441 Adult patients with patent atrial septal defect: BNP and cardiopulmonary exercise test in the evaluation of exercise capacity in patients over 30 years of age

This chapter describes how a maximal cardiopulmonary exercise test (CPET) assesses the exercise capacity of an individual. It identifies whether exercise is limited by the heart or lungs, or by another factor. The test can be used to elucidate the cause of symptoms such as breathlessness. By quantifying exercise capacity, a CPET can be used as a tool to plan physical training. Information from a CPET helps quantify the risk of a surgical intervention and is used in planning post-operative care. Performance in a CPET is a predictor of subsequent mortality. A CPET should be preceded by a full clinical history and a thorough clinical examination. The test is best interpreted alongside the results of simple preliminary investigations.

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Atrial septal defect in adults: echocardiography and cardiopulmonary exercise capacity associated with hemodynamics before and after surgical closure

Interactive Cardiovascular and Thoracic Surgery ◽

10.1510/icvts.2004.101451 ◽

2005 ◽

Vol 4 (5) ◽

pp. 488-492 ◽

Cited By ~ 11

Author(s):

E. Suchon

Keyword(s):

Atrial Septal Defect ◽

Exercise Capacity ◽

Septal Defect ◽

Surgical Closure ◽

Cardiopulmonary Exercise ◽

Cardiopulmonary Exercise Capacity ◽

Before And After

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Comparison of Cardiopulmonary Exercise Capacity in Patients with Atrial Septal Defect Treated with Minimally Invasive Cardiac Surgery or Transcatheter Closure

Russian Journal of Cardiology ◽

10.15829/1560-4071-2020-3879 ◽

2020 ◽

Vol 25 (8) ◽

pp. 3879

Author(s):

Hicaz Zencirkiran Agus ◽

Serkan Kahraman ◽

Mehmet Erturk ◽

Burak Onan ◽

Ali Kemal Kalkan ◽

...

Keyword(s):

Cardiac Surgery ◽

Minimally Invasive ◽

Atrial Septal Defect ◽

Exercise Capacity ◽

Septal Defect ◽

Transcatheter Closure ◽

Minimally Invasive Cardiac Surgery ◽

Cardiopulmonary Exercise ◽

Cardiopulmonary Exercise Capacity ◽

Asd Closure

Aim. The main aim of our study was to compare the results of transcatheter atrial septal defect (ASD) closure versus minimally invasive cardiac surgery (MICS) focusing on cardiopulmonary exercise capacity and echocardiographic findings preoperatively and 1 month after defect closure.Material and methods. 54 patients with ASD and finally 43 patients who were followed up were included in the study. 21 patients were in MICS (robotic or endoscopic approach) and 22 patients were in transcatheter closure arm. All patients investigated in detail by transesophageal echocardiography and underwent cardiopulmonary exercise test (CPET). At the end of first month, CPET and transthorasic echocardiography were reperformed.Results. There was significant improvement of physical capacity after 1 month following the transcatheter closure procedure documented by exercise time and VO 2 max. Tricuspid annular plane systolic excursion (TAPSE) and tricuspid lateral annular systolic velocity (Tri S) were not changed. In surgery group right heart diameters declined significantly; but VO 2 max, TAPSE and Tri S significantly decreased.Conclusion. Cardiopulmonary exercise function is increased in transcatheter closure group 1 month after closure and contrary not in MICS group. This may be caused by long recovery time of the right ventricle after surgery. Device closure of ASD is preferable to surgical closure if the anatomy is suitable. However, MICS for ASD closure is safe, with short recovery period and less scarring.

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Impact of Right Ventricular Dilatation in Patients with Atrial Septal Defect

Journal of Interventional Cardiology ◽

10.1155/2020/9509105 ◽

2020 ◽

Vol 2020 ◽

pp. 1-5

Author(s):

Rie Nakayama ◽

Yoichi Takaya ◽

Teiji Akagi ◽

Koji Nakagawa ◽

Nobuhisa Watanabe ◽

...

Keyword(s):

Right Ventricular ◽

Atrial Septal Defect ◽

Exercise Capacity ◽

Septal Defect ◽

Adult Patients ◽

Volume Index ◽

End Diastolic Volume ◽

The Mean ◽

Asd Closure ◽

The Relationship

Objective. The aim of this study was to examine the relationship between right ventricular (RV) volume and exercise capacity in adult patients with atrial septal defect (ASD) and to determine the degree of RV dilatation for transcatheter ASD closure. Background. RV dilatation is an indication of transcatheter ASD closure; however, few studies have reported the clinical significance of RV dilatation. Methods. We enrolled 82 consecutive patients (mean age, 49 ± 18 years; female, 68%) who underwent cardiac magnetic resonance imaging and symptom-limited cardiopulmonary exercise test before ASD closure. The relationship between RV volume and peak oxygen uptake (VO2) was evaluated. Results. The mean RV end-diastolic volume index was 108 ± 27 ml/m2 (range, 46 to 180 ml/m2). The mean peak VO2 was 24 ± 7 ml/min/kg (range, 14 to 48 ml/min/kg), and the mean predicted peak VO2 was 90 ± 23%. There were significant negative relationships of RV end-diastolic volume index with peak VO2 (r = −0.28, p<0.01) and predicted peak VO2 (r = −0.29, p<0.01). The cutoff value of RV end-diastolic volume index <80% of predicted peak VO2 was 120 ml/m2, with the sensitivity of 49% and the specificity of 89%. Conclusions. There was a relationship between RV dilatation and exercise capacity in adult patients with ASD. RV end-diastolic volume index ≥120 ml/m2 was related to the reduction in peak VO2. This criterion of RV dilatation may be valuable for the indication of transcatheter ASD closure.

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