scholarly journals MICROVASCULAR VASOMOTOR DYSREGULATION IS ASSOCIATED WITH MYOCARDIAL ISCHEMIA IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE

2014 ◽  
Vol 63 (12) ◽  
pp. A1628
Author(s):  
Ronnie Ramadan ◽  
Shabnam Seydafkan ◽  
Malik Obideen ◽  
Fabio Esteves ◽  
Doug Bremner ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Stable Coronary Artery Disease ◽  
Artery Disease

scholarly journals NON-INVASIVE FFR DERIVED FROM STANDARD ACQUIRED CORONARY COMPUTED TOMOGRAPHY ANGIOGRAPHY (CTA) DATASETS (FFRCT) FOR THE DIAGNOSIS OF MYOCARDIAL ISCHEMIA IN PATIENTS WITH CORONARY ARTERY DISEASE (CAD): FIRST DATA OF CLINICAL USE. COMPARISON WITH INVASIVE MEASUREMENT

2018 ◽  
pp. 47-55 ◽  
Author(s):  
E. S. Pershina ◽  
V. E. Sinitsin ◽  
E. A. Mershina ◽  
I. M. Arkhipova ◽  
S. P. Semitko ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Computed Tomography Angiography ◽  
Coronary Computed Tomography Angiography ◽  
Stable Coronary Artery Disease ◽  
Coronary Computed Tomography ◽  
Non Invasive ◽  
Artery Disease

Objectives: to determine the diagnostic performance of non-invasive FFR derived from standard acquired coronary computed tomography angiography (CTA) datasets (FFRCT) for the diagnosis of myocardial ischemia in patients with suspected stable coronary artery disease (CAD).Methods.Prospective study included 16 patients ((m/f – 13/3 mean age 47.8 ± 2.3 years) with CAD and coronary stenosis 40–75% lumen reduction. Coronary CTA was performed prior to ICA with invasive FFR measurement. FFRCT was calculated and interpreted in a blinded fashion by an independent Core Laboratory (HeartFlow, USA). Results were compared to invasively measured FFR, with ischemia defined as FFRCT or FFR ≤ 0.80.Results. The area under the receiver operating characteristic curve (95% CI) for FFCT was 0.90. Per-vessel sensitivity and specificity to identify myocardial ischemia were 91% and 89% for FFRCT.Conclusion.FFRCT provides high diagnostic accuracy, and discrimination for the diagnosis of hemodynamically significant CAD with invasive FFR as the reference standard. 

Circadian Variation of Myocardial Ischemia in Patients with Stable Coronary Artery Disease

1991 ◽  
Vol 8 (5) ◽  
pp. 385-398 ◽  
Author(s):  
Dirk Hausmann ◽  
Paul R. Lichtlen ◽  
Peter Nikutta ◽  
Paul Wenzlaff ◽  
Werner G. Daniel
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Stable Coronary Artery Disease ◽  
Circadian Variation ◽  
Artery Disease
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