scholarly journals Serologic evidence of the postoperative persistence of hydatid cysts in man

1975 ◽  
Vol 75 (3) ◽  
pp. 333-340 ◽  
Author(s):  
R. M. Matossian ◽  
G. F. Araj

SUMMARYThe sensitivity of the haemagglutination, complement-fixation and indirect fluorescent antibody tests in the diagnosis of primary and recurrent hydatid disease is presented. In the first, diagnostic titres were obtained in 90%, 80% and 96% of 50 patients with hepatic and 64%, 60% and 68% of 25 patients with pulmonary cysts, respectively. In the postoperative study of 62 patients, elevated titres of HA, CF and IFA antibodies in 30 led to the presumptive diagnosis of recurrent disease, confirmed later by radiological and surgical follow-ups. In the 32 others the proportion of positive reactors was 29%, 6% and 28% in HA, CF and IFA tests. These patients had no detectable cysts. This indicates that in post-operative patients a negative CF test may be of a better prognostic value in indicating absence of cysts than the HA and IFA tests.

2017 ◽  
Vol 29 (5) ◽  
pp. 612-621 ◽  
Author(s):  
Camila C. Abreu ◽  
Erin E. Edwards ◽  
John F. Edwards ◽  
Philippa M. Gibbons ◽  
Jeann Leal de Araújo ◽  
...  

Clostridium chauvoei causes blackleg in cattle. The disease has been reported worldwide, and although it can be prevented by vaccination, sporadic cases and occasional outbreaks still occur. We describe a case of blackleg in a 2-y-old, pregnant Gyr cow with in utero transmission to the fetus. The cow had characteristic gross and microscopic lesions of blackleg including widespread necrohemorrhagic and emphysematous skeletal and myocardial myositis, and fibrinous pericarditis. Her uterus contained a near-term, markedly emphysematous fetus with skeletal muscle and myocardial lesions similar to those seen in the dam. Histopathology of dam and fetal tissues revealed numerous gram-positive bacilli, many of them with sub-terminal spores, in multiple tissues. These bacilli were identified as C. chauvoei by immunohistochemistry. Anaerobic culture and fluorescent antibody tests performed on skeletal muscle from both the dam and fetus were positive for C. chauvoei, confirming a diagnosis of blackleg. Blackleg is a so-called endogenous infection, and the currently accepted pathogenesis involves ingestion of spores that are transported to muscle tissues where they lie dormant until anaerobiosis prompts germination. Germinating bacteria are histotoxic, producing severe, local necrosis and ultimately lethal toxemia. This model, however, has not been confirmed experimentally and also fails to explain some cases of the disease. A presumptive diagnosis of blackleg is based on clinical, gross, and histologic findings. Diagnostic confirmation necessitates the detection of C. chauvoei by culture, PCR, or immunodetection methods.


1955 ◽  
Vol 90 (1) ◽  
pp. 118-122 ◽  
Author(s):  
S. M. Cohen ◽  
I. Gordon ◽  
F. Rapp ◽  
J. C. Macaulay ◽  
S. M. Buckley

1972 ◽  
Vol 13 (1) ◽  
pp. 77-82 ◽  
Author(s):  
M. Goldman ◽  
E. Pipano ◽  
A.S. Rosenberg

2005 ◽  
Vol 33 (2) ◽  
pp. 215-221 ◽  
Author(s):  
S Sebit ◽  
H Tunc ◽  
R Gorur ◽  
T Isitmangil ◽  
A Yildizhan ◽  
...  

Cases of intrathoracic extrapulmonary hydatid cysts are very rare. We identified 13 patients with intrathoracic extra-pulmonary hydatid cysts in our clinic over 12 years. Four patients had extra-pulmonary cysts only; nine patients had both intrapulmonary and extrapulmonary cysts. Cysts were identified in the pleural space, extrapleural region, diaphragm and chest wall. Thoracotomy was used in all patients, and extrapulmonary lesions were removed by cyst extirpation from surrounding tissue or by pericystectomy. In one patient with chest wall involvement, partial rib resections were performed because of rib destruction. In two patients with liver cysts passing through the diaphragm to the thorax, the diaphragm was cut, cysts on the liver roof were removed and then the diaphragm was repaired. There was no mortality, morbidity, or disease recurrence during the post-operative period in any of the 13 patients. We conclude that these rare cases give a new insight into hydatid cyst pathophysiology.


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