Immune Response to Toxic-Shock-Syndrome Toxin-1 (TSST-1) and to Staphylococcal Enterotoxins A, B and C in Staphylococcus aureus Infections

1989 ◽  
Vol 271 (4) ◽  
pp. 486-492 ◽  
Author(s):  
G. Kunstmann ◽  
E. Schröder ◽  
H. Hasbach ◽  
G. Pulverer
Keyword(s):  
Staphylococcus Aureus ◽  
Immune Response ◽  
Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Staphylococcal Enterotoxins ◽  
Toxic Shock Syndrome Toxin

scholarly journals Use of Multiplex PCR To Detect Classical and Newly Described Pyrogenic Toxin Genes in Staphylococcal Isolates

1999 ◽  
Vol 37 (10) ◽  
pp. 3411-3414 ◽  
Author(s):  
Steven R. Monday ◽  
Gregory A. Bohach
Keyword(s):  
Staphylococcus Aureus ◽  
Multiplex Pcr ◽  
Toxic Shock Syndrome ◽  
Food Poisoning ◽  
Toxic Shock ◽  
Cellular Targets ◽  
Staphylococcal Enterotoxins ◽  
Toxin Genes ◽  
Toxic Shock Syndrome Toxin ◽  
Single Reaction

Staphylococcus aureus may contain one or more genes that encode a variety of immunomodulatory pyrogenic toxins (PTs), including the staphylococcal enterotoxins and toxic shock syndrome toxin (TSST). The PTs interact with several cellular targets to produce disease, such as food poisoning and toxic shock syndrome. At present, nine serologically distinct enterotoxins and one immunoreactive form of TSST have been identified and characterized. As isolates of S. aureus are further assessed, it is anticipated that this number will increase. To facilitate screening, a multiplex PCR was designed to simultaneously determine which of these 10 currently known PT genes an individualS. aureus isolate possesses. We show here, using S. aureus isolates with characterized PT phenotypes, that this novel PCR technique reliably detects each of the known PTs in a single reaction.

Monoclonal Antibodies to the Enterotoxins and to the Toxic Shock Syndrome Toxin Produced by Staphylococcus aureus

1985 ◽  
pp. 23-59 ◽  
Author(s):  
NANCY E. THOMPSON ◽  
MERLIN S. BERGDOLL ◽  
RICHARD F. MEYER ◽  
REGINALD W. BENNETT ◽  
LLONAS MILLER ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Monoclonal Antibodies ◽  
Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Toxic Shock Syndrome Toxin

Regulation of toxic shock syndrome toxin‐1 by the accessory gene regulator in Staphylococcus aureus is mediated by the repressor of toxins

2019 ◽  
Vol 112 (4) ◽  
pp. 1163-1177 ◽  
Author(s):  
Stephen W. Tuffs ◽  
Christine A. Herfst ◽  
Miren L. Baroja ◽  
Vladyslav A. Podskalniy ◽  
Erica N. DeJong ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Toxic Shock Syndrome ◽  
Toxic Shock ◽  
Accessory Gene ◽  
Accessory Gene Regulator ◽  
Toxic Shock Syndrome Toxin
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