760 The prevalence and incidence of left bundle branch block in ambulant patients with chronic heart failure

2007 ◽  
Vol 6 (1) ◽  
pp. 172-172
Author(s):  
A CLARK
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Left Bundle Branch Block ◽  
Bundle Branch Block

scholarly journals Impact of left bundle branch block on heart rate and its relationship to treatment with ivabradine in chronic heart failure

2013 ◽  
Vol 15 (9) ◽  
pp. 1044-1052 ◽  
Author(s):  
Jan-Christian Reil ◽  
Michele Robertson ◽  
Ian Ford ◽  
Jeffrey Borer ◽  
Michel Komajda ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Chronic Heart Failure ◽  
Left Bundle Branch Block ◽  
Bundle Branch Block

scholarly journals Heart rate reduction after ivabradine might be associated with reverse electrical remodeling in patients with cardiomyopathy and left bundle branch block

2018 ◽  
Vol 46 (11) ◽  
pp. 4825-4828 ◽  
Author(s):  
Andrea Kučerová ◽  
Petr Doškář ◽  
Libor Dujka ◽  
Veronika Lekešová ◽  
Petr Volf ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Left Bundle Branch Block ◽  
Reverse Remodeling ◽  
Electrical Remodeling ◽  
Rate Reduction ◽  
Bundle Branch Block ◽  
Intraventricular Conduction ◽  
Risk Of Death ◽  
Mechanical Remodeling

Left bundle branch block increases the risk of death in patients with chronic heart failure. We herein report four clinical cases of patients with chronic heart failure caused by nonischemic cardiomyopathy with left bundle branch block that occurred when adding ivabradine to optimal medical therapy, resulting in reverse electrical and mechanical remodeling. This phenomenon might be explained by the effect of ivabradine on reverse remodeling of the left ventricle with improvement of intraventricular conduction.

scholarly journals Associations between left bundle branch block with different PR intervals, QRS durations, heart rates and the risk of heart failure: a register-based cohort study using ECG data from the primary care setting

Open Heart ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. e001425
Author(s):  
Marc Meller Søndergaard ◽  
Johannes Riis ◽  
Karoline Willum Bodker ◽  
Steen Møller Hansen ◽  
Jesper Nielsen ◽  
...  
Keyword(s):  
Heart Failure ◽  
Primary Care ◽  
Heart Rate ◽  
Left Bundle Branch Block ◽  
Bundle Branch Block ◽  
Increased Risk ◽  
Pr Interval ◽  
Qrs Duration ◽  
The Impact

AimLeft bundle branch block (LBBB) is associated with an increased risk of heart failure (HF). We assessed the impact of common ECG parameters on this association using large-scale data.Methods and resultsUsing ECGs recorded in a large primary care population from 2001 to 2011, we identified HF-naive patients with a first-time LBBB ECG. We obtained information on sex, age, emigration, medication, diseases and death from Danish registries. We investigated the association between the PR interval, QRS duration, and heart rate and the risk of HF over a 2-year follow-up period using Cox regression analysis.Of 2471 included patients with LBBB, 464 (18.8%) developed HF during follow-up. A significant interaction was found between QRS duration and heart rate (p<0.01), and the analyses were stratified on these parameters. Using a QRS duration <150 ms and a heart rate <70 beats per minute (bpm) as the reference, all groups were statistically significantly associated with the development of HF. Patients with a QRS duration ≥150 ms and heart rate ≥70 bpm had the highest risk of developing HF (HR 3.17 (95% CI 2.41 to 4.18, p<0.001). There was no association between the PR interval and HF after adjustment.ConclusionProlonged QRS duration and higher heart rate were associated with increased risk of HF among primary care patients with LBBB, while no association was observed with PR interval. Patients with LBBB with both a prolonged QRS duration (≥150 ms) and higher heart rate (≥70 bpm) have the highest risk of developing HF.

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