Chapter 5 Linear Quantitative Structure–Activity Relationships for the Interaction of Small Molecules with Human Cytochrome P450 Isoenzymes

Annual Reports in Computational Chemistry ◽

10.1016/s1574-1400(07)03005-8 ◽

2007 ◽

pp. 63-81 ◽

Author(s):

Thomas Fox ◽

Jan M. Kriegl

Keyword(s):

Cytochrome P450 ◽

Small Molecules ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Human Cytochrome ◽

Quantitative Structure Activity Relationships

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Quantitative structure–activity relationships (QSARs) within the cytochrome P450 system: QSARs describing substrate binding, inhibition and induction of P450s

Inflammopharmacology ◽

10.1163/156856003321547112 ◽

2003 ◽

Vol 11 (1) ◽

pp. 43-73 ◽

Author(s):

David F. V. Lewis

Keyword(s):

Cytochrome P450 ◽

Substrate Binding ◽

Quantitative Structure ◽

Cytochrome P450 System ◽

Structure Activity Relationships ◽

Structure Activity ◽

Binding Inhibition ◽

Quantitative Structure Activity Relationships

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Theoretical quantitative structure–activity relationships of flavone ligands interacting with cytochrome P450 1A1 and 1A2 isozymes

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2005.04.066 ◽

2005 ◽

Vol 13 (14) ◽

pp. 4366-4374 ◽

Author(s):

F. Iori ◽

R. da Fonseca ◽

M. João Ramos ◽

M.C. Menziani

Keyword(s):

Cytochrome P450 ◽

Quantitative Structure ◽

Cytochrome P450 1A1 ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Quantitative Structure-Activity Relationships (QSAR) Study of Flavonoid Derivatives for Inhibition of Cytochrome P450 1A2

Quantitative Structure-Activity Relationships ◽

10.1002/1521-3838(200006)19:3<257::aid-qsar257>3.0.co;2-2 ◽

2000 ◽

Vol 19 (3) ◽

pp. 257-263 ◽

Author(s):

Taesung Moon ◽

Myung Hwan Chi ◽

Dong-Hyun Kim ◽

Chang No Yoon ◽

Young-Sang Choi

Keyword(s):

Cytochrome P450 ◽

Quantitative Structure ◽

Cytochrome P450 1A2 ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Molecular Modelling of Lanosterol 14α-Demethylase (CYPSl) fromSaccharomyces Cerevisiaevia Homology with CYP102, a Unique Bacterial Cytochrome P450 Isoform: Quantitative Structure-Activity Relationships (QSARs) within two Related Series of Antifungal Azole Derivatives

Journal of Enzyme Inhibition ◽

10.3109/14756369909030315 ◽

1999 ◽

Vol 14 (3) ◽

pp. 175-192 ◽

Author(s):

David F.V. Lewis ◽

Alan Wiseman ◽

Mike H. Tarbit

Keyword(s):

Cytochrome P450 ◽

Molecular Modelling ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Related Series ◽

Quantitative Structure Activity Relationships

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QUANTITATIVE STRUCTURE–ACTIVITY RELATIONSHIPS FOR PREDICTING METABOLISM AND MODELING CYTOCHROME P450 ENZYME ACTIVITIES

Environmental Toxicology and Chemistry ◽

10.1897/01-480 ◽

2003 ◽

Vol 22 (8) ◽

pp. 1894 ◽

Author(s):

Anthony Long ◽

John D. Walker

Keyword(s):

Cytochrome P450 ◽

Enzyme Activities ◽

Cytochrome P450 Enzyme ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

P450 Enzyme ◽

Quantitative Structure Activity Relationships

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Quantitative Structure-Activity Relationships of Potential Antimalarial Drugs Active Against Chloroquine-Resistant Plasmodium Falciparum

Planta Medica ◽

10.1055/s-2008-1075144 ◽

2008 ◽

Vol 74 (03) ◽

Author(s):

SJ Hocart ◽

H Liu ◽

D De ◽

FM Krogstad ◽

DJ Krogstad

Keyword(s):

Plasmodium Falciparum ◽

Antimalarial Drugs ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Parabolic Quantitative Structure–Activity Relationships and Photodynamic Therapy: Application of a Three-Compartment Model with Clearance to the In Vivo Quantitative Structure–Activity Relationships of a Congeneric Series of Pyropheophorbide Derivatives Used as Photosensitizers for Photodynamic Therapy

Photochemistry and Photobiology ◽

10.1562/0031-8655(1999)070<0781:pqsrap>2.3.co;2 ◽

1999 ◽

Vol 70 (5) ◽

pp. 781 ◽

Author(s):

W. R. Potter ◽

B. W. Henderson ◽

D. A. Bellnier ◽

R. K. Pandey ◽

L. A. Vaughan ◽

...

Keyword(s):

Photodynamic Therapy ◽

Compartment Model ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Three Compartment Model ◽

Quantitative Structure Activity Relationships

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Binding Affinity of Triphenyl Acrylonitriles to Estrogen Receptors: Quantitative Structure-Activity Relationships

Folia Medica ◽

10.2478/v10153-010-0005-2 ◽

2010 ◽

Vol 52 (3) ◽

Author(s):

Sorana Bolboacă ◽

Monica Marta ◽

Lorentz Jäntschi

Keyword(s):

Estrogen Receptors ◽

Binding Affinity ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships

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Quantitative Structure-Activity Relationships for Cellular Uptake of Surface-Modified Nanoparticles

Combinatorial Chemistry & High Throughput Screening ◽

10.2174/1386207318666150306105525 ◽

2015 ◽

Vol 18 (4) ◽

pp. 365-375 ◽

Author(s):

Rong Liu ◽

Robert Rallo ◽

Muhammad Bilal ◽

Yoram Cohen

Keyword(s):

Cellular Uptake ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Surface Modified ◽

Surface Modified Nanoparticles

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Investigation of the Structural Requirement for Blocking the Human CCR5 Chemokine Receptor. An Insight from Quantitative Structure Activity Relationships Study

Letters in Drug Design & Discovery ◽

10.2174/157018009787582615 ◽

2009 ◽

Vol 6 (2) ◽

pp. 114-124 ◽

Author(s):

Nigus Dessalew

Keyword(s):

Chemokine Receptor ◽

Quantitative Structure ◽

Structural Requirement ◽

Ccr5 Chemokine Receptor ◽

Structure Activity Relationships ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

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