The diagnostic accuracy of core biopsy in palpable and non-palpable breast lesions

1997 ◽  
Vol 24 (2) ◽  
pp. 120-123 ◽  
Author(s):  
Ruud M. Pijnappel ◽  
Albert van Dalen ◽  
Inne H.M. Borel Rinkes ◽  
Jan G. van den Tweel ◽  
Willem P.Th.M. Mali
Keyword(s):  
Diagnostic Accuracy ◽  
Core Biopsy ◽  
Breast Lesions ◽  
Palpable Breast

Mammographic Fine Needle Biopsy of Non-Palpable Breast Lesions

1984 ◽  
Vol 25 (4) ◽  
pp. 273-276 ◽  
Author(s):  
M. Kehler ◽  
U. Albrechtsson
Keyword(s):  
Diagnostic Accuracy ◽  
Needle Biopsy ◽  
Fine Needle Biopsy ◽  
Breast Lesions ◽  
Malignant Cells ◽  
Fine Needle ◽  
The Past ◽  
Palpable Breast ◽  
Short Time ◽  
Observation Period

Results with a previously described device for fine needle biopsies of non-palpable breast lesions are reported. During the past 5 years 182 biopsies were performed and 133 of these yielded diagnostic cell material. In the series, 41 carcinomas were found and fine needle biopsy in all demonstrated malignant or probably malignant cells. In the biopsies evaluated as benign or probably benign, malignancy has not been found during the observation period of 4 to 59 months (mean 21.5 months). The device described is cheap and biopsy is easily performed and, if necessary, repeated in a short time. The diagnostic accuracy is high and carcinomas as small as 3 mm in diameter have been diagnosed.

scholarly journals Stereotactic Vacuum-Assisted Core Biopsy Results for Non-Palpable Breast Lesions

2014 ◽  
Vol 15 (13) ◽  
pp. 5171-5174 ◽  
Author(s):  
Filiz Agacayak ◽  
Alper Ozturk ◽  
Atilla Bozdogan ◽  
Derya Selamoglu ◽  
Gul Alco ◽  
...  
Keyword(s):  
Core Biopsy ◽  
Breast Lesions ◽  
Palpable Breast

scholarly journals Percutaneous core biopsy of palpable breast lesions: accuracy of frozen section histopathological exam in the diagnosis of breast cancer

2014 ◽  
Vol 41 (1) ◽  
pp. 07-10
Author(s):  
Roberto Luiz Carvalhosa Dos Santos ◽  
Ricardo Bassil Lasmar ◽  
Tereza Maria Pereira Fontes ◽  
Rachel De Carvalho Silveira De Paula Fonseca ◽  
Paula De Azevedo Brant Saldanha ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Predictive Value ◽  
Core Biopsy ◽  
Frozen Section ◽  
False Negative ◽  
Breast Lesions ◽  
Needle Core Biopsy ◽  
Excellent Correlation ◽  
Percutaneous Core Needle Biopsy ◽  
Palpable Breast

OBJECTIVE: to evaluate the accuracy of frozen section histopathology from fragments of tissue obtained by percutaneous core needle biopsy of palpable tumors in the diagnosis of breast cancer. METHODS: a cohort study was performed on 57 patients with palpable tumors and suspected breast cancer undergoing percutaneous thick needle core biopsy. The fragments were analyzed by the same pathologist. RESULTS: frozen section diagnosed 16 benign cases (28.6%) and 40 malignant (71.4%), whereas paraffin showed that 15 were benign (26.8%) and 41 malignant (73.2%). Histopathological examinations were concordant in 55 cases and there was one false-negative (6.2%). Statistics rates were: negative predictive value of 93.8%, positive predictive value of 100%, no false-positive (0%), one false negative (6.2%), specificity of 100%, sensitivity of 97 6%; observed agreement = 98.2%; expected agreement = 59.9%, Kappa = 0.955 [ 95% CI = 0.925-0.974, p < 0.01 ]. CONCLUSIONS: frozen section histopathological findings showed excellent correlation with the findings by the technique in paraffin in the fragments of palpable breast tumors obtained by thick needle percutaneous core biopsy (98.2% accuracy). Therefore, in these patients, it was possible to anticipate the diagnosis, staging and the breast cancer treatment planning.

Reproducibility of histological diagnoses and diagnostic accuracy of non palpable breast lesions

1994 ◽  
Vol 190 (1) ◽  
pp. 69-76 ◽  
Author(s):  
S. Bianchi ◽  
D. Palli ◽  
M. Galli ◽  
B. Arisio ◽  
A. Cappal ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Breast Lesions ◽  
Palpable Breast

Diagnostic Accuracy of Ultrasound in Palpable Breast Lesions

2020 ◽  
Vol 5 (3) ◽  
pp. 1196-1200
Author(s):  
Manish Raj Pathak ◽  
Mahesh Gautam ◽  
Rashmita Bhandari
Keyword(s):  
Positive Predictive Value ◽  
Diagnostic Accuracy ◽  
Negative Predictive Value ◽  
Diagnostic Tool ◽  
Predictive Value ◽  
Breast Lesions ◽  
Non Invasive ◽  
Malignant Lesions ◽  
Palpable Breast ◽  
Sensitivity Specificity

Introduction: Breast carcinoma is the second leading cause of cancer related mortality in females around the world. Ultrasound plays a key role in differentiating cystic and solid lesions and is a convenient and non-invasive diagnostic tool to differentiate between benign and malignant lesions. Objectives: The aim of this study is to evaluate the diagnostic accuracy of ultrasound in palpable breast lesions. Methodology: A prospective cross-sectional study was carried out in patients with palpable breast lesions who presented in Department of radio diagnosis and imaging of Nobel Medical collegefor a period of one-year from February 2019- January 2020 using ultrasound. A total of 60 patientswereevaluated in the study. Sensitivity, specificity, positive predictive value, negative predictive value and accuracy were calculated. Results: Out of 60 patients evaluated, ultrasound showed 46 (76.7%) cases to be benign and 14 (23.3%) cases to be malignant. FNAC revealed benign disease in 47 (78.3%) patients and malignant disease in 13 (21.7%) patients. The most common benign lesion was fibroadenoma. We found nearly 91.7% of the malignant lesions had spiculated margins and microcalcification. The sensitivity of ultrasound was 95.74% and specificity 92.3% with diagnostic accuracy 95%. Conclusion: Ultrasound is a convenient and non-invasive diagnostic tool with good sensitivity, specificity, positive predictive value, negative predictive value and accuracy in palpable breast lesions.

Vacuum-Assisted Core Biopsy (Mammotome) for the Diagnosis of Non-Palpable Breast Lesions: Four-Year Experience in an Italian Center

2005 ◽  
Vol 91 (4) ◽  
pp. 351-354 ◽  
Author(s):  
Raffaele Costantini ◽  
Augusto Sardellone ◽  
Cristiana Marino ◽  
Maria Adele Giamberardino ◽  
Paolo Innocenti ◽  
...  
Keyword(s):  
Core Biopsy ◽  
Breast Lesions ◽  
Negative Effects ◽  
Radiographic Appearance ◽  
Atypical Lobular Hyperplasia ◽  
Number Of Patients ◽  
Ductal Hyperplasia ◽  
Mammotome Biopsy ◽  
The Difference ◽  
Palpable Breast

Aims and background Microinvasive biopsy techniques are increasingly employed in the diagnostic assessment of non-palpable breast lesions (NPBLs). This study reports the four-year experience of an Italian surgical center in the evaluation of the diagnostic effectiveness versus adverse effects of vacuum-assisted core biopsy (Mammotome). Methods 314 NPBLs with a dubious ultrasound and/or radiographic appearance were subjected to mammography-guided (86) or ultrasound-guided (228) Mammotome biopsy. Results The procedure could be completed and was diagnostic in 305 cases (P <0.0001). Adverse events were transient lightheadedness. in two cases and moderate bleeding in three cases. Histological processing of the biopsies showed 227 cases of benign disease (74.42%), 68 cases of carcinoma (20 carcinomas in situ and 48 infiltrating carcinomas) (22.29%), nine cases of atypical ductal hyperplasia (2.95%) and one atypical lobular hyperplasia (0.33%). Only 12 patients reported mild discomfort relative to the procedure. The difference between the number of patients reporting discomfort and that of patients reporting no discomfort at all was highly significant (P <0.0001). Conclusions The results confirm that Mammotome biopsy is a highly effective procedure for the diagnosis of NPBLs, with minimal negative effects.

Use of the “Triple Test” for palpable breast lesions yields high diagnostic accuracy and cost savings

1995 ◽  
Vol 169 (5) ◽  
pp. 519-522 ◽  
Author(s):  
John Vetto ◽  
Rodney Pommier ◽  
Waldemar Schmidt ◽  
Mitchell Wachtel ◽  
Polly DuBois ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Cost Savings ◽  
Breast Lesions ◽  
High Diagnostic Accuracy ◽  
Triple Test ◽  
Palpable Breast

Ultrasound-guided core needle biopsy of non-palpable breast lesions: a prospective analysis in 204 cases

2005 ◽  
Vol 46 (7) ◽  
pp. 690-695 ◽  
Author(s):  
A. Vega BolÍvar ◽  
P. Alonso-Bartolomé ◽  
E. Ortega GarcÍa ◽  
F. Garijo Ayensa
Keyword(s):  
Core Needle Biopsy ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Core Biopsy ◽  
Breast Biopsy ◽  
Diagnostic Yield ◽  
Breast Lesions ◽  
Core Needle ◽  
Palpable Breast

Purpose: To assess the diagnostic value of ultrasound (US)-guided 14 G core needle breast biopsy in non-palpable suspicious breast lesions. Material and Methods: From August 1997 to April 2001, 198 patients with 204 suspicious non-palpable breast lesions underwent US-guided large core needle biopsy. Biopsies were performed with a free-hand technique using US equipment with a 7.5 MHz linear-array transducer; a minimum of three cores were obtained from each lesion. Pathological findings in US-guided core biopsy were correlated to findings in subsequent surgery or long-term (more than 2 years) imaging follow-up. Results: Among the 204 non-palpable breast lesions for which histopathological findings were obtained by US-guided core biopsy, 118 were malignant (114 carcinoma, 2 metastasis, 1 lymphoma, and 1 malignant phyllodes tumor) and 86 were benign (4 carcinoma and 82 benign lesions confirmed at surgery or after at least 2 years of follow-up). Sensitivity, specificity, positive predictive value, and negative predictive value for diagnosis of malignancy in our series were 97%, 100%, 100%, and 95%, respectively. Diagnostic yield with 1, 2, 3, and 4 specimens per lesion was 73.5%, 88%, 94%, and 97.5%, respectively. Conclusion: US-guided core needle biopsy is a sensitive percutaneous biopsy method for diagnosing non-palpable breast lesions. To achieve a high diagnostic yield, a minimum number of three cores per lesion is advisable.

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