scholarly journals Transcranial Magnetic Stimulation for Borderline Personality Disorder: Rationale, Stimulation Site and Methods

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
L. Cailhol ◽  
E. Bui ◽  
B. Roussignol ◽  
A.-H. Moncany ◽  
R. Klein ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Transcranial Magnetic Stimulation ◽  
Personality Disorder ◽  
Interpersonal Relationships ◽  
Magnetic Stimulation ◽  
Suicide Attempts ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Controlled Trial ◽  
Borderline Personality ◽  
Post Traumatic Stress

Borderline personality disorder (BPD) is characterized by pervasive instability in moods, interpersonal relationships, self-image, and behavior. This disorder is associated with a significant rate of suicide attempts and completed suicides (4 to 10%), a major impairment in social functioning and an increased healthcare utilization cost. Treatments available include psychotherapy and pharmacotherapy. Research has shown some efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) on post-traumatic stress disorder and mood disorder which both share common biological or clinical features with BPD. It is then likely that rTMS might prove efficient on BPD symptoms.A review of the literature on neuroimaging and neuropsychology of BPD shows a hypoactivity of the dorsolateral prefrontal cortex which may be a potential target site for rTMS.We will conduct a pilot randomized sham-controlled trial on 30 BPD patients assessing the efficacy of a 10-day course of daily rTMS on neuropsychological tasks, BPD symptoms severity, risk taking behaviour, depression and general psychopathology.

Low Compliance to Pharmacological Treatment of Severe Chronic Illness: Passive Suicide Ideation in Borderline Personality Disorder?

2017 ◽  
Vol 41 (S1) ◽  
pp. S711-S711
Author(s):  
M. Bonea ◽  
I. Miclutia
Keyword(s):  
Liver Cirrhosis ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Interpersonal Relationships ◽  
Suicide Ideation ◽  
Suicide Attempts ◽  
Treatment Plan ◽  
Primary Hypothyroidism ◽  
Borderline Personality ◽  
Affective Instability

IntroductionThe core features of Borderline Personality Disorder (BPD), such as deliberate self-harm, suicide attempts and demandingness in interpersonal relationships persist with age, even though impulsivity decreases. Impairing progressive disease combined with affective instability and chronic feelings of emptiness can lead to a desire for death.ObjectivesTo present a case of BPD with severe chronic endocrine pathology and liver cirrhosis who refused to take his treatment as prescribed.MethodsA case report is presented and discussed.ResultsWe report the case of a 61-year-old man with BPD and liver cirrhosis, complex endocrine pathology (pituitary adenoma, diabetes insipidus and primary hypothyroidism), type 2 diabetes mellitus with insulin therapy, essential hypertension and alcohol use disorder. He had a history of 5 suicide attempts caused by marked feelings of rejection and emptiness and a pattern of unstable relationships and lack of commitment, thus his marriage lasted only 2 years. He idealized and was extremely familiar with his clinician and displayed marked affective instability (dysphoria, periods of anger and despair, affective ambivalence towards his parents and recurrent depressive symptoms). Because of his liver disease, the psychotropic medication was ceased by his physician. The patient refused to follow the rest of his treatment plan and diet as prescribed, resulting in the deterioration of his somatic status. The patient denied an active suicidal ideation, but did not explain his non-compliance.ConclusionThe impairment from BPD and the risk of suicide persist even in older age affecting the outcome of co-morbid somatic conditions.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Borderline Personality Disorder

2018 ◽  
pp. 245-270
Author(s):  
Carol S. North ◽  
Sean H. Yutzy
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Suicide Attempts ◽  
Controlled Trial ◽  
Borderline Personality ◽  
Historical Background ◽  
Self Mutilation ◽  
History Of ◽  
The Common ◽  
Cognitive Problems

Borderline personality disorder is a fairly recent label of a variously conceptualized phenomenon which has been characterized by affective instability and emotional crises, cognitive problems, impulsivity, and intense and unstable personal relationships. This chapter reviews the historical background, epidemiology, and clinical picture (including comorbidity) of borderline personality disorder. Although progress toward validation of this diagnosis has been made, the current definition does not appear to meet the accepted gold standard criteria for a syndrome that is currently considered valid (and reliable). The natural history of what is known is reviewed, as well as the common complications, including self-mutilation and suicide attempts. Treatment remains challenging at best, with few interventions meeting rigorous randomized controlled trial standards.

Neurophysiological Correlates of Borderline Personality Disorder: A Transcranial Magnetic Stimulation Study

2009 ◽  
Vol 65 (4) ◽  
pp. 313-318 ◽  
Author(s):  
Sven Barnow ◽  
Kathleen A. Völker ◽  
Bertram Möller ◽  
Harald J. Freyberger ◽  
Carsten Spitzer ◽  
...  
Keyword(s):  
Borderline Personality Disorder ◽  
Transcranial Magnetic Stimulation ◽  
Personality Disorder ◽  
Magnetic Stimulation ◽  
Borderline Personality
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