scholarly journals Transition of lung function from infants to children with cystic fibrosis (CF), evaluated by whole-body plethysmography

2010 ◽  
Vol 9 ◽  
pp. S57
Author(s):  
R. Kraemer ◽  
C. Cripe-Mamie ◽  
W. Tennhoff ◽  
U. Bühlmann ◽  
S. Gallati
Keyword(s):  
Cystic Fibrosis ◽  
Lung Function ◽  
Whole Body ◽  
Body Plethysmography ◽  
Whole Body Plethysmography

scholarly journals Utility and validity of dynamic chest radiography in cystic fibrosis (dynamic CF): an observational, non-controlled, non-randomised, single-centre, prospective study

2020 ◽  
Vol 7 (1) ◽  
pp. e000569
Author(s):  
Thomas Simon FitzMaurice ◽  
Paul Stephen McNamara ◽  
Dilip Nazareth ◽  
Caroline McCann ◽  
Ram Bedi ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Prospective Study ◽  
Chest Radiography ◽  
Whole Body ◽  
Standards Of Care ◽  
Body Plethysmography ◽  
Single Centre ◽  
Lung Volumes ◽  
Rapid Acquisition ◽  
Whole Body Plethysmography

IntroductionDynamic chest radiography (DCR) uses novel, low-dose radiographic technology to capture images of the thoracic cavity while in motion. Pulmonary function testing is important in cystic fibrosis (CF). The tolerability, rapid acquisition and lower radiation and cost compared with CT imaging may make DCR a useful adjunct to current standards of care.Methods and analysisThis is an observational, non-controlled, non-randomised, single-centre, prospective study. This study is conducted at the Liverpool Heart and Chest Hospital (LHCH) adult CF unit. Participants are adults with CF. This study reviews DCR taken during routine CF Annual Review (n=150), validates DCR-derived lung volumes against whole body plethysmography (n=20) and examines DCR at the start and end of pulmonary exacerbations of CF (n=20). The primary objectives of this study are to examine if DCR provides lung function information that correlates with PFT, and lung volumes that correlate whole body plethysmography.Ethics and disseminationThis study has received the following approvals: HRA REC (11 December 2019) and LHCH R&I (11 October 2019). Results are made available to people with CF, the funders and other researchers. Processed, anonymised data are available from the research team on request.Trial registration numberISRCTN 64994816.

scholarly journals Can the single-breath helium dilution method predict lung volumes as measured by whole-body plethysmography?

2013 ◽  
Vol 39 (6) ◽  
pp. 675-685 ◽  
Author(s):  
Patrícia Chaves Coertjens ◽  
Marli Maria Knorst ◽  
Anelise Dumke ◽  
Adriane Schmidt Pasqualoto ◽  
João Riboldi ◽  
...  
Keyword(s):  
Lung Function ◽  
Whole Body ◽  
Normal Lung ◽  
Regression Equations ◽  
Body Plethysmography ◽  
Lung Volumes ◽  
Single Breath ◽  
Normal Lung Function ◽  
Helium Dilution ◽  
Whole Body Plethysmography

OBJECTIVE: To compare TLC and RV values obtained by the single-breath helium dilution (SBHD) method with those obtained by whole-body plethysmography (WBP) in patients with normal lung function, patients with obstructive lung disease (OLD), and patients with restrictive lung disease (RLD), varying in severity, and to devise equations to estimate the SBHD results.METHODS: This was a retrospective cross-sectional study involving 169 individuals, of whom 93 and 49 presented with OLD and RLD, respectively, the remaining 27 having normal lung function. All patients underwent spirometry and lung volume measurement by both methods.RESULTS: TLC and RV were higher by WBP than by SBHD. The discrepancy between the methods was more pronounced in the OLD group, correlating with the severity of airflow obstruction. In the OLD group, the correlation coefficient of the comparison between the two methods was 0.57 and 0.56 for TLC and RV, respectively (p < 0.001 for both). We used regression equations, adjusted for the groups studied, in order to predict the WBP values of TLC and RV, using the corresponding SBHD values. It was possible to create regression equations to predict differences in TLC and RV between the two methods only for the OLD group. The TLC and RV equations were, respectively, ∆TLCWBP-SBHD in L = 5.264 − 0.060 × FEV1/FVC (r2= 0.33; adjusted r2 = 0.32) and ∆RVWBP-SBHD in L = 4.862 − 0.055 × FEV1/FVC (r2= 0.31; adjusted r2 = 0.30).CONCLUSIONS: The correction of TLC and RV results obtained by SBHD can improve the accuracy of this method for assessing lung volumes in patients with OLD. However, additional studies are needed in order to validate these equations.

Measurement of respiratory function by whole body plethysmography in unanesthetized and unrestrained monkeys

2008 ◽  
Vol 58 (2) ◽  
pp. 173
Author(s):  
Kazuaki Sasaki ◽  
Y. Nakamura ◽  
H. Iizuka ◽  
M. Imaizumi ◽  
H. Atai
Keyword(s):  
Respiratory Function ◽  
Whole Body ◽  
Body Plethysmography ◽  
Whole Body Plethysmography

Whole-body plethysmography

2005 ◽  
pp. 15-43 ◽  
Author(s):  
M.D. Goldman ◽  
H.J. Smith ◽  
W.T. Ulmer
Keyword(s):  
Whole Body ◽  
Body Plethysmography ◽  
Whole Body Plethysmography

scholarly journals Measuring Breathing Patterns in Mice Using Whole-body Plethysmography

BIO-PROTOCOL ◽  
2020 ◽  
Vol 10 (17) ◽  
Author(s):  
Patricia Prada-Dacasa ◽  
Andrea Urpi ◽  
Laura Sánchez-Benito ◽  
Patrizia Bianchi ◽  
Albert Quintana
Keyword(s):  
Whole Body ◽  
Body Plethysmography ◽  
Breathing Patterns ◽  
Whole Body Plethysmography

scholarly journals Whole body plethysmography measurement of respiratory function of mice in vivo (1178.9)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
John Quindry ◽  
Christopher Ballmann ◽  
Joshua Selsby
Keyword(s):  
Respiratory Function ◽  
Whole Body ◽  
Body Plethysmography ◽  
Whole Body Plethysmography

Maturation of baseline breathing and of hypercapnic and hypoxic ventilatory responses in newborn mice

2001 ◽  
Vol 281 (5) ◽  
pp. R1746-R1753 ◽  
Author(s):  
Sylvain Renolleau ◽  
Stéphane Dauger ◽  
Fanny Autret ◽  
Guy Vardon ◽  
Claude Gaultier ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Tidal Volume ◽  
Mammalian Species ◽  
Whole Body ◽  
Body Plethysmography ◽  
Genetic Studies ◽  
Newborn Mice ◽  
Ventilatory Responses ◽  
Neuronal Mechanisms ◽  
Whole Body Plethysmography

Breathing during the first postnatal hours has not been examined in mice, the preferred mammalian species for genetic studies. We used whole body plethysmography to measure ventilation (V˙e), breath duration (TTOT), and tidal volume (Vt) in mice delivered vaginally (VD) or by cesarean section (CS). In experiment 1, 101 VD and 100 CS pups aged 1, 6, 12, 24, or 48 h were exposed to 8% CO2 or 10% O2for 90 s. In experiment 2, 31 VD pups aged 1, 12, or 24 h were exposed to 10% O2 for 5 min. Baseline breathing maturation was delayed in CS pups, but V˙eresponses to hypercapnia and hypoxia were not significantly different between VD and CS pups [at postnatal age of 1 h (H1): 48 ± 44 and 18 ± 32%, respectively, in VD and CS pups combined]. TheV˙e increase induced by hypoxia was greater at H12 (46 ± 27%) because of TTOT response maturation. At all ages, hypoxic decline was ascribable mainly to a Vtdecrease, and posthypoxic decline was ascribable to a TTOTincrease with apneas, suggesting different underlying neuronal mechanisms.

Effects of cadmium chloride inhalation on airflow limitation to histamine, carbachol and adenosine 5′-monophosphate assessed by barometric whole body plethysmography in healthy dogs

2007 ◽  
Vol 173 (1) ◽  
pp. 62-72 ◽  
Author(s):  
Reinhard A. Hirt ◽  
Katerina Vondrakova ◽  
Abigail Guija de Arespacochaga ◽  
Andrea Gütl ◽  
René van den Hoven
Keyword(s):  
Cadmium Chloride ◽  
Airflow Limitation ◽  
Whole Body ◽  
Body Plethysmography ◽  
Healthy Dogs ◽  
Whole Body Plethysmography

scholarly journals Early and late allergic reaction in the nose assessed by whole body plethysmography

1996 ◽  
Vol 9 (8) ◽  
pp. 1701-1706 ◽  
Author(s):  
M.S. de Bruin-Weller ◽  
F.R. Weller ◽  
A. Scholte ◽  
L.H.M. Rijssenbeek ◽  
S. van der Baan ◽  
...  
Keyword(s):  
Allergic Reaction ◽  
Whole Body ◽  
Body Plethysmography ◽  
Whole Body Plethysmography
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