Olfactory neural tumours—the role of external beam radiotherapy

1996 ◽  
Vol 110 (11) ◽  
pp. 1012-1016 ◽  
Author(s):  
N. J. Slevin ◽  
C. J. R. Irwin ◽  
S. S. Banerjee ◽  
N. K. Gupta ◽  
W. T. Farrington

AbstractOlfactory neuroblastoma is an uncommon tumour arising in the nasal cavity or paranasal sinuses. We report the management of nine cases treated with external beam radiotherapy subsequent to sureery, either attempted definitive removal or biopsy only. Recent refinements in pathologicalevaluation of these tumours are discussed. Seven cases were deemed classical olfactory neuroblastoma whilst two were classified as neuroendocrine carcinoma. The clinical features, radirap technique and variable natural history are presented. Seven of eight patients treatecall were controlled locally, with a minimumfollow-up of two years. Three patients developedcervica lymph node disease and three patients died of systemic metastatic disease. Suggestios are made as to which patients should have en-bloc resection rather than definitive radiotherapy.

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Cicilia Marcella ◽  
Rui Hua Shi ◽  
Shakeel Sarwar

Aims. To review the clinical presentation, diagnosis, assessment of risk of malignancy, and recent advances in management (mainly focusing on the role of endoscopic resection) of gastrointestinal stromal tumors (GISTs) in upper GI.Method. We searched Embase, Web of science, and PubMed databases from 1993 to 2018 by using the following keywords: “gastrointestinal stromal tumors,” “GIST,” “treatment,” and “diagnosis.” Additional papers were searched manually from references of the related articles.Findings. The improvement of endoscopic techniques in treating upper gastrointestinal subepithelial tumors especially gastrointestinal tumors has reduced the need for invasive surgery in patients unfit for surgery. Many studies have concluded that modified endoscopic treatments are effective and safe. These treatments permit minimal tissue resection, better dissection control, and high rates of en bloc resection with an acceptable rate of complications.


2021 ◽  
Vol 14 (2) ◽  
pp. e239466
Author(s):  
Sofia Isabel Tamesa Manlubatan ◽  
Marc Paul Jose Lopez ◽  
Carlo Martin Hilomen Garcia ◽  
Czar Louie Lopez Gaston

This is a case of a 50-year-old woman diagnosed with recurrent cervical adenocarcinoma presenting with chronic and persistent low back pain. She underwent myomectomy for myoma uteri 8 years prior. Histopathology report revealed cervical cancer. She underwent chemotherapy, brachytherapy and external beam radiotherapy. All surveillance work-up, over the years, were negative until she was found to have a solitary recurrent lesion in the right iliopsoas muscle on CT scan. A multidisciplinary team of surgeons collaborated to perform wide excision of pelvic recurrence en bloc right internal hemipelvectomy, right hemicolectomy en bloc resection of external iliac artery and vein, external ilio-iliac artery interposition graft and external iliac vein–common femoral vein bypass. Final histopathologic results showed adenocarcinoma with endometrioid features with associated poorly differentiated high-grade carcinoma involving the iliopsoas, cecum and terminal ileum. Two months postoperatively, the patient is ambulating with minimal assistance.


2007 ◽  
Vol 11 (4) ◽  
pp. 346-349 ◽  
Author(s):  
P. V. Tsarkov ◽  
Y. V. Belov ◽  
O. G. Skipenko ◽  
Z. S. Zavenyan ◽  
Y. N. Makeev ◽  
...  

2010 ◽  
Vol 72 (4) ◽  
pp. 831-835 ◽  
Author(s):  
Brian G. Turner ◽  
Denise W. Gee ◽  
Sevdenur Cizginer ◽  
Min-Chan Kim ◽  
Mari Mino-Kenudson ◽  
...  

2019 ◽  
Vol 1 (1) ◽  
Author(s):  
Sarah E Tevis ◽  
Kelly K Hunt ◽  
Mark W Clemens

Abstract Guidelines published by the National Comprehensive Cancer Network state that standard of care treatment for the majority of patients with breast implant-associated anaplastic large-cell lymphoma (BIA-ALCL) is surgical resection. This cancer is generally indolent, and if confined to the capsule, curative treatment is usually surgery alone. An en bloc resection involves a total capsulectomy, explantation, complete excision of associated masses, and excision of any involved lymph node(s). Patients with surgical control of disease have favorable long-term overall and event-free survival. Oncologic principles should be applied when resecting BIA-ALCL, and a complete oncologic resection is essential to cure patients of the disease. Incomplete resections, partial capsulectomies, and positive margins are all associated with high rates of disease recurrence and have potential for progression of the disease. Routine sentinel lymph node biopsy is unnecessary and full axillary lymph node dissection is rarely indicated except in cases of proven involvement of multiple nodes. Lymphoma oncology consultation and disease staging by imaging is performed prior to surgery. Importantly, en bloc resection is indicated only for an established diagnosis of BIA-ALCL, and is not recommended for merely suspicious or prophylactic surgeries. The purpose of this article was to demonstrate a stepwise approach to surgical ablation of BIA-ALCL with an emphasis on oncologic considerations critical to disease prognosis.


2020 ◽  
Vol 30 (1) ◽  
pp. 119-125
Author(s):  
Munechika Tsumura ◽  
Seiichiro Makihara ◽  
Kazuhiro Omura ◽  
Tomoyuki Naito ◽  
Junya Matsumoto ◽  
...  

Author(s):  
Baki Erdem ◽  
Lale Karakış ◽  
Osman Asıcıoğlu ◽  
Hüseyin Kıyak ◽  
Gülseren Yılmaz

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