Optimisation of a patient-derived prostate cancer tissue culture model using fresh surgical biopsies to determine patient response to pan-EGFR inhibitor sapitinib

2018 ◽  
Vol 17 (10) ◽  
pp. e2519
Author(s):  
B. McCullough ◽  
C.N. Robson ◽  
S.R. Mccracken
SpringerPlus ◽  
2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Claire Morgan ◽  
Paul D Lewis ◽  
Lynda Hopkins ◽  
Stephanie Burnell ◽  
Howard Kynaston ◽  
...  

2017 ◽  
Vol 56 (31) ◽  
pp. 8992-8997 ◽  
Author(s):  
David R. Spiciarich ◽  
Rosalie Nolley ◽  
Sophia L. Maund ◽  
Sean C. Purcell ◽  
Jason Herschel ◽  
...  

2009 ◽  
Vol 34 (5) ◽  
pp. 643-650 ◽  
Author(s):  
H. OMAE ◽  
C. ZHAO ◽  
Y.-L. SUN ◽  
M. E. ZOBITZ ◽  
S. L. MORAN ◽  
...  

The purpose of this study was to assess tendon metabolism and suture pull-out strength after simple tendon suture in a tissue culture model. One hundred and twelve flexor digitorum profundus tendons from 28 dogs were cultured for 7, 14, or 21 days with or without a static tensile load. In both groups increased levels of matrix metalloproteinase (MMP) mRNA was noted. Suture pull-out strength did not decrease during tissue culture. While the presence of a static load had no effect on the pull-out strength, it did affect MMP mRNA expression. This tissue culture model could be useful in studying the effect of factors on the tendon-suture interface.


2011 ◽  
Vol 10 (2) ◽  
pp. 141
Author(s):  
S. Minner ◽  
M.C. Tsourlakis ◽  
J. Müller ◽  
L. Burkhardt ◽  
P. Tennstedt ◽  
...  

2012 ◽  
Vol 18 (3) ◽  
pp. 663-668 ◽  
Author(s):  
Luca Carmignani ◽  
Stefano Picozzi ◽  
Stefano Casellato ◽  
Giorgio Bozzini ◽  
Carlo Marenghi ◽  
...  

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
Author(s):  
Andrew J. Symes ◽  
Marte Eilertsen ◽  
Michael Millar ◽  
Joseph Nariculam ◽  
Alex Freeman ◽  
...  

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