P-1107 - Anticholinergic side effects of antipsychotic medications

2012 ◽  
Vol 27 ◽  
pp. 1
Author(s):  
M. Ozbilen ◽  
C.E. Adams
1992 ◽  
Vol 15 ◽  
pp. 419B ◽  
Author(s):  
T. KALELIOGLU ◽  
N. ERADAMLAR ◽  
E. KANTARCI ◽  
A. VERIMLI ◽  
L. ALPKAN ◽  
...  

2015 ◽  
Vol 16 (2) ◽  
pp. 117-118 ◽  
Author(s):  
Koji Kamiya ◽  
Yasunari Kamiya ◽  
Haruo Niwa

2019 ◽  
Vol 32 (2) ◽  
pp. e100045 ◽  
Author(s):  
Pradeep Kumar ◽  
Dheerendra Kumar Mishra ◽  
Nimisha Mishra ◽  
Sunil Ahuja ◽  
Gyanendra Raghuvanshi ◽  
...  

Clozapine is an atypical antipsychotic which is described to have higher efficacy among all available antipsychotic medications. Clozapine is reserved especially for resistant schizophrenia due to its side effects. Clozapine-induced metabolic syndrome and hyperglycaemia are common long-term side effects and are responsible for increased mortality in patients with schizophrenia. In this case, a patient with resistant schizophrenia was presented with acute-onset hyperglycaemia and delirium with the use of clozapine within a week. Withdrawal of clozapine in the patient led to the improvement in delirium and hyperglycaemia without the use of any hypoglycaemic agent. This case supports the notion that in certain cases clozapine can induce hyperglycemia through possible direct pathophysiological mechanisms within a shorter time frame.


2009 ◽  
Vol 31 (2) ◽  
pp. 187-189 ◽  
Author(s):  
Masanobu Ito ◽  
Kotaro Hatta ◽  
Koichi Miyakawa ◽  
Heii Arai

2012 ◽  
Vol 1 (7) ◽  
pp. 159-163 ◽  
Author(s):  
John E. Kalachnik

While the rate of tardive dyskinesia (TD) and other extrapyramidal side effects (EPSE) is lower with second generation antipsychotic medications compared to first generation antipsychotic medications, these side effects remain of clinical concern. This paper reviews the basis for the continued concern and the importance of secondary prevention, or early detection, within the primary-secondary-tertiary prevention model. The importance of standardized assessment instruments, education, and training is reviewed. Given the widespread use of antipsychotic drugs, the fact that antipsychotic drugs are the standard of care for several psychiatric conditions (with little indication that the magic bullet is on the immediate horizon to replace current antipsychotic drugs) applied monitoring and the early detection of TD and EPSE takes on added importance.


1985 ◽  
Vol 18 (03) ◽  
pp. 231-234 ◽  
Author(s):  
K. Jeppesen ◽  
H. Fledelius

1989 ◽  
Vol 6 (2) ◽  
pp. 144-147 ◽  
Author(s):  
Marjorie Stokes ◽  
Art O'Connor

AbstractAll deaths occurring in the in-patient population of the Central Mental Hospital during the period 1963 to 1987 inclusive were examined. The death rate during the total period was 11.7 per 1,000 admissions. The suicide rate during the total period was 3.9 per 1,000 admissions – there had been no suicides during the most recent five year period. Although the admission rate has been rising since the mid-1970s, the death rate over the last fifteen years has remained stable.Many of the deaths prior to 1970 were in elderly long stay patients who died from natural causes. Five deaths in young patients are described separately – in two of these anticholinergic side effects of medication may have contibuted to the deaths. Seven suicides occcuring during the study period are described separately – four of these occurred in the months soon after admission.


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