905 ROPIVACAINE: EFFICIENT LOCAL ANESTHETIC IN ASSOCIATION WITH MORPHINE AND CLONIDINE FOR TREATMENT OF CANCER PAIN BY INTRATHECAL DRUG DELIVERY SYSTEM

2009 ◽  
Vol 13 (S1) ◽  
Author(s):  
D. Dupoiron ◽  
O. Brenet ◽  
F. Grelon ◽  
S. Bourmont ◽  
L.D. Pierre‐Yves ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Pain ◽  
Drug Delivery System ◽  
Delivery System ◽  
Local Anesthetic ◽  
Intrathecal Drug Delivery

scholarly journals Efficacy of intrathecal drug delivery system for refractory cancer pain patients: A single tertiary medical center experience

2012 ◽  
Vol 111 (5) ◽  
pp. 253-257 ◽  
Author(s):  
Chih-Peng Lin ◽  
Wen-Ying Lin ◽  
Feng-Sheng Lin ◽  
Yow-Shan Lee ◽  
Chuen-Shin Jeng ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Pain ◽  
Drug Delivery System ◽  
Delivery System ◽  
Medical Center ◽  
Intrathecal Drug Delivery ◽  
Pain Patients

Intrathecal Drug Delivery System (IDDS) for Cancer Pain Management

2011 ◽  
Vol 29 (5) ◽  
pp. 388-398 ◽  
Author(s):  
Surjya Prasad Upadhyay ◽  
Piyush N. Mallick
Keyword(s):  
Drug Delivery ◽  
Pain Management ◽  
Cancer Pain ◽  
Drug Delivery System ◽  
Delivery System ◽  
Cancer Pain Management ◽  
Patients With Cancer ◽  
Intrathecal Drug Delivery ◽  
Number Of Patients ◽  
Interventional Pain Management

Cancer pain remains undertreated and a significant number of patients with cancer pain die from severe untreated pain. With increasing survival rate in cancer, the prevalence of cancer pain is also increasing in number. Though majority of patients with cancer pain can be effectively treated with conventional medical management, still a significant portion of patients required some form of interventional pain management techniques. Among the interventional techniques, intrathecal drug delivery is increasingly used in cancer pain management. Our objective of this article is to review literatures and clinical studies on intrathecal drug delivery system (IDDS) in cancer pain management and to provide updates on its use, precautions, contraindications, side effects and its management, socioeconomic consideration, and management of IDDS in difficult or uncommon situations.

Multiple Fibrin Glue Use in a Complicated Case of Postdural Puncture Headache Following Intrathecal Drug Delivery System Placement: A Case Report

2019 ◽  
pp. 77-81
Author(s):  
Matthew Chung
Keyword(s):  
Drug Delivery ◽  
Cerebrospinal Fluid ◽  
Drug Delivery System ◽  
Fibrin Glue ◽  
Delivery System ◽  
Epidural Blood Patch ◽  
Csf Leak ◽  
Postdural Puncture Headache ◽  
Intrathecal Drug Delivery ◽  
Blood Patch

A postdural puncture headache (PDPH) is a well-described complication after implantation of an intrathecal drug delivery system (IDDS). Treatment is typically with supportive management with the occasional need for an epidural blood patch. We describe a case of a patient with refractory muscle spasticity secondary to cerebral palsy that required a baclofen IDDS implantation and subsequently developed a PDPH. After failing conservative therapy as well as an epidural blood patch, the decision was made to attempt an epidural fibrin patch, which transiently improved her headache. Upon return of the patient’s symptoms, computed tomography myelogram demonstrated an extensive cerebrospinal fluid leak with ventral spread into the retroperitoneal space. Using a novel technique, a second epidural fibrin glue patch was administered just adjacent to the IDDS catheter insertion point, which was then successful in resolving her symptoms. Key words: Intrathecal drug delivery system, postdural puncture headache, dural tear, cerebrospinal fluid (CSF) leak, fibrin glue, epidural blood patch

Pontine Hemorrhage Following a Recently Implanted Intrathecal Drug Delivery System

Pain Practice ◽  
2009 ◽  
Vol 9 (4) ◽  
pp. 312-316 ◽  
Author(s):  
David M. Rosenfeld ◽  
Terrence Trentman ◽  
Naresh P. Patel
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Intrathecal Drug Delivery ◽  
Pontine Hemorrhage

scholarly journals Treatment of Refractory Postdural Puncture Headache after Intrathecal Drug Delivery System Implantation with Epidural Blood Patch Procedures: A 20-Year Experience

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Markus A. Bendel ◽  
Susan M. Moeschler ◽  
Wenchun Qu ◽  
Eugerie Hanley ◽  
Stephanie A. Neuman ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Epidural Blood Patch ◽  
Demographic Data ◽  
Success Rates ◽  
Postdural Puncture Headache ◽  
Invasive Treatment ◽  
Intrathecal Drug Delivery ◽  
Blood Patch

A recent publication reported the incidence of postdural puncture headache (PDPH) in conjunction with intrathecal drug delivery system (IDDS) implantation to be nearly 23 percent. Many patients responded to conservative measures but a percentage needed invasive treatment with an epidural blood patch (EBP). There is limited data to describe the technical details, success rates, and complications associated with EBP in this population. This study aims to provide a retrospective report of EBP for patients suffering from PDPH related to IDDS implantation. A chart review established a cohort of patients that required EBP in relation to a PDPH after IDDS implantation. This cohort was evaluated for demographic data as well as details of the EBP including technical procedural data, success rates, and complications. All patients received a trial of conservative therapy. Standard sterile technique and skin preparation were utilized with no infectious complications. The EBP was placed below the level of the IDDS catheter in 94% of procedures. Fluoroscopy was utilized in each case. The mean EBP volume was 18.6 cc and median time of EBP was day 7 after implant. There were no complications associated with EBP. EBP appears to be an effective intervention in this subset of PDPH patients.

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