UV-A breakage sensitivity of human chromosomes as measured by COMET-FISH depends on gene density and not on the chromosome size

2000 ◽  
Vol 56 (2-3) ◽  
pp. 109-117 ◽  
Author(s):  
Alexander Rapp ◽  
Claudia Bock ◽  
Heike Dittmar ◽  
Karl-Otto Greulich
Keyword(s):  
Gene Density ◽  
Chromosome Size ◽  
Human Chromosomes

Chromosome size, morphology, and gene density determine bivalent positioning in metaphase I human spermatocytes

2014 ◽  
Vol 101 (3) ◽  
pp. 818-824.e3 ◽  
Author(s):  
Laia Vergés ◽  
Joan Blanco ◽  
Oliver Valero ◽  
Francesca Vidal ◽  
Zaida Sarrate
Keyword(s):  
Gene Density ◽  
Chromosome Size ◽  
Metaphase I

Analysis of centromere size in human chromosomes 1, 9, 15, and 16 by electron microscopy

Genome ◽  
1991 ◽  
Vol 34 (5) ◽  
pp. 710-713 ◽  
Author(s):  
Laura Sanchez ◽  
Paulino Martínez ◽  
Vicente Goyanes
Keyword(s):  
Electron Microscopy ◽  
Quantitative Analysis ◽  
Chromosome 9 ◽  
Interindividual Variation ◽  
Pericentromeric Heterochromatin ◽  
Chromosome 15 ◽  
Chromosome Size ◽  
Human Chromosomes ◽  
Positive Correlation ◽  
Whole Mount

Human chromosomes were treated with 5-azacytidine and analyzed by whole-mount electron microscopy. This base analogue produces undercondensation of heterochromatin and separation of the centromere from the bulk of pericentromeric heterochromatin in chromosomes 1, 9, 15, and 16, which allows clear delimitation of the centromere regions. A quantitative analysis of centromeres showed that chromosomes 1, 9, and 16 have centromeres of different size. The centromere of chromosome 15 is similar in size to that of chromosome 9 and different from those of chromosomes 1 and 16. No interindividual variation for centromere size was found. A positive correlation between centromere and chromosome size was found for the chromosomes analyzed.Key words: centromere size, human chromosomes, electron microscopy.

Automatic Karyotyping of Human Chromosomes Using Band Patterns

2012 ◽  
Vol 2 (12) ◽  
pp. 154-156 ◽  
Author(s):  
Priya Chaku ◽  
◽  
Pooja Shah
Keyword(s):  
Human Chromosomes

Linkage of genetic markers on human chromosomes 20 and 12 to NIDDM in Caucasian sib pairs with a history of diabetic nephropathy

Diabetes ◽  
1997 ◽  
Vol 46 (5) ◽  
pp. 882-886 ◽  
Author(s):  
D. W. Bowden ◽  
M. Sale ◽  
T. D. Howard ◽  
A. Qadri ◽  
B. J. Spray ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Genetic Markers ◽  
Human Chromosomes ◽  
History Of ◽  
Sib Pairs
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