Synthesis and biological evaluation of inducible nitric oxide synthase inhibitors as anticancer agents

Mapping Intimacies ◽

10.3390/ecmc2020-07370 ◽

2020 ◽

Author(s):

Cristina Maccallini

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Anticancer Agents ◽

Biological Evaluation ◽

Nitric Oxide Synthase Inhibitors ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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ChemInform Abstract: Design and Synthesis of Orally Bioavailable Inhibitors of Inducible Nitric Oxide Synthase. Part 1. Synthesis and Biological Evaluation of Dihydropyridin-2-imines.

10.1002/chin.200251148 ◽

2010 ◽

Vol 33 (51) ◽

pp. no-no

Author(s):

Yasufumi Kawanaka ◽

et al. et al.

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Design And Synthesis ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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Design and synthesis of orally bioavailable inhibitors of inducible nitric oxide synthase. Part 1: synthesis and biological evaluation of dihydropyridin-2-imines

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(02)00455-9 ◽

2002 ◽

Vol 12 (17) ◽

pp. 2291-2294 ◽

Author(s):

Yasufumi Kawanaka ◽

Kaoru Kobayashi ◽

Shinya Kusuda ◽

Tadashi Tatsumi ◽

Masanori Murota ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Design And Synthesis ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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Design and synthesis of orally bioavailable inhibitors of inducible nitric oxide synthase. synthesis and biological evaluation of dihydropyridin-2(1H)-imines and 1,5,6,7-Tetrahydro-2H-azepin-2-imines

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(02)00540-0 ◽

2003 ◽

Vol 11 (5) ◽

pp. 689-702 ◽

Author(s):

Yasufumi Kawanaka ◽

Kaoru Kobayashi ◽

Shinya Kusuda ◽

Tadashi Tatsumi ◽

Masayuki Murota ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Design And Synthesis ◽

Orally Bioavailable ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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Synthesis, structural investigations and biological evaluation of novel hexahydropyridazine-1-carboximidamides, -carbothioamides and -carbothioimidic acid esters as inducible nitric oxide synthase inhibitors

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2003.12.007 ◽

2004 ◽

Vol 12 (5) ◽

pp. 1071-1089 ◽

Author(s):

Olaf Morgenstern ◽

Heike Wanka ◽

Ilka Röser ◽

Antje Steveling ◽

Beate Kuttler

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Structural Investigations ◽

Nitric Oxide Synthase Inhibitors ◽

Oxide Synthase ◽

Acid Esters ◽

Inducible Nitric Oxide

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Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB1R Inverse Agonist/Inducible Nitric Oxide Synthase (iNOS) Inhibitors for the Treatment of Liver Fibrosis

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.6b01504 ◽

2017 ◽

Vol 60 (3) ◽

pp. 1126-1141 ◽

Author(s):

Malliga R. Iyer ◽

Resat Cinar ◽

Alexis Katz ◽

Michael Gao ◽

Katalin Erdelyi ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Liver Fibrosis ◽

Inducible Nitric Oxide Synthase ◽

Biological Evaluation ◽

Design Synthesis ◽

Inos Inhibitors ◽

Oxide Synthase ◽

Synthesis And Biological Evaluation ◽

Inducible Nitric Oxide

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Inducible nitric oxide synthase inhibitors of Chinese herbs. Part 2: Naturally occurring furanocoumarins

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(00)00200-5 ◽

2000 ◽

Vol 8 (12) ◽

pp. 2701-2707 ◽

Author(s):

Ching-Chiung Wang ◽

Jing-Erh Lai ◽

Lih-Geeng Chen ◽

Kun-Ying Yen ◽

Ling-Ling Yang

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Chinese Herbs ◽

Nitric Oxide Synthase Inhibitors ◽

Naturally Occurring ◽

Oxide Synthase ◽

Inducible Nitric Oxide

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Oral Administration of Inducible Nitric Oxide Synthase Inhibitors Reduces Nitric Oxide Synthesis but Has No Effect on the Severity of Experimental Colitis

Scandinavian Journal of Gastroenterology ◽

10.1080/003655200750023200 ◽

2000 ◽

Vol 35 (8) ◽

pp. 832-838 ◽

Author(s):

A. M. Armstrong, G. R. Campbell, C.

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Oral Administration ◽

Inducible Nitric Oxide Synthase ◽

Experimental Colitis ◽

Nitric Oxide Synthesis ◽

Nitric Oxide Synthase Inhibitors ◽

Oxide Synthase ◽

Inducible Nitric Oxide

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Inducible nitric oxide synthase inhibitors prolonged the survival of skin xenografts through selective down-regulation of pro-inflammatory cytokine and CC-chemokine expressions

Transplant Immunology ◽

10.1016/s0966-3274(03)00013-3 ◽

2003 ◽

Vol 12 (1) ◽

pp. 63-72 ◽

Author(s):

Jae Young Kim ◽

Donghee Kim ◽

Eun Mi Lee ◽

Inho Choi ◽

Chung-Gyu Park ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Inflammatory Cytokine ◽

Down Regulation ◽

Cc Chemokine ◽

Nitric Oxide Synthase Inhibitors ◽

Oxide Synthase ◽

Inducible Nitric Oxide

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Prevention of Early Islet Graft Failure by Selective Inducible Nitric Oxide Synthase Inhibitors after Pig to Nude Rat Intraportal Islet Transplantation. Transplantation 2001; 71: 179???184.

Transplantation Journal ◽

10.1097/00007890-200101270-00001 ◽

2001 ◽

Vol 71 (2) ◽

pp. 177-178 ◽

Author(s):

Roger F. L. James

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Islet Transplantation ◽

Inducible Nitric Oxide Synthase ◽

Graft Failure ◽

Islet Graft ◽

Nitric Oxide Synthase Inhibitors ◽

Nude Rat ◽

Oxide Synthase ◽

Inducible Nitric Oxide

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Anmindenols A and B, Inducible Nitric Oxide Synthase Inhibitors from a Marine-Derived Streptomyces sp.

Journal of Natural Products ◽

10.1021/np500285a ◽

2014 ◽

Vol 77 (6) ◽

pp. 1528-1531 ◽

Author(s):

Jihye Lee ◽

Hiyoung Kim ◽

Tae Gu Lee ◽

Inho Yang ◽

Dong Hwan Won ◽

...

Keyword(s):

Nitric Oxide ◽

Nitric Oxide Synthase ◽

Inducible Nitric Oxide Synthase ◽

Streptomyces Sp ◽

Nitric Oxide Synthase Inhibitors ◽

Oxide Synthase ◽

Inducible Nitric Oxide

Download Full-text