The effect of BCG and mitomycin C instillation treatment in recurrent superficial bladder carcinoma. 15-year follow-up of a randomised prospective finn bladder study

2002 ◽  
Vol 1 (1) ◽  
pp. 101
Author(s):  
Lauri Taipale ◽  
Jaakko Permi ◽  
Jouko Viitanen ◽  
Heikki Korhonen ◽  
Harri Juusela ◽  
...  
Keyword(s):  
Mitomycin C ◽  
Bladder Carcinoma ◽  
Superficial Bladder Carcinoma

scholarly journals Bladder perforation after immediate postoperative intravesical instillation of mitomycin C

2013 ◽  
Vol 4 (1) ◽  
pp. 1 ◽  
Author(s):  
Darwin Lim ◽  
Jonathan I. Izawa ◽  
Paul Middlebrook ◽  
Joseph L. Chin
Keyword(s):  
Intensive Care ◽  
Single Dose ◽  
Mitomycin C ◽  
Male Patient ◽  
Transurethral Resection ◽  
Bladder Carcinoma ◽  
Adjunctive Therapy ◽  
Intravesical Instillation ◽  
Recurrence Rates ◽  
Superficial Bladder Carcinoma

Intravesical chemotherapy after transurethral resection of a bladdertumour (TURBT) has been observed to significantly decreaserecurrence rates compared to TURBT alone. Though immediatepostoperative intravesical treatment with chemotherapeutic agentsafter transurethral resection for superficial bladder carcinoma isgenerally considered a safe and effective adjunctive therapy indecreasing recurrence rates, its instillation is not always completelyinnocuous. Lately, a more serious complication of bladderperforation associated with immediate instillation of intravesicalmitomycin C (MMC) after TURBT was reported. We reportour own experience of a male patient with bladder perforationafter an early instillation of a single dose of MMC. In this case,systemic toxicity occurred which required intensive care aftersurgical repair.

Long-Term Follow-Up of Cytostatic Intravesical Instillation in Patients with Superficial Bladder Carcinoma

1997 ◽  
Vol 31 (2) ◽  
pp. 153-159 ◽  
Author(s):  
Hartwig Schwaibold ◽  
Uwe Pichlmeier ◽  
Hans-Jörg Klingenberger ◽  
Hartwig Huland
Keyword(s):  
Bladder Carcinoma ◽  
Intravesical Instillation ◽  
Superficial Bladder Carcinoma ◽  
Long Term Follow Up

A phase-1 study of sequential mitomycin C and 5-aminolaevulinic acid-mediated photodynamic therapy in recurrent superficial bladder carcinoma

2005 ◽  
Vol 95 (9) ◽  
pp. 1206-1210 ◽  
Author(s):  
Rob J. Skyrme ◽  
A. Jane French ◽  
Shibendra N. Datta ◽  
Richard Allman ◽  
Malcolm D. Mason ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Mitomycin C ◽  
Bladder Carcinoma ◽  
Phase 1 ◽  
Phase 1 Study ◽  
Aminolaevulinic Acid ◽  
Superficial Bladder Carcinoma

scholarly journals Microsatellite analysis?DNA test in urine competes with cystoscopy in follow-up of superficial bladder carcinoma

Cancer ◽  
2001 ◽  
Vol 92 (4) ◽  
pp. 768-775 ◽  
Author(s):  
Bas W. G. van Rhijn ◽  
Irene Lurkin ◽  
Wim J. Kirkels ◽  
Theodorus H. van der Kwast ◽  
Ellen C. Zwarthoff
Keyword(s):  
Bladder Carcinoma ◽  
Microsatellite Analysis ◽  
Dna Test ◽  
Superficial Bladder Carcinoma

Determination of a New Cut-Off Value for the Urinary BTAtrak to Optimize the Detection of Recurrences in the Follow-Up of Patients with Superficial Bladder Carcinoma

2007 ◽  
Vol 1 (1) ◽  
pp. 42-47
Author(s):  
Jesus Fernandez-Gomez ◽  
Juan J Rodriguez-Martinez ◽  
Safwan Escaf ◽  
Jorge Garcia-Rodriguez ◽  
Roberto Gonzalez ◽  
...  
Keyword(s):  
Bladder Carcinoma ◽  
Superficial Bladder Carcinoma

Treatment of bladder carcinoma in situ with mitomycin C: long-term follow-up

1994 ◽  
Vol 26 (4) ◽  
pp. 437-442 ◽  
Author(s):  
R. Minervini ◽  
R. Felipetto ◽  
L. Vigano ◽  
M. Cecchi
Keyword(s):  
Mitomycin C ◽  
Bladder Carcinoma ◽  
Carcinoma In Situ ◽  
Long Term Follow Up

scholarly journals Recurrences of Superficial Bladder Carcinoma are Associated with a Raise of CD8high>CD57+ and CD8low T Lymphocytes in Peripheral Blood

2010 ◽  
Vol 3 (1) ◽  
pp. 8-14 ◽  
Author(s):  
John J.L. Jacobs ◽  
Dainius Characiejus ◽  
Vita Pašukonienė ◽  
Feliksas Jankevičius ◽  
R. Jeroen A. Van Moorselaar ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Bladder Carcinoma ◽  
Peripheral Blood ◽  
Interleukin 2 ◽  
Peripheral Blood Leukocyte ◽  
Immunological Parameters ◽  
Cell Counts ◽  
Superficial Bladder Carcinoma ◽  
Blood Leukocyte

Immunotherapy with BCG is effective in patients with recurrent superficial bladder carcinoma. This therapy involves Interleukin-2 (IL-2), but little is known about the immunological parameters involved in superficial bladder carcinoma. We have monitored immunological parameters in twenty patients with superficial bladder carcinoma treated with transurethral resection (TUR) followed by IL-2 instillation. Cell numbers of peripheral blood leukocyte subpopulations were counted before surgery and during follow-up after surgery. During follow-up, we compared the cell counts in patients with and without a recurrent tumour. We used the values of healthy matched controls as a reference. Recurrent disease in patients corresponded with a significant increase in CD8+ lymphocytes, and especially the CD8highCD57+ and CD8low subpopulations. The phenotype of these T lymphocytes belongs to cells with an immunosuppressive function. We hypothesize that these peripheral immune suppressive cells facilitate tumour recurrences or that tumour recurrences cause an increase in peripheral immune suppressive lymphocytes.

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