Spatial and verbal working memory deficits in schizophrenia

1997 ◽  
Vol 24 (1-2) ◽  
pp. 138
Author(s):  
Stephan F. Taylor ◽  
Edward E. Smith ◽  
John Jonides ◽  
Laura Decker ◽  
Irma C. Smet ◽  
...  
2000 ◽  
Vol 6 (5) ◽  
pp. 548-555 ◽  
Author(s):  
ROXANNA FARINPOUR ◽  
EILEEN M. MARTIN ◽  
MICHAEL SEIDENBERG ◽  
DAVID L. PITRAK ◽  
KENNETH J. PURSELL ◽  
...  

Recent evidence suggests that HIV-seropositive drug users are impaired on tasks of visuospatial working memory compared with drug users seronegative for HIV. In the current study we evaluated the performance of 30 HIV-seropositive male drug users and 30 risk-matched seronegative controls on two measures of verbal working memory, the Listening Span and the verbal Self Ordered Pointing Task. Impaired working memory performance was significantly more common among HIV-seropositive persons compared to controls, with the highest incidence of deficit among symptomatic participants. These findings indicate that working memory deficits in persons with HIV are not domain-specific and can be demonstrated reliably in drug users. (JINS, 2000, 6, 548–555.)


2016 ◽  
Vol 47 (1) ◽  
pp. 123-130 ◽  
Author(s):  
Aleksandra Gruszka ◽  
Daniel Bor ◽  
Roger R. Barker ◽  
Edward Necka ◽  
Adrian M. Owen

Abstract Idiopathic Parkinson’s disease (PD) impairs working memory, but the exact nature of this deficit in terms of the underlying cognitive mechanisms is not well understood. In this study patients with mild clinical symptoms of PD were compared with matched healthy control subjects on a computerized battery of tests designed to assess spatial working memory and verbal working memory. In the spatial working memory task, subjects were required to recall a sequence of four locations. The verbal working memory task was methodologically identical except for the modality of the stimuli used, requiring subjects to orally recall a sequence of six digits. In either case, half of the sequences were structured in a way that allowed ‘chunking’, while others were unstructured. This manipulation was designed to dissociate the strategic component of task performance from the memory-load component. Mild medicated patients with PD were impaired only on the structured versions of the verbal working memory tasks. The analogous deficit in the spatial working memory was less pronounced. These findings are in agreement with the hypothesis that working memory deficits in PD reflect mainly the executive component of the tasks and that the deficits may be at least partly modality-independent.


2009 ◽  
Vol 166 (1) ◽  
pp. 46-53 ◽  
Author(s):  
Sezen Gokcen ◽  
Emre Bora ◽  
Serpil Erermis ◽  
Hande Kesikci ◽  
Cahide Aydin

2014 ◽  
Vol 153 (1-3) ◽  
pp. 38-41 ◽  
Author(s):  
Jens Gisselgård ◽  
Liss Gøril Anda ◽  
Kolbjørn Brønnick ◽  
Johannes Langeveld ◽  
Wenche ten Velden Hegelstad ◽  
...  

2004 ◽  
Vol 19 (4) ◽  
pp. 225-234 ◽  
Author(s):  
Michelle Wareing ◽  
John E. Fisk ◽  
Philip Murphy ◽  
Catharine Montgomery

2007 ◽  
Vol 46 (4) ◽  
pp. 196-202 ◽  
Author(s):  
Doris-Eva Bamiou ◽  
Nicole G. Campbell ◽  
Frank E. Musiek ◽  
Rachael Taylor ◽  
W.K. Chong ◽  
...  

Author(s):  
Jörg-Tobias Kuhn ◽  
Elena Ise ◽  
Julia Raddatz ◽  
Christin Schwenk ◽  
Christian Dobel

Abstract. Objective: Deficits in basic numerical skills, calculation, and working memory have been found in children with developmental dyscalculia (DD) as well as children with attention-deficit/hyperactivity disorder (ADHD). This paper investigates cognitive profiles of children with DD and/or ADHD symptoms (AS) in a double dissociation design to obtain a better understanding of the comorbidity of DD and ADHD. Method: Children with DD-only (N = 33), AS-only (N = 16), comorbid DD+AS (N = 20), and typically developing controls (TD, N = 40) were assessed on measures of basic numerical processing, calculation, working memory, processing speed, and neurocognitive measures of attention. Results: Children with DD (DD, DD+AS) showed deficits in all basic numerical skills, calculation, working memory, and sustained attention. Children with AS (AS, DD+AS) displayed more selective difficulties in dot enumeration, subtraction, verbal working memory, and processing speed. Also, they generally performed more poorly in neurocognitive measures of attention, especially alertness. Children with DD+AS mostly showed an additive combination of the deficits associated with DD-only and A_Sonly, except for subtraction tasks, in which they were less impaired than expected. Conclusions: DD and AS appear to be related to largely distinct patterns of cognitive deficits, which are present in combination in children with DD+AS.



2012 ◽  
Author(s):  
Klaus Oberauer ◽  
Stephan Lewandowsky

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