Dynorphin-A(1–17) decreases nitric oxide release and cytotoxicity induced with lipopolysaccharide plus interferon-γ in murine macrophage cell line J774

2003 ◽  
Vol 57 (8) ◽  
pp. 351-358 ◽  
Author(s):  
Jelka Gabrilovac ◽  
Tihomir Balog ◽  
Ana Andreis
FEBS Letters ◽  
2000 ◽  
Vol 478 (1-2) ◽  
pp. 95-99 ◽  
Author(s):  
Thomas Moeslinger ◽  
Roswitha Friedl ◽  
Ivo Volf ◽  
Monika Brunner ◽  
Elisabeth Koller ◽  
...  

2011 ◽  
Vol 29 (8) ◽  
pp. 679-685 ◽  
Author(s):  
A. Koc ◽  
T. Ozkan ◽  
A. Z. Karabay ◽  
A. Sunguroglu ◽  
F. Aktan

2006 ◽  
Vol 51 (4) ◽  
pp. 339-344 ◽  
Author(s):  
V.K. Gopinath ◽  
M. Musa ◽  
A.R. Samsudin ◽  
P. Lalitha ◽  
W. Sosroseno

2000 ◽  
Vol 28 (02) ◽  
pp. 217-226 ◽  
Author(s):  
Hiroshi Kawamata ◽  
Hiroshi Ochiai ◽  
Naoki Mantani ◽  
Katsutoshi Terasawa

We have investigated the effect of Juzen-taiho-to (TJ-48) on inducible NO synthase (iNOS) expression and nitric oxide (NO) production in RAW264.7 cells, a murine macrophage cell line. TJ-48-lipopolysaccharide (LPS) combination induced iNOS mRNA expression earlier, stronger and remained longer that paralleled but with a higher NO production compared to LPS stimulation. TJ-48 itself showed no inducible effect either no NO production or iNOS mRNA expression. This phenomenon could be considered to contribute, at least in part, to the beneficial effects of TJ-48 through the iNOS-mediated activation of biodefense mechanism.


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