Multifocal extraparotid Warthin's tumours mimicking metastatic squamous cell carcinoma of the upper neck

2015 ◽  
Vol 129 (5) ◽  
pp. 513-516 ◽  
Author(s):  
S G Mistry ◽  
D Gouldesbrough ◽  
C Bem
Keyword(s):  
Squamous Cell Carcinoma ◽  
Parotid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Frozen Section ◽  
Radical Neck Dissection ◽  
Radical Resection ◽  
Unknown Primary ◽  
Male Smoker ◽  
Metastatic Squamous Cell Carcinoma

AbstractBackground:Warthin's tumours can show features of pseudo-neoplasia. They do not usually cause problems for diagnosis and management when present within the parotid gland. However, extraparotid Warthin's tumours that are associated with pseudo-neoplasia upon cytological analysis can mimic metastatic malignant disease. The case of a patient presenting with multifocal extraparotid Warthin's tumours is described.Case report:A 57-year-old male smoker presented with rapidly growing upper neck lumps. Fine needle aspiration cytology, magnetic resonance imaging and positron emission tomography findings were compatible with metastatic squamous cell carcinoma secondary to either an unknown primary upper aerodigestive or a parotid malignancy. The patient subsequently underwent total conservative parotidectomy and modified radical neck dissection. Final histology findings revealed multifocal benign Warthin's tumours with four extraparotid components.Conclusion:Warthin's tumours may present outside the parotid gland, present with multifocal lesions and mimic metastatic disease. Frozen section examination prior to radical resection should be considered to guide management.

Metastatic squamous cell carcinoma to cervical lymph nodes from unknown primary mucosal sites

Head & Neck ◽  
1994 ◽  
Vol 16 (1) ◽  
pp. 58-63 ◽  
Author(s):  
Cam Nguyen ◽  
George Shenouda ◽  
Martin J. Black ◽  
Te Vuong ◽  
David Donath ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Unknown Primary ◽  
Cervical Lymph Nodes ◽  
Metastatic Squamous Cell Carcinoma

Role of neck dissection in metastatic squamous cell carcinoma to the parotid gland

2016 ◽  
Vol 130 (S4) ◽  
pp. S54-S59 ◽  
Author(s):  
S W Park ◽  
T Eade ◽  
L Pang ◽  
A Wignall ◽  
D Veivers
Keyword(s):  
Squamous Cell Carcinoma ◽  
Parotid Gland ◽  
Cell Carcinoma ◽  
Neck Dissection ◽  
Squamous Cell ◽  
Consecutive Series ◽  
Radiological Evidence ◽  
Neck Disease ◽  
Positron Emission ◽  
Metastatic Squamous Cell Carcinoma

AbstractObjective:To investigate the rate of occult neck disease in patients with metastatic squamous cell carcinoma to the parotid gland following parotidectomy and neck dissection.Methods:A consecutive series of patients treated between 2000 and 2014 for metastatic squamous cell carcinoma to the parotid were analysed. Patients were included if they had no clinical or radiological evidence of neck disease. Pathology of parotidectomy and neck dissection specimens was reviewed. Other variables analysed included patient immune status, surgery type, complications, use of positron emission tomography scanning and treatment with radiotherapy.Results:Sixty-five patients had no clinical or radiological evidence of neck disease initially. Forty-six patients (70.8 per cent) underwent neck dissection. Occult neck disease was only found in 8 of the 46 patients (17.3 per cent). Occult neck disease was found more often in those with immunocompromise (5.7 vs 38.5 per cent, p = 0.003). Patients who were immunocompromised had a significantly worse disease-specific survival rate at five years (0 vs 92 per cent, p = 0.0001).Conclusion:Occult neck disease was seen in 17.3 per cent of patients and immunosuppression was a significant predictor for this.

Cisplatin and 5-Fluorouracil for Metastatic Squamous Cell Carcinoma from Unknown Primary

1995 ◽  
Vol 13 (3) ◽  
pp. 263-266 ◽  
Author(s):  
Tawfiq Khansur ◽  
Cecilia Allred ◽  
Diana Little ◽  
Vinod Anand
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Unknown Primary ◽  
Metastatic Squamous Cell Carcinoma

scholarly journals Facial Nerve Preservation In Treatment Of Primary Parotid Squamous Cell Carcinoma: A Case Report

2021 ◽  
Author(s):  
Chunming Huang ◽  
Mingliang Cheng ◽  
Xiaojuan Luo ◽  
Xiaoping Zhao
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Parotid Gland ◽  
Facial Nerve ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Radical Resection ◽  
Nerve Preservation ◽  
Facial Nerve Preservation ◽  
Total Parotidectomy

Abstract BackgroundPrimary squamous cell carcinoma rarely occurs in parotid gland. Partial, superficial or total parotidectomy as well as radical resection is performed based on patients’ conditions. For patients with symptoms of facial nerve weakness or dysfunction, facial nerve preservation is considered justifiably, whereas groundlessly if the malignancy is asymptomatic. We hereby reported a case of symptomatic primary parotid squamous cell carcinoma performed with total parotidectomy and facial nerve preservation.Case summaryWith the complaint of an asymptomatic mass in right parotid gland for five years and it grew aggressively and pricked recent months, a 46-year-old man visited the local hospital two week ago. A biopsy was performed and squamous cell carcinoma in right parotid gland was diagnosed. He was subsequently referred to Tongji hospital in Wuhan, China. Physical exam revealed a scar in the right parotid gland and impaired function of right facial nerves. An immoveable mass was touched in lower and posterior pole of right parotid gland. The mass was about 2.1*3.1 cm without clear boundary, and moderate pain was observed. No obvious enlarged lymph node was touched in right submandibular region and neck. Magnetic resonance imaging revealed a 1.6*2.4 cm nodular located in a diffuse suspicious mass in right parotid gland. Radical resection of the malignancy was rejected due to the inevitable facioplegia. Considering the short history of tumor aggressive behaviors, unique anatomical structure of parotid gland and absent sign of lymph node metastasis, total parotidectomy with facial nerve preservation and elective right neck dissection were performed. Finial pathological examination confirmed squamous cell carcinoma of right parotid gland. Post-operation radiotherapy was scheduled in the following month. Restoration of facial nerve function was observed in two months later, absent local recurrence and distant metastasis was observed in the three years’ follow-up.Conclusion Primary parotid squamous cell carcinoma is rarely observed in clinical and facial nerve sacrifice requires great attention in treatment. Based on carefully evaluation of patients’ conditions before treatment, individualized treatment is crucial for improvement of patients’ quality of life while completely dissection of the malignancy.

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