scholarly journals An outbreak of aseptic meningitis associated with a previously unrecognized virus

1961 ◽  
Vol 59 (2) ◽  
pp. 181-189 ◽  
Author(s):  
I. B. R. Duncan
Keyword(s):  
Aseptic Meningitis ◽  
Kidney Tissue ◽  
Monkey Kidney ◽  
Human Thyroid ◽  
Tissue Cultures ◽  
Human Amnion ◽  
Echo Virus

In 1959, 69 cases of aseptic meningitis were admitted to various hospitals in Scotland—all apparently due to a Hitherto unrecognized virus. This agent had the characteristics of an ECHO virus but differed from the 28 ECHO viruses at present recognized. Seventy-five strains of the virus were isolated, and human thyroid and human amnion tissue cultures proved much superior to monkey kidney tissue cultures for its isolation.

scholarly journals Aseptic meningitis due to infection with ECHO virus (Type 9)

1957 ◽  
Vol 55 (4) ◽  
pp. 464-474 ◽  
Author(s):  
D. M. McLean ◽  
D. Cameron
Keyword(s):  
Cerebrospinal Fluid ◽  
Aseptic Meningitis ◽  
Technical Assistance ◽  
Total Population ◽  
Severe Headache ◽  
Monkey Kidney ◽  
Neck Stiffness ◽  
Human Amnion ◽  
Group Type ◽  
Echo Virus

Eleven cases of aseptic meningitis occurred in a Cambridgeshire village between 17 October and 11 November 1955. The syndrome consisted of severe headache, backache, vomiting, fever and neck stiffness together with lymphocytes and frequently some granulocytes in the cerebrospinal fluid. Principally, it affected persons aged between 10 and 30 years. Out of a total population twenty-three at risk, seventeen were infected and eight became ill. A further three contacts who were living in Cambridge became ill.Identical strains of virus were isolated from the faeces of two patients by inoculation of trypsin-dispersed human amnion cells and from the faeces of another two patients by inoculation of monkey kidney cultures. Bourn virus, which belonged to the ECHO group, Type 9, multiplied readily and produced cytopathogenic effects in human amnion and monkey kidney cultures, but it was not cytopathogenic in HeLa cell cultures. These investigations strongly suggest that Bourn virus caused the epidemic.We wish to thank Dr M. G. P. Stoker for his advice and criticism and Mrs B. M. Cook for technical assistance.We are indebted to Dr J. O'H. Tobin and Dr F. K. Sanders for advice on certain technical procedures.It is a pleasure to acknowledge the assistance given by many colleagues and friends, including Dr D. I. Annear, Miss D. K. Bell, Mrs D. Ditchburn, Dr R. M. Fry, Dr D. Gairdner, Dr J. E. Power, Dr D. Simpson, Dr P. Tyzer and Dr P. J. Wormald.

Infection of Monkey Kidney Tissue Cultures with Virus-Like Agents.

1955 ◽  
Vol 88 (1) ◽  
pp. 8-16 ◽  
Author(s):  
R. Rustigian ◽  
P. Johnston ◽  
H. Reihart
Keyword(s):  
Kidney Tissue ◽  
Monkey Kidney ◽  
Tissue Cultures

Serial Propagation of Adenoviruses (APG) in Monkey Kidney Tissue Cultures

1956 ◽  
Vol 92 (4) ◽  
pp. 667-669 ◽  
Author(s):  
J. W. Hartley ◽  
R. J. Huebner ◽  
W. P. Rowe
Keyword(s):  
Kidney Tissue ◽  
Monkey Kidney ◽  
Tissue Cultures ◽  
Serial Propagation

Echo Virus Type 23 (Williamson) in Monkey Kidney Tissue Culture

Nature ◽  
1962 ◽  
Vol 195 (4846) ◽  
pp. 1127-1128
Author(s):  
AKINYELE FABIYI ◽  
LELIA M. OLSEN ◽  
JEAN WESTON ◽  
HERBERT A. WENNER
Keyword(s):  
Tissue Culture ◽  
Virus Type ◽  
Kidney Tissue ◽  
Monkey Kidney ◽  
Echo Virus

Primary Isolation of Influenza A, B, and G Viruses in Monkey Kidney Tissue Cultures.

1955 ◽  
Vol 89 (2) ◽  
pp. 308-311 ◽  
Author(s):  
K. K. Takemoto ◽  
R. K. Lynt ◽  
W. P. Rowe ◽  
R. J. Huebner ◽  
J. A. Bell ◽  
...  
Keyword(s):  
Influenza A ◽  
Kidney Tissue ◽  
Monkey Kidney ◽  
Tissue Cultures ◽  
Primary Isolation
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