scholarly journals Primary hyperparathyroidism with severe bone disease: osteitis fibrosa cystica vs. fibrous dysplasia. Case report and review of the literature

1999 ◽  
Vol 10 (2) ◽  
pp. 120-124
Author(s):  
Maria João Leitão ◽  
Luı́s Cuña ◽  
Nuno Pinheiro ◽  
Vı́tor Coelho ◽  
Mário Oliveira ◽  
...  
2020 ◽  
Vol 48 (10) ◽  
pp. 030006052096648
Author(s):  
Yu Wang ◽  
Jie Liu

Bone disease is an important complication of hyperparathyroidism. We herein report a rare case of severe bone disease caused by primary hyperparathyroidism. A 33-year-old man presented with pain and restricted mobility in his right upper limb and right hip due to a fall 3 days previously. X-ray examination showed a fracture of the proximal and distal humerus. Computed tomography examination showed a supracondylar fracture of the right humerus, a fracture of the right femoral neck, a fracture of the right sciatic branch, and multiple brown tumors. Ultrasonography showed a 3.5- × 1.6-cm hypoechoic mass below the left lobe of the thyroid. The patient was diagnosed with primary hyperparathyroidism based on increased serum calcium and parathormone concentrations, pathological fractures, and multiple brown tumors. He therefore underwent bilateral lower parathyroidectomy. Pathological examination revealed a parathyroid adenoma. The patient recovered well after surgery and was followed up for 6 months with no symptoms of hyperparathyroidism. This case report suggests that clinicians should be aware of the possibility of severe bone disease secondary to primary hyperparathyroidism. Active and early diagnosis and surgical treatment are important in such cases.


Orthopedics ◽  
2001 ◽  
Vol 24 (10) ◽  
pp. 1000-1002
Author(s):  
Treyce S Knee ◽  
Almond J Drake ◽  
David Turton ◽  
K M Mohamed Shakir

Author(s):  
Banu Yigit ◽  
Mert Tanal ◽  
Bulent Citgez

Abstract Brown tumor (BT) is the pathological expression of osteitis fibrosa cystica owing to primary and secondary hyperparathyroidism (HPT). It is a rare benign lesion of skeletal system that usually affects the facial bones, clavicles, ribs, pelvis and extremities. The purpose of this case report is to present the clinical, pathological and radiological findings of BT, rarely seen in adults, originating from the giant parathyroid adenoma and emerging as the first clinical sign of HPT. The patient underwent a successful parathyroidectomy operation and on the first postoperative day, the patient was discharged without any complications. Continuous...


QJM ◽  
2015 ◽  
Vol 108 (12) ◽  
pp. 991-991
Author(s):  
D. Seo ◽  
Y. Rhee

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Anthony M. Maina ◽  
Harry Kraus

Osteitis Fibrosa Cystica (OFC) is defined as the classic skeletal manifestation of advanced primary hyperparathyroidism. With the increased detection by means of routine calcium screening, the clinical profile of primary hyperparathyroidism in Western countries has shifted from symptomatic disease to one with subtle or no specific symptoms (“asymptomatic” primary hyperparathyroidism). The authors describe a classical feature of advanced primary hyperparathyroidism due to a parathyroid adenoma and its successful treatment.


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