Miller Fisher syndrome: a diagnosis not to be missed

2007 ◽  
Vol 122 (1) ◽  
pp. 82-85 ◽  
Author(s):  
S J Davis ◽  
R Salib ◽  
H Buchan ◽  
E Nilssen
Keyword(s):  
Early Diagnosis ◽  
Campylobacter Jejuni ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Favourable Prognosis ◽  
Mode Of Presentation ◽  
Nasal Regurgitation ◽  
Management Issues

AbstractWe report a case of Miller Fisher syndrome presenting in an ENT setting. The referral was made on the basis of worsening nasal regurgitation following Campylobacter jejuni enteritis. The aim of this report is not to add to the recorded instances of Miller Fisher syndrome, but to help raise the level of its awareness amongst otolaryngologists. Emphasis is placed on the mode of presentation and management issues, as early diagnosis is crucial and confers a favourable prognosis. In that respect, we consider this case noteworthy and instructive.

scholarly journals Serum antibodies against gangliosides and Campylobacter jejuni lipopolysaccharides in Miller Fisher syndrome.

1997 ◽  
Vol 65 (10) ◽  
pp. 4038-4042 ◽  
Author(s):  
A Neisser ◽  
H Bernheimer ◽  
T Berger ◽  
A P Moran ◽  
B Schwerer
Keyword(s):  
Campylobacter Jejuni ◽  
Miller Fisher Syndrome ◽  
Serum Antibodies ◽  
Fisher Syndrome

scholarly journals Humoral immune response against Campylobacter jejuni lipopolysaccharides in Guillain-Barré and Miller Fisher syndrome

1997 ◽  
Vol 79 (1) ◽  
pp. 62-68 ◽  
Author(s):  
B.C Jacobs ◽  
H.Ph Endtz ◽  
F.G.A van der Meché ◽  
M.P Hazenberg ◽  
M.A de Klerk ◽  
...  
Keyword(s):  
Immune Response ◽  
Campylobacter Jejuni ◽  
Humoral Immune Response ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Humoral Immune ◽  
Guillain Barré

Anti-GQ1B IGG antibodies can cross-react with campylobacter jejuni from patients with miller fisher syndrome

1994 ◽  
Vol 54 (1-2) ◽  
pp. 170 ◽  
Author(s):  
B.C. Jacobs ◽  
H.P. Endtz ◽  
F.G.A. van der Meché ◽  
M. Hazenberg ◽  
H.A.M. Achtereekte ◽  
...  
Keyword(s):  
Campylobacter Jejuni ◽  
Miller Fisher Syndrome ◽  
Igg Antibodies ◽  
Fisher Syndrome

scholarly journals Structure of Campylobacter jejuni Lipopolysaccharides Determines Antiganglioside Specificity and Clinical Features of Guillain-Barré and Miller Fisher Patients

2002 ◽  
Vol 70 (3) ◽  
pp. 1202-1208 ◽  
Author(s):  
C. W. Ang ◽  
J. D. Laman ◽  
H. J. Willison ◽  
E. R. Wagner ◽  
H. P. Endtz ◽  
...  
Keyword(s):  
Risk Factor ◽  
Antibody Response ◽  
Campylobacter Jejuni ◽  
Clinical Features ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Antibody Reactivity ◽  
Strong Antibody Response ◽  
Almost All

ABSTRACT Ganglioside mimicry in the lipopolysaccharide (LPS) fraction of Campylobacter jejuni isolated from Guillain-Barré syndrome (GBS) and Miller Fisher syndrome (MFS) patients was compared with isolates from patients with an uncomplicated enteritis. The antibody response to C. jejuni LPS and gangliosides in neuropathy patients and controls was compared as well. LPS from GBS and MFS-associated isolates more frequently contained ganglioside-like epitopes compared to control isolates. Almost all neuropathy patients showed a strong antibody response against LPS and multiple gangliosides in contrast to enteritis patients. Isolates from GBS patients more frequently had a GM1-like epitope than isolates from MFS patients. GQ1b-like epitopes were present in all MFS-associated isolates and was associated with anti-GQ1b antibody reactivity and the presence of oculomotor symptoms. These results demonstrate that the expression of ganglioside mimics is a risk factor for the development of post-Campylobacter neuropathy. This study provides additional evidence for the hypothesis that the LPS fraction determines the antiganglioside specificity and clinical features in post-Campylobacter neuropathy patients.

scholarly journals Cross-Reactive Antibodies against Gangliosides and Campylobacter jejuni Lipopolysaccharides in Patients with Guillaln-Barre or Miller Fisher Syndrome

1997 ◽  
Vol 175 (3) ◽  
pp. 729-733 ◽  
Author(s):  
B. C. Jacobs ◽  
M. P. Hazenberg ◽  
P. A. van Doorn ◽  
H. P. Endtz ◽  
F. G. A. van der Meche
Keyword(s):  
Campylobacter Jejuni ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome

scholarly journals Miller-Fisher syndrome associated with Campylobacter jejuni bearing lipopolysaccharide molecules that mimic human ganglioside GD3.

1996 ◽  
Vol 64 (8) ◽  
pp. 2945-2949 ◽  
Author(s):  
S Salloway ◽  
L A Mermel ◽  
M Seamans ◽  
G O Aspinall ◽  
J E Nam Shin ◽  
...  
Keyword(s):  
Campylobacter Jejuni ◽  
Miller Fisher Syndrome ◽  
Fisher Syndrome ◽  
Ganglioside Gd3
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