Xylazine (Chanazine®) as an epidural anaesthetic agent in sheep

1998 ◽  
Vol 27 (1) ◽  
pp. 85-87 ◽  
Author(s):  
A. Mohammed ◽  
M.S. Liman
1985 ◽  
Vol 53 (01) ◽  
pp. 095-098 ◽  
Author(s):  
C R Jones ◽  
R McCabe ◽  
C A Hamilton ◽  
J L Reid

SummaryPaired blood samples were obtained from mothers (venous) and babies (cord venous blood) at the time of delivery by caesarean section under epidural anaesthetic. Fetal platelets failed to aggregate in response to adrenaline in vitro although adrenaline could potentiate the threshold response to adenosine diphosphate (1 μM). Fetal platelet responses to collagen and 8 Arg vasopressin did not differ significantly from maternal responses. Maternal and fetal platelets also showed similar inhibition of aggregation after activation of adenylate cyclase (PGE1 and parathormone), in contrast to the inhibition of adenylate cyclase by adrenaline.Alpha2 adrenoceptors were investigated using [3H] yohimbine binding receptor number and were reduced modestly but significantly on fetal compared to maternal platelets. The failure of fetal platelet aggregation in response to adrenaline appears to be related to a failure of receptor coupling and may represent a delayed maturation of fetal platelet alpha receptors or a response- to increased circulating catecholamines during birth.


BMJ ◽  
1956 ◽  
Vol 2 (4999) ◽  
pp. 969-972 ◽  
Author(s):  
R. Bryce-Smith ◽  
H. D. O'Brien

2016 ◽  
Vol 117 (2) ◽  
pp. 267 ◽  
Author(s):  
C. Kakazu ◽  
M. Lippmann ◽  
D. Hsu
Keyword(s):  

2009 ◽  
Vol 95 (3) ◽  
pp. 145-150 ◽  
Author(s):  
S J Mercer

AbstractAnaesthesia for surgery during armed conflict was traditionally based on simple and reliable techniques. These often required a minimum of equipment and drugs while ensuring rapid and safe patient recovery. Ketamine, which first became available in Britain in the 1970s, was thought to offer certain favorable characteristics for use as a military anaesthetic agent. This article discusses the use of ketamine in many of the major armed conflicts that have occurred since its introduction. It also catalogues the methods used by anaesthetists at the time and their opinions of the drug’s success.


2014 ◽  
Vol 23 (1) ◽  
pp. 8-13
Author(s):  
Idris Ali ◽  
Amirul Islam ◽  
Golam Morshed ◽  
Nurul Islam ◽  
Ashia Ali ◽  
...  

Background: Adjuvant used with local anaesthetic agent in caudal is more effective for post operative analgesia in children . Aim and objective: To find out the duration and quality of caudal analgesia in children undergoing genitourinary surgery by combination of bupivacaine and midazolam. Methods: A total number of sixty patients ASA grade I&II were selected randomly as per inclusion & exclusion criteria in two groups. Thirty in each group. In group A, caudal block was given by bupivacainemidazolam mixture and in group B, caudal block was given by bupivacaine in lateral decubitus position, just after completion of surgery before reversed from GA. In post operative period arterial blood pressure, heart rate, and duration of analgesia were recorded. Results: There was no significant difference between the groups of blood pressure, heart rate, and pain score up to 30 min but after one hour of post operative period pain scores were significant(p<0.05). Conclusion: Midazolam improves the duration and quality of analgesic effect of bupivacaine. DOI: http://dx.doi.org/10.3329/jbsa.v23i1.18152 Journal of BSA, 2010; 23(1): 8-13


1969 ◽  
Vol 3 (2) ◽  
pp. 101-106 ◽  
Author(s):  
R. Cook ◽  
R. G. Dorman

A simple and effective method for anaesthetising germ-free rabbits and rats for the collection of heart-blood samples is described. The anaesthetic agent, a mixture of 2 or 4 per cent halothane in oxygen, was passed into the germ-free isolators through a tube sealed into the wall and fitted at each end with a high-efficiency gas line filter.


1991 ◽  
Vol 35 (4) ◽  
pp. 370-370
Author(s):  
William Campbell Edmondson ◽  
John E. Peacock

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