Computational paradigms for analyzing genetic interaction networks

2015 ◽  
pp. 12-35
Author(s):  
Carles Pons ◽  
Michael Costanzo ◽  
Charles Boone ◽  
Chad L. Myers
Keyword(s):  
Genetic Interaction ◽  
Interaction Networks

scholarly journals Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes

2008 ◽  
Vol 105 (43) ◽  
pp. 16653-16658 ◽  
Author(s):  
S. J. Dixon ◽  
Y. Fedyshyn ◽  
J. L. Y. Koh ◽  
T. S. K. Prasad ◽  
C. Chahwan ◽  
...  
Keyword(s):  
Genetic Interaction ◽  
Interaction Networks ◽  
Synthetic Lethal

scholarly journals A multilevel layout algorithm for visualizing physical and genetic interaction networks, with emphasis on their modular organization

2012 ◽  
Vol 5 (1) ◽  
Author(s):  
Johannes Tuikkala ◽  
Heidi Vähämaa ◽  
Pekka Salmela ◽  
Olli S Nevalainen ◽  
Tero Aittokallio
Keyword(s):  
Genetic Interaction ◽  
Interaction Networks ◽  
Modular Organization ◽  
Layout Algorithm

scholarly journals mSphere of Influence: Evolutionary Strategies To Sensitize Drug-Resistant Pathogens

mSphere ◽  
2019 ◽  
Vol 4 (3) ◽  
Author(s):  
Rebecca S. Shapiro
Keyword(s):  
Drug Resistance ◽  
Antimicrobial Resistance ◽  
Genetic Interaction ◽  
Interaction Networks ◽  
Evolutionary Strategies ◽  
Drug Resistant ◽  
Bacterial Evolution ◽  
Resistance Development ◽  
Collateral Sensitivity ◽  
Link Type

ABSTRACTRebecca S. Shapiro studies antimicrobial resistance and genetic interaction networks. In this mSphere of Influence article, she reflects on how the papers “Bacterial evolution of antibiotic hypersensitivity” by Lázár et al. (V. Lázár, G. Pal Singh, R. Spohn, I. Nagy, et al., Mol Syst Biol 9:700, 2013,https://doi.org/10.1038/msb.2013.57) and “Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development” by L. Imamovic and M. O. A. Sommer (Sci Transl Med 5:204ra132, 2013,https://doi.org/10.1126/scitranslmed.3006609) impacted her thinking about multigene interaction effects on drug resistance.

scholarly journals Analysis of Genetic Interaction Networks Shows That Alternatively Spliced Genes Are Highly Versatile

PLoS ONE ◽  
2013 ◽  
Vol 8 (2) ◽  
pp. e55671 ◽  
Author(s):  
David Talavera ◽  
Ritika Sheoran ◽  
Simon C. Lovell
Keyword(s):  
Genetic Interaction ◽  
Interaction Networks ◽  
Alternatively Spliced

scholarly journals Antagonism of Chemical Genetic Interaction Networks Resensitize MRSA to β-Lactam Antibiotics

2011 ◽  
Vol 18 (11) ◽  
pp. 1379-1389 ◽  
Author(s):  
Sang Ho Lee ◽  
Lisa Wang Jarantow ◽  
Hao Wang ◽  
Susan Sillaots ◽  
Henry Cheng ◽  
...  
Keyword(s):  
Genetic Interaction ◽  
Interaction Networks ◽  
Chemical Genetic

Design, execution, and analysis of CRISPR–Cas9-based deletions and genetic interaction networks in the fungal pathogen Candida albicans

2019 ◽  
Vol 14 (3) ◽  
pp. 955-975 ◽  
Author(s):  
Viola Halder ◽  
Caroline B. M. Porter ◽  
Alejandro Chavez ◽  
Rebecca S. Shapiro
Keyword(s):  
Candida Albicans ◽  
Fungal Pathogen ◽  
Genetic Interaction ◽  
Interaction Networks
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