282 POSTER Preliminary results of a Phase I accelerated dose-escalation, pharmacokinetic and pharmacodynamic study of PF-03814735, an oral Aurora kinase A and B inhibitor, in patients with advanced solid tumors

2008 ◽  
Vol 6 (12) ◽  
pp. 91 ◽  
Author(s):  
P. Schöffski ◽  
H. Dumez ◽  
S.F. Jones ◽  
C. Fowst ◽  
P. Gerletti ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Aurora Kinase ◽  
Advanced Solid Tumors ◽  
Aurora Kinase A ◽  
Preliminary Results ◽  
Pharmacodynamic Study ◽  
Kinase A

scholarly journals Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of ENMD-2076, a Novel Angiogenic and Aurora Kinase Inhibitor, in Patients with Advanced Solid Tumors

2010 ◽  
Vol 17 (4) ◽  
pp. 849-860 ◽  
Author(s):  
Jennifer R. Diamond ◽  
Bruno R. Bastos ◽  
Ryan J. Hansen ◽  
Daniel L. Gustafson ◽  
S. Gail Eckhardt ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Kinase Inhibitor ◽  
Aurora Kinase ◽  
Advanced Solid Tumors ◽  
Aurora Kinase Inhibitor ◽  
Pharmacodynamic Study

A Phase I Dose Escalation and Pharmacodynamic Study of SU5416 (Semaxanib) Combined with Weekly Cisplatin and Irinotecan in Patients with Advanced Solid Tumors

Onkologie ◽  
2013 ◽  
Vol 36 (11) ◽  
pp. 6-6 ◽  
Author(s):  
Ludmila K. Martin ◽  
Tanios Bekaii-Saab ◽  
Derek Serna ◽  
Paul Monk ◽  
Steven K. Clinton ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Dose Escalation ◽  
Advanced Solid Tumors ◽  
Pharmacodynamic Study ◽  
Weekly Cisplatin
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