The FCFA Currency: An Eminently Linguistic Issue

In a situation of illiteracy at a rate of 54%, with over 80% of the population not speaking French (ANSD, 2013), it is very difficult to carry out effective development policies in Senegal without taking into account the language issue. From this point of view, the FCFA currency, which is expressed in French, poses a lot of problems for the African populations of the franc zone. The debate around this currency has so far been more focused on financial or fiduciary aspects than on the fundamental mechanisms that help to better understand the environment in which economic agents operate. Beyond its linguistic symbolism steeped in history, the FCFA creates cognitive problems that make it difficult for African populations to use it. We will try in this article to show, by an analytical approach, that the denomination of a currency involves the interaction of several fields of investigation. These are economic, historical, sociological, political, and above all, linguistic. From this angle, there is reason to be interested in the Academy of African Languages (ACALAN) in the resolution of this unit of measurement.

Nanoparticles for Diagnosis and Target Therapy in Pediatric Brain Cancers

Pediatric brain tumors represent the most common types of childhood cancer and novel diagnostic and therapeutic solutions are urgently needed. The gold standard treatment option for brain cancers in children, as in adults, is tumor resection followed by radio- and chemotherapy, but with discouraging therapeutic results. In particular, the last two treatments are often associated to significant neurotoxicity in the developing brain of a child, with resulting disabilities such as cognitive problems, neuroendocrine, and neurosensory dysfunctions/deficits. Nanoparticles have been increasingly and thoroughly investigated as they show great promises as diagnostic tools and vectors for gene/drug therapy for pediatric brain cancer due to their ability to cross the blood–brain barrier. In this review we will discuss the developments of nanoparticle-based strategies as novel precision nanomedicine tools for diagnosis and therapy in pediatric brain cancers, with a particular focus on targeting strategies to overcome the main physiological obstacles that are represented by blood–brain barrier.

Cognitive Impairment in People with Epilepsy

People with epilepsy frequently have cognitive impairment. The majority of cognitive problems is influenced by a variety of interlinked factors, including the early onset of epilepsy and the frequency, intensity and duration of seizures, along with the anti-epileptic drug treatment. With a systematic review, we investigate significant factors about the cognitive impairment in epilepsy. Most cognitive problems in adult people with epilepsy include memory, attention and executive function deficits. However, which cognitive area is mainly affected highly depends on the location of epileptic activity. Moreover, modifications in signalling pathways and neuronal networks have an essential role in both the pathophysiology of epilepsy and in the mechanism responsible for cognitive impairment. Additionally, studies have shown that the use of polytherapy in the treatment of epilepsy with anti-epileptic drugs (AEDs) heightens the risk for cognitive impairment. It can be challenging to distinguish the contribution of each factor, because they are often closely intertwined.

The Early Motor Repertoire in Preterm Infancy and Cognition in Young Adulthood: Preliminary Findings

Objective: Preterm birth poses a risk to cognition during childhood. The resulting cognitive problems may persist into young adulthood. The early motor repertoire in infancy is predictive of neurocognitive development in childhood. Our present aim was to investigate whether it also predicts neurocognitive status in young adulthood. Method: We conducted an explorative observational follow-up study in 37 young adults born at a gestational age of less than 35 weeks and/or with a birth weight below 1200 g. Between 1992 and 1997, these individuals were videotaped up until 3 months’ corrected age to assess the quality of their early motor repertoire according to Prechtl. The assessment includes general movements, fidgety movements (FMs), and a motor optimality score (MOS). In young adulthood, the following cognitive domains were assessed: memory, speed of information processing, language, attention, and executive function. Results: Participants in whom FMs were absent in infancy obtained lower scores on memory, speed of information processing, and attention than those with normal FMs. Participants with aberrant FMs, that is, absent or abnormal, obtained poorer scores on memory, speed of information processing speed, attention, and executive function compared to peers who had normal FMs. A higher MOS was associated with better executive function. Conclusions: The quality of the early motor repertoire is associated with performance in various cognitive domains in young adulthood. This knowledge may be applied to enable the timely recognition of preterm-born individuals at risk of cognitive dysfunctions.

Mental Disorders in Children and Adolescents With Autism

Children and adolescents with autism frequently have symptoms of various mental disorders along with the features that define autism. Problems with anxiety, depression, emotion regulation, cognitive problems, and associated behavioural problems occur in children with autism of all ages. Overall, high rates of several psychiatric disorders have been reported in individuals with autism. Several authors have suggested cognitive and behaviour therapy (CBT) as a very useful intervention therapy, which can apply in schools, in order to help these children with autism and mental health disorders. It is also important the use of information and communications technology (ICT) and other computer programs to support students with autism in education. Therefore, with a coordinated effort to use this intervention program, schools have an opportunity to address the goals of improving social, emotional, and behavioural competence for these students and minimising the impact of established emotional, behavioural, or educational disorders.

Ekolingwistyka w dobie antropocenu: w stronę integracji i konsiliencji

Celem artykułu jest ukazanie głównych wyzwań antropocenu dla językoznawstwa oraz wynikający z nich kierunek rozwoju ekolingwistyki w stronę konsiliencji, rozumianej jako idea systematycznego poszukiwania zależności przyczynowych między zjawiskami z różnych dziedzin wiedzy. Integracyjny model ekolingwistyki, który jest budowany od niespełna dekady, zostanie przedstawiony w powiązaniu z najtrudniejszymi problemami poznawczymi „epoki człowieka”, do których zalicza się przełamywanie antropocentryzmu oraz problematyzowanie pojęcia natury. Odpowiedzią ekolingwistów jest sformułowanie zasady nielokalności języka oraz jego znaturalizowany ogląd w hipotezie rozszerzonej ekologii. Z tymi nowymi ideami wiążą się nadzieje na to, że ekolingwistyka nie będzie traktowana jako tematyczny dział językoznawstwa, a stanie się awangardą w takim myśleniu o języku, które dotrzyma kroku trudnym wyzwaniom antropocenu. Ecolinguistics in the Anthropocene Era: Towards Integration and Consilience Summary: The aim of the paper is to present the main challenges that the Anthropocene presents to linguistics, and discuss the subsequent development of ecolinguistics towards consilience, understood as the idea of a systematic search for causal relationships between phenomena from various fields of science. The integrative model of ecolinguistics, which has been built for less than a decade, will be presented in relation to the most difficult cognitive problems of the Human Era, such as the overcoming of anthropocentrism and the addressing of the concept of nature. The solution proposed by ecolinguists is the principle of the non-locality of language and the nature-oriented view of language that follows the Extended Ecology Hypothesis. These new ideas will, hopefully, lead to considering ecolinguistics not so much as a thematic branch of linguistics, but as the avant-garde in such thinking about language that will keep pace with the challenges of the Anthropocene.

Heuristics as a cognitive function

The study conceptualizes science fiction as heuristics. To implement this conceptualization, a hybrid definition of science fiction is proposed: science fiction is a kind of fiction whose works can be characterized by secondary artistic conventionality, cognitive estrangement, and test of an intellectual idea or fantastic assumption. As an operational characterization of heuristics, V. Spiridonov’s concept of heuristics is used. Science fiction can be considered as a kind of heuristics under specific conditions, for example, when science fiction work contains the reflected-out heuristics or when heuristics are brought as science fiction work to stimulate the intuitive flash of the thought or insight. However, science fiction can only be regarded as heuristics with certain reservations: science fiction primarily solves artistic problems while heuristics primarily solve cognitive problems: and they can function independently of each other. But it shows that a heuristic function can be attributed to science fiction to solute a problem or to gain a piece of new knowledge (to make a discovery) in an intellectually and creative way.

Psychological symptoms, mental fatigue and behavioural adherence after 72 continuous days of strict lockdown during the COVID-19 pandemic in Argentina

BackgroundAn early and prolonged lockdown was adopted in Argentina during the first wave of COVID-19. Early reports evidenced elevated psychological symptoms.AimsTo explore if the prolonged lockdown was associated with elevated anxiety and depressive symptoms; if mental fatigue was associated with lockdown adherence (a phenomenon called ‘behavioural fatigue’); and if financial concerns were associated with lockdown adherence and emotional symptoms.MethodThe survey included standardised questionnaires to assess depressive (PHQ-9) and anxious (GAD-7) symptoms, mental fatigue, risk perception, lockdown adherence, financial concerns, daily stress, loneliness, intolerance to uncertainty, negative repetitive thinking and cognitive problems. LASSO regression analyses were carried out to predict depression, anxiety and lockdown adherenceResultsThe survey reached 3617 adults (85.2% female) from all provinces of Argentina after 72 days of lockdown. Data were collected between 21 May 2020 and 4 June 2020. In that period, Argentina had an Oxford stringency index of 85/100. Of those surveyed, 45.6% and 27% met the cut-offs for depression and anxiety, respectively. Mental fatigue, cognitive failures and financial concerns were correlated with psychological symptoms, but not with adherence to lockdown. In regression models, mental fatigue, cognitive failures and loneliness were the most important variables to predict depression, intolerance to uncertainty and lockdown difficulty were the most important for anxiety, and perceived threat was the most important for predicting lockdown adherence.ConclusionsDuring the extended lockdown, psychological symptoms increased, being enhanced by mental fatigue, cognitive difficulties and financial concerns. We found no evidence of behavioural fatigue. Thus, feeling mentally fatigued is not the same as being behaviourally fatigued.

“Who I Am Now, Is More Me.” An Interview Study of Patients’ Reflections 10 Years After Exhaustion Disorder

Aim: To achieve a deeper understanding of the patient’s perception regarding individual aspects related to the development of exhaustion, hindering and supporting factors in the recovery process, and potential remaining consequences, 7–12 years after receiving an exhaustion disorder diagnosis.Participants and Methods: Twenty patients previously diagnosed with and treated for exhaustion disorder were interviewed 7–12 years after onset of the disease. The semi-structured interviews were transcribed verbatim and analyzed with inductive content analysis.Results: Three main themes with patterns of shared meaning resulted from the analysis: “it’s about who I am,” “becoming a more authentic me,” and “the struggle never ends.” The interviewees described rehabilitation from exhaustion disorder as the start of an important personal development toward a truer and more authentic self-image. They perceived this as an ongoing long-lasting process where learned behavior and thought patterns related to overcommitment and overcompliance needed to be re-evaluated. The results also convey long-term consequences such as cognitive difficulties and reduces energy, uncertainty about one’s own health, and the need to prioritize among one’s relationships.Conclusion: Patients with exhaustion disorder are still struggling with dysfunctional strategies and functional impairments such as cognitive problems which limit their lives, 10 years after receiving their exhaustion disorder diagnosis. While informants describe some positive consequences of ED, the results also emphasize the importance of acknowledging that the patients are embedded in systems of relationships, in working life as well as in family life. This needs to be considered, together with other aspects, when working toward prevention of stress-related mental health problems.

Occupational Risk of Low-Level Blast Exposure and TBI-Related Medical Diagnoses: A Population-Based Epidemiological Investigation (2005–2015)

Because traumatic brain injury (TBI)—most often caused by exposure to high-level blast (HLB)—is a leading cause of medical evacuations of deployed U.S. service members in recent conflicts, researchers seek to identify risk factors for TBI. Previous research using self-reported data has identified low-level blast (LLB) as one such risk factor and suggests an association with susceptibility to and symptoms associated with TBI. This article presents a population-based study of all branches of military service that examines the association between occupational risk for LLB and both clinically diagnosed TBIs—from concussions to severe and penetrating TBIs—and conditions commonly comorbid with concussion. Using archival medical and career records from >2 million service members between 2005–2015, this work demonstrates that occupational risk of LLB is associated with any TBI, mild TBI, moderate TBI, cognitive problems, communication problems, hearing problems, headaches, any behavioral health condition, anxiety, drug abuse/dependence, alcohol abuse/dependence, delirium/dementia, posttraumatic stress disorder, post-concussive syndrome, tinnitus, fatigue, and migraines. Understanding the full scope of the effects of LLB on service members will help ensure the health and readiness of service members and may influence both military policy and clinical practice guidelines for blast-induced injuries.