Pharmacokinetics and correlation between in vitro release and in vivo absorption of bio-adhesive pellets of panax notoginseng saponins

2017 ◽  
Vol 15 (2) ◽  
pp. 142-151 ◽  
Author(s):  
Ying LI ◽  
Yun ZHANG ◽  
Chun-Yan ZHU
Keyword(s):  
In Vitro Release ◽  
Panax Notoginseng ◽  
Panax Notoginseng Saponins ◽  
In Vivo Absorption ◽  
Vitro Release

Medicament Release from Ointment Bases: III. Ibuprofen: In Vitro Release and In-Vivo Absorption in Rabbits

1986 ◽  
Vol 12 (14) ◽  
pp. 2521-2540 ◽  
Author(s):  
A. Muktadir ◽  
A. Babar ◽  
A. J. Cutie ◽  
F. M. Plakogiannis
Keyword(s):  
In Vitro Release ◽  
In Vivo Absorption ◽  
Vitro Release

Diadermatic Dose Forms Of Testosterone: In-Vitro Release Studies and in-Vivo Absorption In A Human Male

1989 ◽  
Vol 15 (9) ◽  
pp. 1405-1422
Author(s):  
A. Babar ◽  
R. A. Khaleque ◽  
A. J. Cutie ◽  
F. M. Plakogiannis
Keyword(s):  
In Vitro Release ◽  
Human Male ◽  
Release Studies ◽  
In Vivo Absorption ◽  
Vitro Release

Correlation of ‘in vitro’ release and ‘in vivo’ absorption characteristics of rifampicin from ethylcellulose coated nonpareil beads

2001 ◽  
Vol 230 (1-2) ◽  
pp. 1-9 ◽  
Author(s):  
B Sreenivasa Rao ◽  
A Seshasayana ◽  
S.V Pardha Saradhi ◽  
N Ravi Kumar ◽  
Cheruvu P.S Narayan ◽  
...  
Keyword(s):  
In Vitro Release ◽  
In Vivo Absorption ◽  
Vitro Release ◽  
Absorption Characteristics

In vitro release and in vivo absorption in beagle dogs of meloxicam from Eudragit® FS 30 D-coated pellets

2006 ◽  
Vol 322 (1-2) ◽  
pp. 104-112 ◽  
Author(s):  
Chunsheng Gao ◽  
Jian Huang ◽  
Yan Jiao ◽  
Li Shan ◽  
Yan Liu ◽  
...  
Keyword(s):  
In Vitro Release ◽  
Beagle Dogs ◽  
In Vivo Absorption ◽  
Vitro Release

Formulation and Evaluation of Pimozide Buccal Mucoadhesive Patches

1970 ◽  
Vol 2 (4) ◽  
pp. 739-747
Author(s):  
Biswajit Basu ◽  
Kevin Garala ◽  
Thimmasetty J
Keyword(s):  
Release Kinetics ◽  
In Vitro Release ◽  
In Vivo Studies ◽  
Poly Vinyl Alcohol ◽  
Content Uniformity ◽  
In Vivo Absorption ◽  
Systemic Drug Delivery ◽  
Vitro Release

Within the oral mucosal cavity, the buccal region offers an attractive route of administration for systemic drug delivery. Pimozide patches were prepared using HPMC (15 & 47 cPs), carbopol 934, poly vinyl alcohol, and poly vinyl pyrolidone. FTIR and UV spectroscopic methods revealed that there is no interaction between pimozide and polymers. The patches were evaluated for their thickness uniformity, folding endurance, weight uniformity, content uniformity, swelling behaviour, tensile strength, and surface pH. In vitro release studies of pimozide-loaded patches in phosphate buffer (pH, 6.6) exhibited drug release in the range of 55.32 % to 97.49 % in 60 min. Data of in vitro release from patches were fit in to different equations and kinetic models to explain release kinetics. The models used were zero and first-order equations, Hixon-Crowell, Higuchi and Korsmeyer-Peppas models. In vivo absorption of pimozide from all the patches ranged from 47.96 % to 83.42 % in 60 min in human volunteers. In vivo studies in rabbits showed 85.97% of drug absorption from HPMC-15 cPs patch in 60 min. Good correlation among in vitro release and in vivo absorption of pimozide was observed

Medicament Release from Ointment Bases: IV. Piroxicam: In-vitro Release and In-Vivo Absorption in Rabbits

1987 ◽  
Vol 13 (8) ◽  
pp. 1371-1397 ◽  
Author(s):  
P. Dallas ◽  
M. B. Sideman ◽  
J. Polak ◽  
F. M. Plakogiannis
Keyword(s):  
In Vitro Release ◽  
In Vivo Absorption ◽  
Vitro Release

Evaluation of in Vitro Release Rate and in Vivo Absorption Characteristics of Four Metoprolol Tartrate Immediate-Release Tablet Formulations

1997 ◽  
Vol 2 (1) ◽  
pp. 11-24 ◽  
Author(s):  
Gurvinder Singh Rekhi ◽  
Natalie D. Eddington ◽  
Michael J. Fossler ◽  
Paul Schwartz ◽  
Lawrence J. Lesko ◽  
...  
Keyword(s):  
Release Rate ◽  
In Vitro Release ◽  
Immediate Release ◽  
Metoprolol Tartrate ◽  
In Vivo Absorption ◽  
Tablet Formulations ◽  
Vitro Release ◽  
Absorption Characteristics
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