◽

Substance P Release

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Src family kinases mediate the inhibition of substance P release in the rat spinal cord by μ-opioid receptors and GABAB receptors, but not α2 adrenergic receptors

European Journal of Neuroscience ◽

10.1111/j.1460-9568.2010.07335.x ◽

2010 ◽

Vol 32 (6) ◽

pp. 963-973 ◽

Cited By ~ 17

Author(s):

Guohua Zhang ◽

Wenling Chen ◽

Juan Carlos G. Marvizón

Keyword(s):

Spinal Cord ◽

Substance P ◽

Opioid Receptors ◽

Adrenergic Receptors ◽

Src Family Kinases ◽

Gabab Receptors ◽

Rat Spinal Cord ◽

P Release ◽

Substance P Release ◽

Μ Opioid Receptors

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Nitric Oxide Regulates Substance P Release from Rat Spinal Cord Synaptosomes

Journal of Neurochemistry ◽

10.1046/j.1471-4159.1995.65052050.x ◽

2002 ◽

Vol 65 (5) ◽

pp. 2050-2056 ◽

Cited By ~ 12

Author(s):

Yoshinori Kamisaki ◽

Kentaro Nakamoto ◽

Kouichirou Wada ◽

Tadao Itoh

Keyword(s):

Nitric Oxide ◽

Spinal Cord ◽

Substance P ◽

Rat Spinal Cord ◽

P Release ◽

Substance P Release

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NMDA receptors in primary afferents require phosphorylation by Src family kinases to induce substance P release in the rat spinal cord

Neuroscience ◽

10.1016/j.neuroscience.2010.01.009 ◽

2010 ◽

Vol 166 (3) ◽

pp. 924-934 ◽

Cited By ~ 18

Author(s):

W. Chen ◽

G. Zhang ◽

J.C.G. Marvizón

Keyword(s):

Spinal Cord ◽

Substance P ◽

Nmda Receptors ◽

Primary Afferents ◽

Src Family Kinases ◽

Rat Spinal Cord ◽

P Release ◽

Substance P Release

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Dual mechanisms for the facilitation of substance P release through serotonin3 receptor in rat spinal cord dorsal horn.

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)50201-3 ◽

1994 ◽

Vol 64 ◽

pp. 140

Author(s):

Takashi Hashimoto ◽

Atsuko Inoue ◽

Hiroaki Nishio ◽

Yoshihiro Nakata

Keyword(s):

Spinal Cord ◽

Substance P ◽

Dorsal Horn ◽

Spinal Cord Dorsal Horn ◽

Rat Spinal Cord ◽

P Release ◽

Spinal Cord Dorsal ◽

Substance P Release

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