Design and synthesis of orally bioavailable inhibitors of inducible nitric oxide synthase. synthesis and biological evaluation of dihydropyridin-2(1H)-imines and 1,5,6,7-Tetrahydro-2H-azepin-2-imines

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(02)00540-0 ◽

2003 ◽

Vol 11 (5) ◽

pp. 689-702 ◽

Author(s):

Yasufumi Kawanaka ◽

Kaoru Kobayashi ◽

Shinya Kusuda ◽

Tadashi Tatsumi ◽

Masayuki Murota ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Design And Synthesis ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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ChemInform Abstract: Design and Synthesis of Orally Bioavailable Inhibitors of Inducible Nitric Oxide Synthase. Part 1. Synthesis and Biological Evaluation of Dihydropyridin-2-imines.

10.1002/chin.200251148 ◽

2010 ◽

Vol 33 (51) ◽

pp. no-no

Author(s):

Yasufumi Kawanaka ◽

et al. et al.

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Design And Synthesis ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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Design and synthesis of orally bioavailable inhibitors of inducible nitric oxide synthase. Part 1: synthesis and biological evaluation of dihydropyridin-2-imines

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(02)00455-9 ◽

2002 ◽

Vol 12 (17) ◽

pp. 2291-2294 ◽

Author(s):

Yasufumi Kawanaka ◽

Kaoru Kobayashi ◽

Shinya Kusuda ◽

Tadashi Tatsumi ◽

Masanori Murota ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Design And Synthesis ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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Synthesis and biological evaluation of inducible nitric oxide synthase inhibitors as anticancer agents

10.3390/ecmc2020-07370 ◽

2020 ◽

Author(s):

Cristina Maccallini

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Anticancer Agents ◽

Biological Evaluation ◽

Nitric Oxide Synthase Inhibitors ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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Design and Synthesis of Orally Bioavailable Inhibitors of Inducible Nitric Oxide Synthase. Identification of 2-Azabicyclo[4.1.0]heptan-3-imines

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(03)00034-8 ◽

2003 ◽

Vol 11 (8) ◽

pp. 1723-1743 ◽

Author(s):

Yasufumi Kawanaka ◽

Kaoru Kobayashi ◽

Shinya Kusuda ◽

Tadashi Tatsumi ◽

Masayuki Murota ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Design And Synthesis ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Inducible Nitric Oxide

Download Full-text

Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB1R Inverse Agonist/Inducible Nitric Oxide Synthase (iNOS) Inhibitors for the Treatment of Liver Fibrosis

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.6b01504 ◽

2017 ◽

Vol 60 (3) ◽

pp. 1126-1141 ◽

Author(s):

Malliga R. Iyer ◽

Resat Cinar ◽

Alexis Katz ◽

Michael Gao ◽

Katalin Erdelyi ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Liver Fibrosis ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Design Synthesis ◽

Inos Inhibitors ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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ChemInform Abstract: Synthesis, Biological Evaluation and Molecular Docking Studies of 3-(Triazolyl)-coumarin Derivatives: Effect on Inducible Nitric Oxide Synthase.

10.1002/chin.201316117 ◽

2013 ◽

Vol 44 (16) ◽

pp. no-no

Author(s):

Helio A. Stefani ◽

et al. et al.

Keyword(s):

Nitric Oxide ◽

Molecular Docking ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Docking Studies ◽

Biological Evaluation ◽

Coumarin Derivatives ◽

Molecular Docking Studies ◽

Oxide Synthase ◽

Inducible Nitric Oxide

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Novel and orally bioavailable inducible nitric oxide synthase inhibitors: synthesis and evaluation of optically active 4,5-dialkyl-2-iminoselenazolidine derivatives

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2005.01.013 ◽

2005 ◽

Vol 15 (5) ◽

pp. 1361-1366 ◽

Author(s):

Shigeo Ueda ◽

Hideo Terauchi ◽

Kenji Suzuki ◽

Akihiro Yano ◽

Masashi Matsumoto ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Optically Active ◽

Nitric Oxide Synthase Inhibitors ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Inducible Nitric Oxide

Download Full-text

Corrigendum to “Novel and orally bioavailable inducible nitric oxide synthase inhibitors: synthesis and evaluation of optically active 4,5-dialkyl-2-iminoselenazolidine derivatives”

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2005.02.008 ◽

2005 ◽

Vol 15 (8) ◽

pp. 2181

Author(s):

Shigeo Ueda ◽

Hideo Terauchi ◽

Kenji Suzuki ◽

Akihiro Yano ◽

Masashi Matsumoto ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Optically Active ◽

Nitric Oxide Synthase Inhibitors ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Inducible Nitric Oxide

Download Full-text

Design and Synthesis of Inhibitors of Inducible Nitric Oxide Synthase. Discovery of a New Chemical Lead with Potential for Oral Bioavailability.

10.1002/chin.200331163 ◽

2003 ◽

Vol 34 (31) ◽

Author(s):

Yasufumi Kawanaka ◽

et al. et al.

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Oral Bioavailability ◽

Design And Synthesis ◽

Oxide Synthase ◽

Inducible Nitric Oxide

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Design and Synthesis of 2-Amino-4-methylpyridine Analogues as Inhibitors for Inducible Nitric Oxide Synthase and in Vivo Evaluation of [18F]6-(2-Fluoropropyl)-4-methyl-pyridin-2-amine as a Potential PET Tracer for Inducible Nitric Oxide Synthase

Journal of Medicinal Chemistry ◽

10.1021/jm801556h ◽

2009 ◽

Vol 52 (8) ◽

pp. 2443-2453 ◽

Author(s):

Dong Zhou ◽

Hsiaoju Lee ◽

Justin M. Rothfuss ◽

Delphine L. Chen ◽

Datta E. Ponde ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

In Vivo Evaluation ◽

Design And Synthesis ◽

Oxide Synthase ◽

Inducible Nitric Oxide

Download Full-text