scholarly journals ELEVATED BLOOD PRESSURE DURING EXERCISE IS ASSOCIATED WITH CEREBRAL WHITE MATTER LESIONS ESPECIALLY IN NORMOTENSIVE SUBJECTS

2015 ◽  
Vol 65 (10) ◽  
pp. A1402
Author(s):  
Woo-In Yang ◽  
Sang-Wook Lim ◽  
Yeongmin Lim ◽  
Jae-Youn Moon ◽  
Jung Hoon Sung ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
White Matter Lesions ◽  
Elevated Blood Pressure ◽  
Cerebral White Matter ◽  
Elevated Blood ◽  
Cerebral White Matter Lesions ◽  
Normotensive Subjects

Association of elevated blood pressure during exercise with cerebral white matter lesions

2018 ◽  
Vol 27 (3) ◽  
pp. 166-172
Author(s):  
Woo-In Yang ◽  
In-Jai Kim ◽  
Mi-Sun Kim ◽  
Sang-Hoon Kim ◽  
Jae-Youn Moon ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
White Matter Lesions ◽  
Elevated Blood Pressure ◽  
Cerebral White Matter ◽  
Elevated Blood ◽  
Cerebral White Matter Lesions

Prevention of White-Matter Lesions Through Control of Cerebrovascular Risk Factors

2003 ◽  
Vol 15 (S1) ◽  
pp. 147-151 ◽  
Author(s):  
Charles DeCarli
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
Systolic Blood Pressure ◽  
Strong Association ◽  
Treatment Strategies ◽  
White Matter Lesions ◽  
Elevated Blood Pressure ◽  
Cerebral White Matter ◽  
Elevated Blood ◽  
Atherosclerotic Vascular Disease

Multiple epidemiological and brain imaging studies show a strong association between elevations in systolic blood pressure and lesions of cerebral white matter. The association between white-matter lesions and systolic blood pressure persists even if individuals are receiving treatment, suggesting that these individuals may be undertreated. In addition, these studies suggest that lesions of cerebral white matter may serve as markers for atherosclerotic vascular disease. Treatment strategies, therefore, should focus on early and aggressive management of elevated blood pressure, but definitions of elevated blood pressure may need to be revised downward to achieve best results.

scholarly journals White Matter Lesions and Cognitive Impairment as Silent Cerebral Disease in Hypertension

2006 ◽  
Vol 6 ◽  
pp. 494-501 ◽  
Author(s):  
Cristina Sierra ◽  
Antonio Coca
Keyword(s):  
Blood Pressure ◽  
Cognitive Impairment ◽  
White Matter ◽  
Indirect Evidence ◽  
White Matter Lesions ◽  
Cerebral White Matter ◽  
Cognitive Changes ◽  
Cerebral Disease ◽  
Functional Changes ◽  
Cerebral White Matter Lesions

Although the pathogenesis and clinical significance of cerebral white matter lesions remain controversial, it is well established that age and hypertension are the most important factors related to the presence of these lesions. Hypertension is known to be the most important factor for developing stroke and vascular dementia. In addition, the presence of cerebral white matter lesions is an important prognostic factor for the development of stroke, and also for cognitive impairment and dementia. The mechanisms underlying hypertension-related cognitive changes are complex and are not yet fully understood. Correlations between cerebral white matter lesions and elevated blood pressure provide indirect evidence that structural and functional changes in the brain over time may lead to lowered cognitive functioning when blood pressure control is poor or lacking.Some authors have suggested that the presence of white matter lesions in hypertensive patients could be considered an early marker of brain damage.

A follow-up study of blood pressure and cerebral white matter lesions

1999 ◽  
Vol 46 (6) ◽  
pp. 827-833 ◽  
Author(s):  
Frank-Erik De Leeuw ◽  
Jan Cees De Groot ◽  
Matthijs Oudkerk ◽  
Jacqueline C. M. Witteman ◽  
Albert Hofman ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
White Matter Lesions ◽  
Cerebral White Matter ◽  
Follow Up Study ◽  
Cerebral White Matter Lesions

scholarly journals Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions

JAMA ◽  
2019 ◽  
Vol 322 (6) ◽  
pp. 524 ◽  
Author(s):  
◽  
Ilya M. Nasrallah ◽  
Nicholas M. Pajewski ◽  
Alexander P. Auchus ◽  
Gordon Chelune ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
Blood Pressure Control ◽  
White Matter Lesions ◽  
Pressure Control ◽  
Cerebral White Matter ◽  
Cerebral White Matter Lesions

scholarly journals Associations between Ambulatory Blood Pressure Parameters and Cerebral White Matter Lesions

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Cristina Sierra
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
Ambulatory Blood Pressure ◽  
Blood Pressure Monitoring ◽  
White Matter Lesions ◽  
The Elderly ◽  
Organ Damage ◽  
Common Finding ◽  
Cerebral White Matter ◽  
Cerebral White Matter Lesions

Silent cerebral white matter lesions (WMLs) are a common finding on magnetic resonance imaging of the brain in the elderly. However, in patients with hypertension, WMLs tend to occur earlier in life and appear to be more severe. There is a body of evidence that supports the idea that WMLs in asymptomatic hypertensive patients should be considered a silent early marker of brain damage. It is known that ambulatory blood pressure monitoring (ABPM) correlates more closely with hypertension-related organ damage than office blood pressure. This paper focuses on the associations between blood pressure parameters obtained by 24-hour ABMP and cerebral WMLs.

scholarly journals The Association Between Blood Pressure, Hypertension, and Cerebral White Matter Lesions

Hypertension ◽  
2004 ◽  
Vol 44 (5) ◽  
pp. 625-630 ◽  
Author(s):  
Ewoud J. van Dijk ◽  
Monique M.B. Breteler ◽  
Reinhold Schmidt ◽  
Klaus Berger ◽  
Lars-Göran Nilsson ◽  
...  
Keyword(s):  
Blood Pressure ◽  
White Matter ◽  
White Matter Lesions ◽  
Cerebral White Matter ◽  
Cerebral White Matter Lesions
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