Correlation of renal scarring to urinary tract infections and vesicoureteral reflux in children

2019 ◽  
Vol 18 (1) ◽  
pp. e416
Author(s):  
H. Aboutaleb ◽  
T.A. Ali ◽  
H. El-Hagrasi ◽  
M.A. El Gohary
Keyword(s):  
Urinary Tract ◽  
Vesicoureteral Reflux ◽  
Urinary Tract Infections ◽  
Renal Scarring ◽  
Tract Infections

scholarly journals The role of voiding cystourethrography in the investigation of children with urinary tract infections

2016 ◽  
Vol 10 (5-6) ◽  
pp. 210 ◽  
Author(s):  
Linda C. Lee ◽  
Armando J. Lorenzo ◽  
Martin A. Koyle
Keyword(s):  
Urinary Tract ◽  
Vesicoureteral Reflux ◽  
Urinary Tract Infections ◽  
Renal Scarring ◽  
High Rate ◽  
Voiding Cystourethrography ◽  
Low Grade ◽  
Endoscopic Injection ◽  
Febrile Uti ◽  
Tract Infections

Urinary tract infections (UTIs) represent a common bacterial cause of febrile illness in children. Of children presenting with a febrile UTI, 25‒40% are found to have vesicoureteral reflux (VUR). Historically, the concern regarding VUR was that it could lead to recurrent pyelonephritis, renal scarring, hypertension, and chronic kidney disease. As a result, many children underwent invasive surgical procedures to correct VUR. We now know that many cases of VUR are low-grade and have a high rate of spontaneous resolution. The roles of surveillance, antibiotic prophylaxis, endoscopic injection, and ureteral reimplantation surgery also continue to evolve. In turn, these factors have influenced the investigation of febrile UTIs.Voiding cystourethrography (VCUG) is the radiographic test of choice to diagnose VUR. Due to its invasive nature and questionable benefit in many cases, the American Academy of Pediatrics (AAP) no longer recommends VCUG routinely after an initial febrile UTI. Nevertheless, these guidelines pre-date the landmark Randomized Intervention of Children with Vesicoureteral Reflux (RIVUR) trial and there continues to be controversy regarding the diagnosis and management of VUR. This paper discusses the current literature regarding radiographic testing in children with febrile UTIs and presents a practical risk-based approach for deciding when to obtain a VCUG.

scholarly journals Frequency of Vesicoureteral Reflux in Children having Recurrent Urinary Tract Infections

Esculapio ◽  
2021 ◽  
Vol 16 (4 (oct 2020 - dec 2020)) ◽  
Author(s):  
Irum Aslam ◽  
Muhammad Asif Siddiqui ◽  
Fatima Zia ◽  
Hafsa Qamar
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Vesicoureteral Reflux ◽  
Urinary Tract Infections ◽  
Renal Scarring ◽  
P Value ◽  
Recurrent Urinary Tract Infections ◽  
The Mean ◽  
Tract Infections

Objective: Repeated urinary tract infections are significantly related to anatomical abnormalities of urinary tract. Vesicoureteral reflux is quite common, under diagnosed anatomical abnormality, leads to renal scarring and chronic kidney disease. The objective of the study was to determine the frequency of vesicoureteral reflux in children having repeated urinary tract infections. Methods: It is cross sectional survey conducted in department of Pediatric Medicine, The Children's Hospital & Institute of Child Health, Lahore, spanning from 20-5-2014 to 19-11-2014, using non-probability purposive sampling, a total of 140 patients included. Each child was screened and followed with repeated urinary tract infections for frequency of vesicoureteral reflux by detailed clinical examination and relevant investigation as defined in operational definition. To avoid any controversy, all the findings of UTI & vesicoureteral reflux was assessed by a single consultant. Data was managed using SPSS version 20. Results: In this study the mean age of all patients was 5.64±2.35 years. There were 42 (30%) males and 98(70%) females in this study with male to female ration 1:233. The mean number of episodes of urinary tract infections was 5.82±1.95 per years. Frequency of vesicoureteral reflux in these patients was seen in 35(25%) of the patients. When we stratified the data over age, gender and number of episodes of urinary tract infection we found significant association of vesicoureteral reflux with age groups only (p-value < 0.05) while no association between vesicoureteral reflux versus gender and number of episodes of urinary tract infection (p- value > 0.05). Conclusion: We found significant correlation between vesicoureteral reflux and repeated urinary tract infections. Cases with repeated urinary tract infections should be investigated thoroughly to address underlying cause, in order to prevent renal damage and long-term complications. Key Words: Paediatric, Urinary tract infections, hydronephrosis, Vesicoureteral reflux How to Cite: Aslam I, Siddiqui MA, Zia F, Qamar H. Frequency of vesicoureteral reflux in children having recurrent urinary tract infections. Esculapio.2020;16(04):18-20.

scholarly journals Treatment of recurrent complicated urinary tract infections in children with vesicoureteral reflux

2016 ◽  
Vol 49 (5) ◽  
pp. 717-722 ◽  
Author(s):  
Tsung-Hua Wu ◽  
Fang-Liang Huang ◽  
Lin-Shien Fu ◽  
Chia-Man Chou ◽  
Ya-Li Chien ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Vesicoureteral Reflux ◽  
Urinary Tract Infections ◽  
Tract Infections

185 Urine cytokines profile in women with recurrent urinary tract infections and renal scarring

2012 ◽  
Vol 11 (1) ◽  
pp. e185
Author(s):  
N.M. Stepanova ◽  
V.E. Driyanska ◽  
V.Y. Kundin ◽  
O.A. Romanenko ◽  
T.I. Berezyak
Keyword(s):  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Renal Scarring ◽  
Recurrent Urinary Tract Infections ◽  
Tract Infections

scholarly journals Posttransplantation Vesicoureteral Reflux in Renal Grafts and Their Outcomes in Pediatric Transplantation: Should We Be Afraid ?

2021 ◽  
Author(s):  
Demet Alaygut ◽  
Eren Soyaltın ◽  
Elif Perihan Öncel ◽  
İsmail Sert ◽  
Cem Tuğmen ◽  
...  
Keyword(s):  
Urinary Tract ◽  
Vesicoureteral Reflux ◽  
Urinary Tract Infections ◽  
Bladder Capacity ◽  
Voiding Cystourethrography ◽  
Post Transplantation ◽  
Renal Graft ◽  
Recurrent Urinary Tract Infections ◽  
Tract Infections ◽  
Special Assessment

Objective: Demographical, pre-transplantation and post-transplantation features and post-treatment results of four pediatric cases, who had vesicoureteral reflux (VUR) in the graft kidney, were discussed. Methods: Transplantation age, primary diagnosis, VUR to pretransplantation in native kidneys, history of bladder dysfunction, bladder capacity, results of urodynamic studies, donor and its features, induction treatments and ongoing immunosuppressive treatments, acute rejection episodes, CMV and BK infections, VUR grade in the renal graft, DMSA results, treatment type and its outcomes, and the renal graft functions of four patients who underwent kidney transplantation at Tepecik Training and Research Hospital between 2008 and 2016 and for whom VUR was determined via voiding cystourethrography (VCUG) due to recurrent urinary tract infections, were evaluated. Results: All of four cases were female. Their mean transplantation age was 8.7 years (5-16). High grade (Grade 4) VUR was determined in the graft kidney in all but one. DMSA included multiple scar foci apart from one case having low grade VUR. Cases were primarily treated endoscopically and then by open surgery. Spontaneous recovery occurred in one case. Graft dysfunction was not observed in any of the cases. Conclusion: VUR is an important risk factor in recurrent urinary tract infections after post-transplantation. A special assessment should be done for the patient in the presence of VUR and conservative and surgical treatments should be executed together. It should be remembered that VUR can be spontaneously regressed by the bladder capacity increasing treatments and prophylaxis.

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