AbstractPeople with central vision loss (CVL) due to macular degeneration are forced to rely on their residual peripheral vision and often develop a preferred retinal locus (PRL), a region of intact peripheral retina that is used for fixation. At the PRL, visual processing is impaired due to crowding (cluttering of visual objects). The problem of crowding still persists when images are magnified to account for the lower resolution of peripheral vision. We assessed whether anodal transcranial direct stimulation (a-tDCS), a neuro-modulation technique that alters cortical inhibition, would reduce collinear inhibition (an early component of crowding) when applied to the visual cortex in patients with CVL. Our results showed that applying a-tDCS to the visual cortex for 20mins reduced crowding in three patients with CVL and that the effect was sustained for up to 30mins. Sham stimulation delivered in a separate session had no effect. These initial observations mandate further research into the use of a-tDCS to enhance cortical processing of residual retinal input in patients with CVL.
PSS36 COMPARISON OF THE QUALITY OF LIFE IMPACT OF PERIPHERAL VISION LOSS VERSUS CENTRAL VISION LOSS
