Use of thin film freezing to enable drug delivery: a review

2009 ◽  
Vol 19 (2) ◽  
pp. 89-98 ◽  
Author(s):  
K.A. Overhoff ◽  
K.P. Johnston ◽  
J. Tam ◽  
J. Engstrom ◽  
R.O. Williams
Keyword(s):  
Thin Film ◽  
Drug Delivery ◽  
Thin Film Freezing

scholarly journals Niclosamide Inhalation Powder Made by Thin-Film Freezing: Multi-dose tolerability and exposure in Rats and Pharmacokinetics in Hamsters

2021 ◽  
pp. 120701
Author(s):  
Miguel O. Jara ◽  
Zachary N. Warnken ◽  
Sawittree Sahakijpijarn ◽  
Chaeho Moon ◽  
Esther Y. Maier ◽  
...  
Keyword(s):  
Thin Film ◽  
Inhalation Powder ◽  
Thin Film Freezing

Towards nanoporous polymer thin film-based drug delivery systems

2009 ◽  
Vol 517 (5) ◽  
pp. 1794-1798 ◽  
Author(s):  
Wei Yan ◽  
Vincent K.S. Hsiao ◽  
Yue Bing Zheng ◽  
Yasir M. Shariff ◽  
Tieyu Gao ◽  
...  
Keyword(s):  
Thin Film ◽  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Polymer Thin Film

scholarly journals In Vitro and In Vivo Performance of Dry Powder Inhalation Formulations: Comparison of Particles Prepared by Thin Film Freezing and Micronization

2014 ◽  
Vol 15 (4) ◽  
pp. 981-993 ◽  
Author(s):  
Yi-Bo Wang ◽  
Alan B. Watts ◽  
Jay I. Peters ◽  
Sha Liu ◽  
Ayesha Batra ◽  
...  
Keyword(s):  
Thin Film ◽  
Dry Powder Inhalation ◽  
Dry Powder ◽  
Thin Film Freezing

Dry powder insufflation of crystalline and amorphous voriconazole formulations produced by thin film freezing to mice

2012 ◽  
Vol 81 (3) ◽  
pp. 600-608 ◽  
Author(s):  
Nicole A. Beinborn ◽  
Ju Du ◽  
Nathan P. Wiederhold ◽  
Hugh D.C. Smyth ◽  
Robert O. Williams
Keyword(s):  
Thin Film ◽  
Dry Powder ◽  
Thin Film Freezing

scholarly journals The Development of Thin-film Freezing and Its Application to Improve Delivery of Biologics as Dry Powder Aerosols

2022 ◽  
Author(s):  
Stephanie Hufnagel ◽  
Sawittree Sahakijpijarn ◽  
Chaeho Moon ◽  
Zhengrong Cui ◽  
Robert O. Williams III
Keyword(s):  
Thin Film ◽  
Dry Powder ◽  
Dry Powder Aerosols ◽  
Powder Aerosols ◽  
Thin Film Freezing

scholarly journals Oral dissolving film: present and future aspects

2018 ◽  
Vol 8 (6) ◽  
pp. 373-377
Author(s):  
Prabhjot Kaur ◽  
Rajeev Garg
Keyword(s):  
Thin Film ◽  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Innovative Drug ◽  
Patient Acceptability ◽  
First Pass Metabolism ◽  
First Pass ◽  
Recent Trends ◽  
Pass Metabolism

Over the past few decades, tendency toward innovative drug delivery systems has almightily increased attempts to ensure efficacy, safety and patient acceptability. As discovery and development of new chemical agents is a complex, expensive and time consuming process, so recent trends are shifting toward designing and developing innovative drug delivery systems for existing drugs. Orally fast dissolving film is the kind of drug delivery system which when placed in the oral cavity, disintegrate or dissolve within a few seconds without the intake of water. Oral fast dissolving film is relatively new dosage form in which thin film is prepared using hydrophilic polymers, which rapidly disintegrate or dissolves on tongue or in the buccal cavity It is an alternative platform for molecules that undergoes high first pass metabolism. The method of preparation for oral dissolving film. Solvent casting, Semisolid casting, Hot melt extrusion, Solid dispersion extrusion, Rolling The current evaluation gives an account of different formulations methods of preparation and quality control of the fast dissolving oral thin film. Keyword:  First pass metabolism, Tensile strength,  Fast Dissolving Oral Film etc.

Formation of Stable Submicron Protein Particles by Thin Film Freezing

2008 ◽  
Vol 25 (6) ◽  
pp. 1334-1346 ◽  
Author(s):  
Joshua D. Engstrom ◽  
Edwina S. Lai ◽  
Baltej S. Ludher ◽  
Bo Chen ◽  
Thomas E. Milner ◽  
...  
Keyword(s):  
Thin Film ◽  
Protein Particles ◽  
Thin Film Freezing
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