Hearing impairment and facial palsy as initial signs of Wegener's granulomatosis

1980 ◽  
Vol 94 (6) ◽  
pp. 649-657 ◽  
Author(s):  
I. H. Calonius ◽  
C. K. Christensen
Keyword(s):  
Facial Nerve ◽  
Hearing Impairment ◽  
Otitis Media ◽  
Wegener’S Granulomatosis ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Wegener's Granulomatosis ◽  
The Other ◽  
Treatment Resistant ◽  
Serous Otitis Media

SummaryIn two patients with Wegener's granulomatosis, treatment-resistant serous otitis media was followed by unilateral facial nerve palsy. Later both patients developed uraemia due to extracapillary glomerulonephritis. In one of them, who was treated with prednisone and cyclophosphamide, renal function improved, while in the other patient it remained impaired. Both patients suffered lasting hearing impairment in spite of general improvement during the course of the disease. The facial nerve palsy improved slightly in one, while no improvement was seen in the other.The possibility of Wegener's granulomatosis or other autoimmune collagen diseases should be considered in cases of treatment-resistant serous otitis media. Early diagnosis and treatment can possibly save the patient from the lifethreatening consequences of these diseases.

Fatal course of Wegener's granulomatosis with bilateral otomastoiditis and bilateral facial nerve palsy

2008 ◽  
Vol 138 (6) ◽  
pp. 799-800 ◽  
Author(s):  
F. Preuss Simon ◽  
Markus Stenner ◽  
Dirk Beutner ◽  
Matthias Laudes ◽  
Jens Peter Klussmann
Keyword(s):  
Facial Nerve ◽  
Wegener’S Granulomatosis ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Wegener's Granulomatosis ◽  
Fatal Course

scholarly journals A Case of Wegener’s Granulomatosis Presenting with Unilateral Facial Nerve Palsy

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Roy Ujjawal ◽  
Pan Koushik ◽  
Panwar Ajay ◽  
Chakrabarti Subrata
Keyword(s):  
Facial Nerve ◽  
Wegener’S Granulomatosis ◽  
Nerve Palsy ◽  
Acute Inflammation ◽  
Granulomatosis With Polyangiitis ◽  
Medical Literature ◽  
Facial Nerve Palsy ◽  
Renal Involvement ◽  
Wegener's Granulomatosis ◽  
Classical Triad

Wegener’s granulomatosis or granulomatosis with polyangiitis is a necrotizing vasculitis affecting both arterioles and venules. The disease is characterized by the classical triad involving acute inflammation of the upper and lower respiratory tracts with renal involvement. However, the disease pathology can affect any organ system. This case presents Wegener’s granulomatosis presenting with facial nerve palsy as the first manifestation of the disease, which is rarely reported in medical literature.

Wegener's granulomatosis presenting with bilateral facial nerve palsy

2001 ◽  
Vol 258 (4) ◽  
pp. 198-202 ◽  
Author(s):  
A. C. Nikolaou ◽  
Konstantinos C. Vlachtsis ◽  
Michalis A. Daniilidis ◽  
Dimitrios G. Petridis ◽  
Ioannis C. Daniilidis
Keyword(s):  
Facial Nerve ◽  
Wegener’S Granulomatosis ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Wegener's Granulomatosis

Early diagnosis of Wegener's granulomatosis presenting with facial nerve palsy

1996 ◽  
Vol 110 (5) ◽  
pp. 459-461 ◽  
Author(s):  
J. D. Hern ◽  
L. J. Hollis ◽  
G. Mochloulis ◽  
P. Q. Montgomery ◽  
N. S. Tolley
Keyword(s):  
Early Diagnosis ◽  
Facial Nerve ◽  
Wegener’S Granulomatosis ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Disease Process ◽  
Wegener's Granulomatosis ◽  
Granuloma Formation ◽  
Diagnostic Process ◽  
Middle Ear Surgery

AbstractWegener's granulomatosis is a multi-system disease characterized by granuloma formation and a necrotizing vasculitis. It classically presents with involvement of the upper and lower respiratory and renal systems. However locoregional disease is common and may include otological manifestations. Facial nerve palsy has been reported during the course of the disease process but it is extremely rare for it to be the presenting feature. Previously reported cases have involved a protracted diagnostic process including exploratory tympanotomy, mastoidectomy and facial nerve decompression. We report a case of Wegener's granulomatosis which presented with a facial nerve palsy. An early diagnosis was achieved by measurement of the erythrocyte sedimentation rate (ESR), followed by serological assay of cytoplasmic anti-neutrophil cytoplasmic antibody (cANCA). Histological examination of nasal mucosal biopsies confirmed granuloma formation consistent with a diagnosis of Wegener's granulomatosis. This allowed early treatment with immunosuppressive therapy and avoided unnecessary and potentially hazardous middle ear surgery.

Otologic Wegener's Granulomatosis with Facial Nerve Palsy

1998 ◽  
Vol 107 (7) ◽  
pp. 555-559 ◽  
Author(s):  
Paul Dagum ◽  
Joseph B. Roberson
Keyword(s):  
Facial Nerve ◽  
Wegener’S Granulomatosis ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Correct Diagnosis ◽  
Cranial Nerves ◽  
Serum Levels ◽  
Antineutrophil Cytoplasmic Antibody ◽  
Wegener's Granulomatosis ◽  
Facial Nerve Decompression

Wegener's granulomatosis, characterized by necrotizing granulomas and vasculitis of the respiratory tract and kidney, frequently first presents with otologic symptoms. We report a case of primary otologic Wegener's granulomatosis in a patient who presented with symptoms of acute otomastoiditis and associated facial nerve palsy. The patient subsequently developed neuropathies of various cranial nerves. The patient underwent urgent mastoidectomy with facial nerve decompression. Nonspecific inflammatory disease of the mastoid mucosa delayed the correct diagnosis of Wegener's granulomatosis, which was confirmed by an elevated level of cytoplasmic-pattern antineutrophil cytoplasmic antibody (cANCA). We contrast the specificity of middle ear mucosal disease and cANCA serum levels in the diagnosis of Wegener's granulomatosis.

Facial nerve palsy secondary to acute otitis media

1989 ◽  
Vol 89 (2) ◽  
pp. 207-211
Author(s):  
Patrick E. Henderson ◽  
Samuel C. Baldone
Keyword(s):  
Facial Nerve ◽  
Otitis Media ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Acute Otitis Media

Acute otitis media with facial nerve palsy

2020 ◽  
Vol 154 (12) ◽  
pp. 526
Author(s):  
Kalaiarasi Raja ◽  
Satvinder Singh Bakshi
Keyword(s):  
Facial Nerve ◽  
Otitis Media ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Acute Otitis Media

Bilateral facial nerve palsy following secretory otitis media

1989 ◽  
Vol 103 (7) ◽  
pp. 685-685 ◽  
Author(s):  
D. J. Premachandra ◽  
G. Radcliffe
Keyword(s):  
Facial Nerve ◽  
Otitis Media ◽  
World Literature ◽  
Nerve Palsy ◽  
Facial Nerve Palsy ◽  
Secretory Otitis Media ◽  
Suppurative Otitis Media ◽  
The World

AbstractFacial nerve palsy is a known complication of acute suppurative otitis media. Cases of facial nerve palsy following secretory otitis media have not been reported in the world literature. We report a case of bilateral facial nerve palsy following secretory otitis media.

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