The effects of D and L Isomers of menthol upon nasal sensation of airflow

1988 ◽  
Vol 102 (6) ◽  
pp. 506-508 ◽  
Author(s):  
R. Eccles ◽  
D. H. Griffiths ◽  
C. G. Newton ◽  
N. S. Tolley
Keyword(s):  
Sensory Nerve ◽  
Nerve Endings ◽  
Nasal Airway ◽  
Nasal Airflow ◽  
Airway Patency ◽  
Sensory Nerve Endings ◽  
Before And After ◽  
Subjective Measurements

AbstractObjective and subjective measurements of nasal airflow were made before and after inhalation of Vanilla, D-Menthol and L-Menthol separately. Despite the fact that the menthol isomers were mirror images of one another, only L-Menthol produced the sensation of increased nasal airway patency. No objective change in resistance was found after inhaling either D-Menthol, L-Menthol or the vanilla control. These findings demonstrate that L-Menthol exerts a specific action upon nasal sensory nerve endings, which are responsible for the subjective appreciation of nasal airflow.

scholarly journals The effect of decongestion on nasal airway patency and airflow

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Qiwei Xiao ◽  
Alister J. Bates ◽  
Raul Cetto ◽  
Denis J. Doorly
Keyword(s):  
Nasal Airway ◽  
Nasal Resistance ◽  
Nasal Airflow ◽  
Cross Sectional ◽  
Airway Patency ◽  
Flow Rates ◽  
High Resolution Mri ◽  
Nasal Anatomy ◽  
Before And After ◽  
Flow Through

AbstractNasal decongestant reduces blood flow to the nasal turbinates, reducing tissue volume and increasing nasal airway patency. This study maps the changes in nasal anatomy and measures how these changes affect nasal resistance, flow partitioning between superior and inferior cavity, flow patterns and wall shear stress. High-resolution MRI was applied to capture nasal anatomy in 10 healthy subjects before and after application of a topical decongestant. Computational fluid dynamics simulated nasal airflow at steady inspiratory flow rates of 15 L.min$$^{-1}$$ - 1 and 30 L.min$$^{-1}$$ - 1 . The results show decongestion mainly increases the cross-sectional area in the turbinate region and SAVR is reduced (median approximately 40$$\%$$ % reduction) in middle and lower parts of the cavity. Decongestion reduces nasal resistance by 50$$\%$$ % on average, while in the posterior cavity, nasal resistance decreases by a median factor of approximately 3 after decongestion. We also find decongestant regularises nasal airflow and alters the partitioning of flow, significantly decreasing flow through the superior portions of the nasal cavity. By comparing nasal anatomies and airflow in their normal state with that when pharmacologically decongested, this study provides data for a broad range of anatomy and airflow conditions, which may help characterize the extent of nasal variability.

Ultrastructure of sensory nerve endings in monkey (Macaca fascicularis) knee joint capsule

1984 ◽  
Vol 2 (2) ◽  
pp. 169-176 ◽  
Author(s):  
Zdenek Halata ◽  
Marie A. Badalamente ◽  
Roger Dee ◽  
Michael Propper
Keyword(s):  
Knee Joint ◽  
Macaca Fascicularis ◽  
Sensory Nerve ◽  
Joint Capsule ◽  
Nerve Endings ◽  
Sensory Nerve Endings

59 Immunohistochemical study of sensory nerve endings in the coracoacromial arch

1998 ◽  
Vol 7 (3) ◽  
pp. 338
Author(s):  
M Tamai ◽  
M Kurokawa ◽  
S Okajima ◽  
N Takenaka ◽  
Y Takubo ◽  
...  
Keyword(s):  
Immunohistochemical Study ◽  
Sensory Nerve ◽  
Nerve Endings ◽  
Sensory Nerve Endings ◽  
Coracoacromial Arch

scholarly journals Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis-causing mutations

2015 ◽  
Vol 523 (17) ◽  
pp. Spc1-Spc1 ◽  
Author(s):  
Sydney K. Vaughan ◽  
Zachary Kemp ◽  
Theo Hatzipetros ◽  
Fernando Vieira ◽  
Gregorio Valdez
Keyword(s):  
Amyotrophic Lateral Sclerosis ◽  
Sensory Nerve ◽  
Nerve Endings ◽  
Sensory Nerve Endings ◽  
Lateral Sclerosis
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