Reduction of animal usage by serial bleeding of mice for pharmacokinetic studies: application of robotic sample preparation and fast liquid chromatography–mass spectrometry

2001 ◽  
Vol 754 (1) ◽  
pp. 245-251 ◽  
Author(s):  
Kevin P. Bateman ◽  
Geneviève Castonguay ◽  
Lijing Xu ◽  
Steve Rowland ◽  
Deborah A. Nicoll-Griffith ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Sample Preparation ◽  
Pharmacokinetic Studies ◽  
Liquid Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Fast Liquid Chromatography

A validated liquid chromatography mass spectrometry method for the quantification of tinoridine hydrochloride in rat plasma and its application to pharmacokinetic studies

2015 ◽  
Vol 7 (5) ◽  
pp. 1965-1970 ◽  
Author(s):  
Pradipbhai D. Kalariya ◽  
Prinesh N. Patel ◽  
Challa Veerabhadra Swamy ◽  
R. Srinivas ◽  
M. V. N. Kumar Talluri
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Rat Plasma ◽  
Pharmacokinetic Studies ◽  
Liquid Chromatography Mass Spectrometry ◽  
Spectrometry Method ◽  
Mass Spectrometry Method ◽  
Chromatography Mass Spectrometry ◽  
Fast Liquid Chromatography

A selective, sensitive and fast liquid chromatography coupled with mass spectrometry method (LC-MS) has been developed and validated for the quantification of tinoridine hydrochloride in rat plasma.

Sign in / Sign up

Export Citation Format

Share Document