A phase-1 study of sequential mitomycin C and 5-aminolaevulinic acid-mediated photodynamic therapy in recurrent superficial bladder carcinoma

2005 ◽  
Vol 95 (9) ◽  
pp. 1206-1210 ◽  
Author(s):  
Rob J. Skyrme ◽  
A. Jane French ◽  
Shibendra N. Datta ◽  
Richard Allman ◽  
Malcolm D. Mason ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Mitomycin C ◽  
Bladder Carcinoma ◽  
Phase 1 ◽  
Phase 1 Study ◽  
Aminolaevulinic Acid ◽  
Superficial Bladder Carcinoma

scholarly journals Bladder perforation after immediate postoperative intravesical instillation of mitomycin C

2013 ◽  
Vol 4 (1) ◽  
pp. 1 ◽  
Author(s):  
Darwin Lim ◽  
Jonathan I. Izawa ◽  
Paul Middlebrook ◽  
Joseph L. Chin
Keyword(s):  
Intensive Care ◽  
Single Dose ◽  
Mitomycin C ◽  
Male Patient ◽  
Transurethral Resection ◽  
Bladder Carcinoma ◽  
Adjunctive Therapy ◽  
Intravesical Instillation ◽  
Recurrence Rates ◽  
Superficial Bladder Carcinoma

Intravesical chemotherapy after transurethral resection of a bladdertumour (TURBT) has been observed to significantly decreaserecurrence rates compared to TURBT alone. Though immediatepostoperative intravesical treatment with chemotherapeutic agentsafter transurethral resection for superficial bladder carcinoma isgenerally considered a safe and effective adjunctive therapy indecreasing recurrence rates, its instillation is not always completelyinnocuous. Lately, a more serious complication of bladderperforation associated with immediate instillation of intravesicalmitomycin C (MMC) after TURBT was reported. We reportour own experience of a male patient with bladder perforationafter an early instillation of a single dose of MMC. In this case,systemic toxicity occurred which required intensive care aftersurgical repair.

scholarly journals Pegylated liposomal mitomycin C prodrug enhances tolerance of mitomycin C: a phase 1 study in advanced solid tumor patients

2015 ◽  
Vol 4 (10) ◽  
pp. 1472-1483 ◽  
Author(s):  
Talia Golan ◽  
Tal Grenader ◽  
Patricia Ohana ◽  
Yasmine Amitay ◽  
Hilary Shmeeda ◽  
...  
Keyword(s):  
Mitomycin C ◽  
Solid Tumor ◽  
Phase 1 ◽  
Advanced Solid Tumor ◽  
Tumor Patients ◽  
Phase 1 Study

Pharmacokinetics of BW12C and mitomycin C, given in combination in a phase 1 study in patients with advanced gastrointestinal cancer

1993 ◽  
Vol 32 (1) ◽  
pp. 67-72 ◽  
Author(s):  
Ian F. Dennis ◽  
Jonathan R. S. Ramsay ◽  
Paul Workman ◽  
Norman M. Bleehen
Keyword(s):  
Mitomycin C ◽  
Gastrointestinal Cancer ◽  
Phase 1 ◽  
Phase 1 Study

5-YEAR FOLLOWUP OF A RANDOMIZED PROSPECTIVE STUDY COMPARING MITOMYCIN C AND BACILLUS CALMETTE-GUERIN IN PATIENTS WITH SUPERFICIAL BLADDER CARCINOMA

1999 ◽  
Vol 161 (4) ◽  
pp. 1124-1127 ◽  
Author(s):  
PER-UNO MALMSTROM ◽  
HANS WIJKSTROM ◽  
CARL LUNDHOLM ◽  
KENNETH WESTER ◽  
CHRISTER BUSCH ◽  
...  
Keyword(s):  
Prospective Study ◽  
Mitomycin C ◽  
Bladder Carcinoma ◽  
Bacillus Calmette Guerin ◽  
Superficial Bladder Carcinoma
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