Background: Diabetes Mellitus is a metabolic disorder in which carbohydrate utilization is reduced and that of lipid and protein enhanced; it is caused by an absolute or relative deficiency of insulin and is characterized by Hyperglycemia. The mortality rate due to Diabetes mellitus is very high and is ranked fifth amongst the ten major causes of death in southern part of India. The prevalence of Diabetes in adults globally was estimated to be 150 million and this figure is expected to double by 2025. Ayurveda has described that a rational treatment is one where the medicine modifies the disease; on the other hand it doesn’t provoke new complaints. Due to all these things it has become a challenge for Ayurvedists to search for an additional safe and effective treatment. Objective: To evaluate the combined effect of Samsamanivati and Darvyadi Kwatha in the management of Madhumeha w.s.r. to type -II Diabetes Mellitus. Method: A 55yr old female patient presenting symptoms of Prabhutmutrarta, Naktamutrata, Trushna, Hastapadadaha, Alasya since two years. Patient was k/c/o DM since 2yrs. Patient was treated with Samsamanivati - 250mg (2 tab) two times a day after meal and Darvyadi Kwatha - 40ml. after meals two times a day for three months.BSL(F) and BSL (PP) was done before and after treatment. Result: The combination of these medicines has also shown highly significant in subjective parameters and moderately significant in objective parameters. Conclusion: Theses selected combination of medicines were found to be highly significant in treating type II Daibetes mellitus.
New-onset type II diabetes mellitus, hyperosmolar non-ketotic coma, rhabdomyolysis and acute renal failure in a patient treated with sulpiride
