Developmental Changes in Biogenic Amine Levels in the Central Nervous System and the Haemolymph of the Eastern Death's Head Hawk Moth, Acherontia styx (Lepidoptera: Sphingidae)

1997 ◽  
Vol 116 (3) ◽  
pp. 219-225
Author(s):  
Edward William Awad ◽  
Muhammed Hadi Amiri ◽  
Rajan Sheen Stephen
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Biogenic Amine ◽  
Developmental Changes ◽  
Hawk Moth ◽  
The Central Nervous System

scholarly journals Developmental changes in purine phosphoribosyltransferases in human and rat tissues

1976 ◽  
Vol 160 (3) ◽  
pp. 565-576 ◽  
Author(s):  
A Adams ◽  
R A Harkness
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Developmental Changes ◽  
Assay Method ◽  
Rat Tissues ◽  
Adenine Phosphoribosyltransferase ◽  
Wide Range ◽  
The Central Nervous System ◽  
Guanine And Adenine ◽  
Hypoxanthine Guanine Phosphoribosyltransferase

1. The hypoxanthine/guanine and adenine phosphoribosyltransferase activities in a wide variety of human tissues were studied during their growth and development from foetal life onward. A wide range of activities develop after birth, with especially high values in the central nervous system and testes. 2. Postnatal development of hypoxanthine/guanine phosphoribosyltransferase was also defined in the rat. Although there were increases in the central nervous system and testes, there was also a rise in activity in the liver, which was less marked in man. 3. A sensitive radiochemical assay method, using dTTP to inhibit 5′-nucleotidase activity, suitable for tissue extracts, was developed. 4. No definite evidence of the existence of tissue-specific isoenzymes of hypoxanthine/guanine or adenine phosphoribosyltransferase was found. Hypoxanthine/guanine phosphoribosyltransferase in testes, however, had a significantly different thermal-denaturation rate constant. 5. The findings are discussed in an attempt to relate activity of hypoxanthine/guanine phosphoribosyltransferase to biological function. Growth as well as some developmental changes appear to be related to increase in the activity of this enzyme.

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