334 First-in-human study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of oral cp-724, 714, a selective, small molecule inhibitor of her2 in patients with advanced cancer

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(04)80341-0 ◽

2004 ◽

Vol 2 (8) ◽

pp. 101 ◽

Author(s):

P.N. Munster ◽

A.W. Tolcher ◽

C.D. Britten ◽

K. Gelmon ◽

S. Moulder ◽

...

Keyword(s):

Advanced Cancer ◽

Small Molecule ◽

Human Study ◽

Small Molecule Inhibitor ◽

Pharmacokinetics And Pharmacodynamics ◽

Molecule Inhibitor

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SAT0226 A first-in-human, study of BMS-986165, a selective, potent, allosteric small molecule inhibitor of tyrosine kinase 2

10.1136/annrheumdis-2017-eular.3809 ◽

2017 ◽

Author(s):

I Catlett ◽

U Aras ◽

Y Liu ◽

D Bei ◽

I Girgis ◽

...

Keyword(s):

Tyrosine Kinase ◽

Small Molecule ◽

Human Study ◽

Small Molecule Inhibitor ◽

Tyrosine Kinase 2 ◽

Molecule Inhibitor

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602TiP A first-in-human study of NOV1601 (CHC2014), small-molecule inhibitor of TRK family proteins, in adult patients with solid organ malignancies

Annals of Oncology ◽

10.1016/j.annonc.2020.08.716 ◽

2020 ◽

Vol 31 ◽

pp. S502

Author(s):

T. Yun ◽

Y.W. Moon ◽

S.J. Shin ◽

D-W. Kim ◽

C.H. Yun ◽

...

Keyword(s):

Small Molecule ◽

Human Study ◽

Small Molecule Inhibitor ◽

Adult Patients ◽

Solid Organ ◽

Molecule Inhibitor

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Faculty Opinions recommendation of Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1021658.247635 ◽

2004 ◽

Author(s):

William Kaelin

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Shh Pathway ◽

Molecule Inhibitor

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Faculty Opinions recommendation of Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1025625.322882 ◽

2005 ◽

Author(s):

James Stivers

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

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Faculty Opinions recommendation of Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1033159.375732 ◽

2006 ◽

Author(s):

Berl R Oakley

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor

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Faculty Opinions recommendation of The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1066069.520680 ◽

2007 ◽

Author(s):

Nathanael Gray

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

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Faculty Opinions recommendation of The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1066069.519039 ◽

2007 ◽

Author(s):

Tarun Kapoor

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

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Faculty Opinions recommendation of Identification and characterization of a small molecule inhibitor of formin-mediated actin assembly.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1283961.751061 ◽

2009 ◽

Author(s):

Marie-France Carlier

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Actin Assembly ◽

Molecule Inhibitor ◽

Identification And Characterization

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Faculty Opinions recommendation of Regression of castrate-recurrent prostate cancer by a small-molecule inhibitor of the amino-terminus domain of the androgen receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5059957.4994055 ◽

2010 ◽

Author(s):

Michael Weber ◽

Daniel G Gioeli

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Amino Terminus ◽

Recurrent Prostate Cancer ◽

Molecule Inhibitor

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Faculty Opinions recommendation of A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717957380.793461863 ◽

2012 ◽

Author(s):

Pengbo Zhou ◽

Jeffrey Hannah

Keyword(s):

Multiple Myeloma ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Myeloma Cells ◽

Molecule Inhibitor ◽

Specific Protease ◽

Ubiquitin Specific Protease

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