Validation of TNF-α as the top upstream regulator of bladder remodelling during outlet obstruction-induced lower urinary tract dysfunction

2017 ◽  
Vol 16 (3) ◽  
pp. e352
Author(s):  
I. Koeck ◽  
A. Hashemi Gheinani ◽  
F. Burkhard ◽  
K. Monastyrskaya
Keyword(s):  
Urinary Tract ◽  
Lower Urinary Tract ◽  
Outlet Obstruction ◽  
Lower Urinary Tract Dysfunction ◽  
Upstream Regulator ◽  
Tnf Α ◽  
Lower Urinary

scholarly journals Voiding dysfunction and urodynamic abnormalities in elderly patients

2004 ◽  
Vol 59 (4) ◽  
pp. 206-215 ◽  
Author(s):  
Cristiano M. Gomes ◽  
Sami Arap ◽  
Flávio E. Trigo-Rocha
Keyword(s):  
Urinary Tract ◽  
Elderly Patients ◽  
Lower Urinary Tract ◽  
Outlet Obstruction ◽  
The Elderly ◽  
Lower Urinary Tract Dysfunction ◽  
Clinical Aspects ◽  
Functional Impairments ◽  
Detrusor Contractility ◽  
Lower Urinary

Lower urinary tract dysfunction is a major cause of morbidity and decreased quality of life in elderly men and women. With the progressive aging of the population, it is important to understand common micturitional disorders that may occur in this population. Most urinary problems in the elderly are multifactorial in origin, demanding a comprehensive assessment of the lower urinary tract organs, functional impairments, and concurrent medical diseases. Urodynamics is a highly valuable tool in the investigation of elderly patients with lower urinary tract symptoms. Urodynamic tests are not always necessary, being indicated after excluding potentially reversible conditions outside the urinary tract that may be causing or contributing to the symptoms. Although urodynamic tests may reveal common diagnoses such as bladder outlet obstruction and stress urinary incontinence in the elderly population, findings such as detrusor overactivity and impaired detrusor contractility are common and have important prognostic and therapeutic implications. The purpose of this article is to describe common urologic problems in the elderly and review the indications for and clinical aspects of urodynamic studies in these conditions.

996 MicroRNA biomarkers of urodynamically-defined states of bladder outlet obstruction-induced lower urinary tract dysfunction

2016 ◽  
Vol 15 (3) ◽  
pp. e996
Author(s):  
A. Hashemi Gheinani ◽  
F.C. Burkhard ◽  
H. Rehrauer ◽  
C. Aquino Fournier ◽  
I. Keller ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Bladder Outlet Obstruction ◽  
Lower Urinary Tract ◽  
Outlet Obstruction ◽  
Lower Urinary Tract Dysfunction ◽  
Lower Urinary
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