An in vitro dermal absorption study ring trial with 14C-Caffeine according to OECD test guideline 428

2021 ◽  
Vol 350 ◽  
pp. S249-S250
Author(s):  
S. Totti ◽  
F. Kluxen ◽  
F. Toner ◽  
L. Page ◽  
W. Maas ◽  
...  
Keyword(s):  
Dermal Absorption ◽  
Absorption Study ◽  
Ring Trial ◽  
Test Guideline ◽  
Oecd Test Guideline

Me-too validation study for in vitro skin irritation test with a reconstructed human epidermis model, KeraSkin™ for OECD test guideline 439

2020 ◽  
Vol 117 ◽  
pp. 104725
Author(s):  
Juhee Han ◽  
Seolyeong Kim ◽  
Su-Hyun Lee ◽  
Jin-Sik Kim ◽  
Yu Jin Chang ◽  
...  
Keyword(s):  
Validation Study ◽  
Skin Irritation ◽  
Human Epidermis ◽  
Reconstructed Human Epidermis ◽  
Irritation Test ◽  
Skin Irritation Test ◽  
Test Guideline ◽  
Oecd Test Guideline

scholarly journals Comparative assessment of 24-hr primary skin irritation test and human patch test data with in vitro skin irritation tests according to OECD Test Guideline 439 (for quasi-drugs in Japan)

2018 ◽  
Vol 43 (12) ◽  
pp. 751-768 ◽  
Author(s):  
Mariko Sugiyama ◽  
Masaharu Akita ◽  
Nathalie Alépée ◽  
Miyuki Fujishiro ◽  
Shigenobu Hagino ◽  
...  
Keyword(s):  
Patch Test ◽  
Test Data ◽  
Skin Irritation ◽  
Comparative Assessment ◽  
Irritation Test ◽  
Skin Irritation Test ◽  
Test Guideline ◽  
Oecd Test Guideline

Application of Liquid Chromatography-Direct-Electron Ionization-MS in an in Vitro Dermal Absorption Study: Quantitative Determination oftrans-Cinnamaldehyde

2011 ◽  
Vol 83 (22) ◽  
pp. 8537-8542 ◽  
Author(s):  
Achille Cappiello ◽  
Giorgio Famiglini ◽  
Veronica Termopoli ◽  
Helga Trufelli ◽  
Raniero Zazzeroni ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Quantitative Determination ◽  
Electron Ionization ◽  
Dermal Absorption ◽  
Absorption Study

scholarly journals Assessment of the human epidermal model LabCyte EPI-MODEL for In vitro skin corrosion testing according to the OECD test guideline 431

2010 ◽  
Vol 35 (3) ◽  
pp. 411-417 ◽  
Author(s):  
Masakazu Katoh ◽  
Fumiyasu Hamajima ◽  
Takahiro Ogasawara ◽  
Ken-ichiro Hata
Keyword(s):  
Corrosion Testing ◽  
Test Guideline ◽  
Oecd Test Guideline

scholarly journals Skin and Eye Irritation Assessment of Oil Palm (Elaeis guineensis) Leaf Extract for Topical Application

2018 ◽  
Vol 37 (4) ◽  
pp. 335-343 ◽  
Author(s):  
Nor Zuliana Yusof ◽  
Siti Salwa Abd Gani ◽  
Zafarizal Aldrin Azizul Hasan ◽  
Zainab Idris
Keyword(s):  
Oil Palm ◽  
Safety Assessment ◽  
Leaf Extract ◽  
Elaeis Guineensis ◽  
Dermal Fibroblasts ◽  
Hazard Identification ◽  
Eye Irritation ◽  
Test Guideline ◽  
Oecd Test Guideline

Many types of phytochemicals have been found to be present in oil palm leaf and could potentially be used as functional ingredients for skincare product. However, as of today, there is no published report on hazard identification and safety assessment of oil palm ( Elaeis guineensis) leaf extract (OPLE), particularly on skin and eye irritation. In this study, potential hazard of OPLE on skin and eye irritation was evaluated as an initial step to the safety assessment of OPLE. In vitro cell viability study of OPLE on normal human dermal fibroblasts showed that OPLE was nontoxic to the cells with percentage viability more than 90% after 24 and 48 hours of incubation. Skin irritation potential of OPLE was evaluated using in vitro SkinEthic reconstructed human epidermis (RHE) model (Organization for Economic Cooperation and Development [OECD] Test Guideline 439, 2015), while eye irritation potential was evaluated using in vitro SkinEthic Human corneal epithelium (HCE) model (OECD test guideline 492, 2017). Hazard identification results showed that OPLE at 1%, 5%, and 10% (wt/wt) was classified as nonirritant to the skin and eye where mean tissue viabilities of SkinEthic RHE and SkinEthic HCE were more than 50% and 60%, respectively. Therefore, we recommend a further safety assessment, such as human patch testing, to confirm the nonirritant of OPLE.

In vitro dermal absorption of propylidene phthalide, a cosmetic ingredient

2017 ◽  
Vol 280 ◽  
pp. S269
Author(s):  
Kyu-Bong Kim ◽  
Ji-young Kim ◽  
Jung Dae Lee ◽  
Hyun Jun Jang
Keyword(s):  
Dermal Absorption

In Vitro Assessment of Dermal Absorption

2020 ◽  
pp. 267-295
Author(s):  
John Kao
Keyword(s):  
Dermal Absorption ◽  
In Vitro Assessment
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