The erythrocyte sedimentation reaction, introduced into clinical practice by FahraeuS'OM, has found the greatest application in gynecology. A number of works of German (Fahreus, Linzenmeier, Geppert, Haselhorst, Mahnert, Gnssle; Molnar, Oettinger, etc.) and Russian (Mandelstam, Bronnikova, Popova-Terebinskaya, Izakson, etc.) authors quite established its suitability for clinical purposes, and at present, study of this reaction should pass, as Dr. Bronnikova rightly put it, to the phase of studying various details connected with its application at the patient bedside. In the present report we present the results of our clinical observations made with the help of this reaction in the Obstetric and Gynecologic Clinic of the Kazan Clinical Institute and partly on cancer patients who underwent radiotherapy in the Faculty Obstetric and Gynecologic Clinic of Prof. V.S. Gruzdev.