Photosafety evaluation during drug development - how to use safety margins in support of human risk assessment

Toxicology Letters ◽

10.1016/s0378-4274(21)00742-6 ◽

2021 ◽

Vol 350 ◽

pp. S216

Author(s):

D. Bauer ◽

J. Schümann ◽

P. Ulrich ◽

B. Kittel ◽

H.-J. Martus

Keyword(s):

Risk Assessment ◽

Drug Development ◽

Human Risk Assessment ◽

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Atrazine and its metabolites (ATZs) in source water, finished water, and tap water from drinking water treatment plants and its human risk assessment in Zhoukou City, China

Human and Ecological Risk Assessment An International Journal ◽

10.1080/10807039.2021.1933896 ◽

2021 ◽

pp. 1-13

Author(s):

Yu Jian ◽

Xia Yunting ◽

Tian Xianghong ◽

Zhang Rong ◽

Bian Zhanqiang

Keyword(s):

Risk Assessment ◽

Drinking Water ◽

Water Treatment ◽

Tap Water ◽

Drinking Water Treatment ◽

Source Water ◽

Human Risk Assessment ◽

Water Treatment Plants

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Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Archives of Toxicology ◽

10.1007/s00204-021-03057-5 ◽

2021 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Human Risk Assessment ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment

Toxicology Letters ◽

10.1016/j.toxlet.2021.01.021 ◽

2021 ◽

Vol 341 ◽

pp. 94-106

Author(s):

Liliana Capinha ◽

Paul Jennings ◽

Jan N.M. Commandeur

Keyword(s):

Risk Assessment ◽

Species Differences ◽

Glutathione Transferases ◽

Glutathione Conjugates ◽

Human Risk Assessment ◽

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Mercury concentration in the sentinel fish species Orthopristis ruber: Effects of environmental and biological factors and human risk assessment

Marine Pollution Bulletin ◽

10.1016/j.marpolbul.2021.112508 ◽

2021 ◽

Vol 169 ◽

pp. 112508

Author(s):

Luciano N. Santos ◽

Raquel A.F. Neves ◽

Amanda C. Koureiche ◽

José Lailson-Brito

Keyword(s):

Risk Assessment ◽

Fish Species ◽

Mercury Concentration ◽

Biological Factors ◽

Human Risk Assessment ◽

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Environmental health science research and human risk assessment

Molecular Carcinogenesis ◽

10.1002/mc.2940140103 ◽

1995 ◽

Vol 14 (1) ◽

pp. 2-9 ◽

Author(s):

Kenneth Olden ◽

Jean-Louis Klein

Keyword(s):

Risk Assessment ◽

Environmental Health ◽

Science Research ◽

Health Science ◽

Human Risk Assessment ◽

Health Science Research ◽

Environmental Health Science

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Phytoavailability, human risk assessment and transfer characteristics of cadmium and zinc contamination from urban gardens in Kano, Nigeria

Journal of the Science of Food and Agriculture ◽

10.1002/jsfa.4583 ◽

2011 ◽

Vol 91 (15) ◽

pp. 2722-2730 ◽

Author(s):

Nafiu Abdu ◽

John O Agbenin ◽

Andreas Buerkert

Keyword(s):

Risk Assessment ◽

Urban Gardens ◽

Human Risk Assessment ◽

Transfer Characteristics ◽

Zinc Contamination

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Human Risk Assessment of Inhaled Irritants: Role of Sensory Stimulations from Spatially separated Nociceptors

10.1016/j.tox.2021.152929 ◽

2021 ◽

pp. 152929

Author(s):

Juergen Pauluhn ◽

John E. Whalan

Keyword(s):

Risk Assessment ◽

Human Risk Assessment ◽

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Interpretation of skeletal variations for human risk assessment: delayed ossification and wavy ribs

Birth Defects Research Part B Developmental and Reproductive Toxicology ◽

10.1002/bdrb.20133 ◽

2007 ◽

Vol 80 (6) ◽

pp. 473-496 ◽

Author(s):

Edward W. Carney ◽

Carole A. Kimmel

Keyword(s):

Risk Assessment ◽

Human Risk Assessment ◽

Delayed Ossification

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Molecular tools for the harmonisation of ecological and human risk assessment

Toxicology Letters ◽

10.1016/j.toxlet.2011.05.1021 ◽

2011 ◽

Vol 205 ◽

pp. S9

Author(s):

D. Spurgeon

Keyword(s):

Risk Assessment ◽

Molecular Tools ◽

Human Risk Assessment ◽

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Toxicity testing: New approaches and applications in human risk assessment

10.1016/0300-483x(85)90101-5 ◽

1985 ◽

Vol 37 (3-4) ◽

pp. 331-332

Author(s):

K.J. Netter

Keyword(s):

Risk Assessment ◽

Toxicity Testing ◽

Human Risk Assessment ◽

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