Osteoradionecrosis of tympanic bone: reconstruction of outer ear canal with pedicled skin flap, combined with hyperbaric oxygen therapy, in five patients

2009 ◽  
Vol 123 (10) ◽  
pp. 1114-1119 ◽  
Author(s):  
M Metselaar ◽  
A G Dumans ◽  
M P C van der Huls ◽  
W Sterk ◽  
L Feenstra

AbstractObjective:To evaluate the results of one-stage surgical repair of the meatal skin defect in patients with long-lasting osteoradionecrosis of the outer ear canal, using a postauricular, inferiorly pedicled skin flap. All patients were also treated with hyperbaric oxygen both pre- and post-operatively.Methods:A prospective study evaluating the results of a one-stage surgical procedure to repair the meatal skin defect in five patients with osteoradionecrosis of the outer ear canal. All patients were treated with hyperbaric oxygen both pre- and post-operatively.Results:In four of the five patients, intact canal skin was achieved after surgery and hyperbaric oxygen therapy. One patient needed a second operation to cover a small remaining area of bare bone. In one patient, wound healing was unsatisfactory and an area of bare bone remained.Conclusion:In cases of osteoradionecrosis of the outer ear canal, the skin defect can be repaired with an inferiorly pedicled skin flap. Although not yet scientifically proven, the peri-operative application of hyperbaric oxygen may be of additional value to improve wound healing in areas of compromised tissue.

2014 ◽  
Vol 133 (2) ◽  
pp. 208e-215e ◽  
Author(s):  
Phillip B. Dauwe ◽  
Benson J. Pulikkottil ◽  
Lawrence Lavery ◽  
James M. Stuzin ◽  
Rod J. Rohrich

2009 ◽  
Vol 106 (3) ◽  
pp. 988-995 ◽  
Author(s):  
Stephen R. Thom

The goal of this review is to outline advances addressing the role that reactive species of oxygen and nitrogen play in therapeutic mechanisms of hyperbaric oxygen. The review will be organized around major categories of problems or processes where controlled clinical trials have demonstrated clinical efficacy for hyperbaric oxygen therapy. Reactive species are now recognized to play a major role in cell signal transduction cascades, and the discussion will focus on how hyperbaric oxygen acts through these pathways to mediate wound healing and ameliorate postischemic and inflammatory injuries.


2018 ◽  
Vol 47 (6) ◽  
pp. 827-836 ◽  
Author(s):  
Christian R. Latimer ◽  
Cassie N. Lux ◽  
Sarah Roberts ◽  
Marti G. Drum ◽  
Cheryl Braswell ◽  
...  

2004 ◽  
Vol 16 (5) ◽  
pp. 475-478 ◽  
Author(s):  
Senol Yildiz ◽  
Haldun Uluutku ◽  
Alp Gunay ◽  
I2smail Yildirim ◽  
??ukru Yildirim ◽  
...  

2016 ◽  
Vol 2 (1) ◽  
pp. 49 ◽  
Author(s):  
Prihartini Widiyanti

Hyperbaric oxygen therapy (HBOT) is the inhalation of 100 percent oxygen inside a hyperbaric chamber that is pressurized to greater than 1 atmosphere (atm). HBOT causes both mechanical and physiologic effects by inducing a state of increased pressure and hyperoxia. HBOT is typically administered at 1 to 3 atm. While the duration of an HBOT session is typically 90 to 120 minutes, the duration, frequency, and cumulative number of sessions have not been standardized. HBO has been use widely in treating gangrene diabetic, stroke, osteomyelitis and accelerating wound healing. The use of HBO in infectious disease is wide, so the mechanism of hyperbaric oxygen in infectious disease should be well-understand. This understanding could bring the proper and wise management of infectious disease and to prevent the side effect of each therapy.


2017 ◽  
Vol 06 (10) ◽  
pp. 250-254 ◽  
Author(s):  
Fassil B. Mesfin ◽  
Matthew R. Burton ◽  
Ruben A. Ngnitewe Massa ◽  
Jeffery S. Litt

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