Optimization of Process Parameters for Enhanced Degradation of Methylene Blue by Trough Ultrasonic

Due to the complex quality and the large discharge of printing and dyeing wastewater, it will pollute the environment and affect human health. Therefore, how to use efficient and inexpensive treatment methods to treat printing and dyeing wastewater has become an urgent problem to be solved. At present, most printing and dyeing wastewater contains methylene blue pollutants. Based on the previous research in this article, the process conditions for the enhanced degradation of methylene blue by trough ultrasound are optimized. Orthogonal test results show that the optimal process parameter for the degradation of methylene blue by trough ultrasonic is pH 12.70, and the initial With a concentration of 10.00mg/L and an ultrasonic power of 200W, under the above optimal process conditions, the degradation rate of methylene blue is 77.95%; Ultrasound improves the rapid degradation of methylene blue through mechanisms such as cavitation, thermal and mechanical effects. This process can be used for the industrial degradation of methylene blue. The application provides a research basis.

Synergistic advanced oxidation process for enhanced degradation of organic pollutants in spent sulfuric acid over recoverable apricot shell-derived biochar catalyst

A synergistic advanced oxidation process was constructed to degrade the organic pollutants in spent sulfuric acid with apricot shell-derived biochar as the catalyst. It realized the effect of treating waste with waste.

The auxin-inducible degron 2 (AID2) system enables controlled protein knockdown during embryogenesis and development in Caenorhabditis elegans

Targeted protein degradation using the auxin-inducible degron (AID) system is garnering attention in the research field of Caenorhabditis elegans, because of the rapid and efficient target depletion it affords, which can be controlled by treating the animals with the phytohormone auxin. However, the current AID system has drawbacks, i.e., leaky degradation in the absence of auxin and the requirement for high auxin doses. Furthermore, it is challenging to deplete degron-fused proteins in embryos because of their eggshell, which blocks auxin permeability. Here, we apply an improved AID2 system utilizing AtTIR1(F79G) and 5-Ph-IAA to C. elegans and demonstrated that it confers better degradation control vs. the previous system by suppressing leaky degradation and inducing sharp degradation using 1300-fold lower 5-Ph-IAA doses. We successfully degraded the endogenous histone H2A.Z protein fused to an mAID degron and disclosed its requirement in larval growth and reproduction, regardless of the presence of maternally inherited H2A.Z molecules. Moreover, we developed an eggshell-permeable 5-Ph-IAA analogue, 5-Ph-IAA-AM, that affords an enhanced degradation in laid embryos. Our improved system will contribute to the disclosure of the roles of proteins in C. elegans, in particular those that are involved in embryogenesis and development, through temporally controlled protein degradation.