Role of Nitric Oxide and Prostaglandin in the Protective Effect of Pibutidine Hydrochloride, a Novel Histamine H2-Receptor Antagonist, on the Gastric Mucosal Lesions in Rats

General Pharmacology The Vascular System ◽

10.1016/s0306-3623(97)00444-8 ◽

1998 ◽

Vol 31 (2) ◽

pp. 271-275 ◽

Author(s):

Y. Kiuchi ◽

Y. Isobe ◽

H. Kijima ◽

T. Saitoh ◽

S. Higuchi

Keyword(s):

Nitric Oxide ◽

Protective Effect ◽

Receptor Antagonist ◽

H2 Receptor Antagonist ◽

Gastric Mucosal Lesions ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Mucosal Lesions ◽

Histamine H2 Receptor Antagonist

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Protective effect of pibutidine hydrochloride, a novel histamine H2-receptor antagonist, on the gastric mucosal lesions in rats

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)41282-1 ◽

1998 ◽

Vol 76 ◽

pp. 293

Author(s):

Yoichi Kiuchi ◽

Yoshihiko Isobe ◽

Haruko Kijima ◽

Takashi Saito ◽

Shohei Higuchi

Keyword(s):

Protective Effect ◽

Receptor Antagonist ◽

H2 Receptor Antagonist ◽

Gastric Mucosal Lesions ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Mucosal Lesions ◽

Histamine H2 Receptor Antagonist

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Effect of lafutidine, a novel histamine H2‐receptor antagonist, on monochloramine‐induced gastric lesions in rats: Role of capsaicin‐sensitive sensory neurons

Journal of Gastroenterology and Hepatology ◽

10.1046/j.1440-1746.1999.01976.x ◽

1999 ◽

Vol 14 (9) ◽

pp. 859-865 ◽

Author(s):

Masakazu Umeda ◽

Akinobu Fujita ◽

Hideyuki Nishiwaki ◽

Koji Takeuchi

Keyword(s):

Receptor Antagonist ◽

Sensory Neurons ◽

Gastric Lesions ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Effect of laftidine, a histamine H2-receptor antagonist, on indomethacin-induced small intestinal lesions in rats: Role of capsaicin-sensitive neurons (CSN)

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)48477-1 ◽

2000 ◽

Vol 82 ◽

pp. 254

Author(s):

H. Mizoguchi ◽

Y. Ogawa ◽

A. Tanaka ◽

T. Kunikata ◽

S. Kato ◽

...

Keyword(s):

Receptor Antagonist ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Intestinal Lesions ◽

Small Intestinal ◽

Histamine H2 Receptor Antagonist

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Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on acid reflux esophagitis in rats through capsaicin-sensitive afferent neurons

Gastroenterology ◽

10.1016/s0016-5085(03)82268-0 ◽

2003 ◽

Vol 124 (4) ◽

pp. A449 ◽

Author(s):

Kenji Nagahama ◽

Shinichi Kato ◽

Masanori Yamato ◽

Koji Takeuchi

Keyword(s):

Protective Effect ◽

Receptor Antagonist ◽

Reflux Esophagitis ◽

Acid Reflux ◽

Afferent Neurons ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Protective effect of lafutidine, a histamine H2 receptor antagonist, against loxoprofen-induced small intestinal lesions in rats

Journal of Gastroenterology and Hepatology ◽

10.1111/j.1440-1746.2010.06223.x ◽

2010 ◽

Vol 25 ◽

pp. S111-S118 ◽

Author(s):

Kikuko Amagase ◽

Akimu Ochi ◽

Tetsuya Sugihara ◽

Shinichi Kato ◽

Koji Takeuchi

Keyword(s):

Protective Effect ◽

Receptor Antagonist ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Intestinal Lesions ◽

Small Intestinal ◽

Histamine H2 Receptor Antagonist

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Protective effect of histamine H2 receptor antagonist ranitidine against rotenone-induced apoptosis

NeuroToxicology ◽

10.1016/j.neuro.2009.08.005 ◽

2009 ◽

Vol 30 (6) ◽

pp. 1114-1119 ◽

Author(s):

Hae Jeong Park ◽

Hak Jae Kim ◽

Hyun-Kyung Park ◽

Joo-Ho Chung

Keyword(s):

Protective Effect ◽

Receptor Antagonist ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Induced Apoptosis ◽

Histamine H2 Receptor Antagonist

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Role of lipid peroxidation and neutrophil accumulation in the gastric mucosal injury induced by aspirin-HCl in rats Effect of roxatidine, a histamine H2 receptor antagonist with antioxidative properties

Pathophysiology ◽

10.1016/0928-4680(95)00010-x ◽

1995 ◽

Vol 2 (1) ◽

pp. 1-8 ◽

Author(s):

Yuji Naito ◽

Toshikazu Yoshikawa ◽

Kiichi Matsuyama ◽

Nobuaki Yagi ◽

Masahiro Arai ◽

...

Keyword(s):

Lipid Peroxidation ◽

Receptor Antagonist ◽

Mucosal Injury ◽

Neutrophil Accumulation ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Antioxidative Properties ◽

Histamine H2 Receptor Antagonist

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Protective Effect of Lafutidine, a Novel Histamine H2-Receptor Antagonist, on Dextran Sulfate Sodium-Induced Colonic Inflammation Through Capsaicin-Sensitive Afferent Neurons in Rats

Digestive Diseases and Sciences ◽

10.1023/b:ddas.0000043389.96490.76 ◽

2004 ◽

Vol 49 (10) ◽

pp. 1696-1704 ◽

Author(s):

Mitsuaki Okayama ◽

Ryoichi Tsubouchi ◽

Shinichi Kato ◽

Koji Takeuchi

Keyword(s):

Protective Effect ◽

Receptor Antagonist ◽

Dextran Sulfate ◽

Dextran Sulfate Sodium ◽

Afferent Neurons ◽

H2 Receptor Antagonist ◽

Colonic Inflammation ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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The novel histamine H2 receptor antagonist FRG-8813 prevents delay of wound repair induced by hydrogen peroxide in a rabbit gastric epithelial cell system

Journal of Gastroenterology and Hepatology ◽

10.1046/j.1440-1746.1998.01735.x ◽

1998 ◽

Vol 13 (11-s4) ◽

pp. S209-S213

Author(s):

NOBUHIRO SATO ◽

SUMIO WATANABE ◽

XIAN-EN WANG ◽

TARO OSADA ◽

HIROSHI TANAKA ◽

...

Keyword(s):

Hydrogen Peroxide ◽

Epithelial Cell ◽

Receptor Antagonist ◽

Wound Repair ◽

Cell System ◽

The Novel ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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Unique Profile of Lafutidine, A Novel Histamine H2-Receptor Antagonist - Mucosal Protection Throughout Gastrointestinal Tract Mediated by Capsaicin-Sensitive Afferent Neurons -

Drug Design Reviews - Online ◽

10.2174/1567269043480681 ◽

2004 ◽

Vol 1 (2) ◽

pp. 133-144 ◽

Author(s):

Sadayoshi Onodera ◽

Kayoko Nishida ◽

Koji Takeuchi

Keyword(s):

Gastrointestinal Tract ◽

Receptor Antagonist ◽

Mucosal Protection ◽

Afferent Neurons ◽

H2 Receptor Antagonist ◽

Histamine H2 Receptor ◽

H2 Receptor ◽

Histamine H2 Receptor Antagonist

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