Bronchoscopy in panendoscopy: review and assessment

2015 ◽  
Vol 129 (12) ◽  
pp. 1220-1223 ◽  
Author(s):  
A Shahangian ◽  
E J Damrose

AbstractObjective:To determine the utility of bronchoscopy to identify synchronous primaries in head and neck cancer patients.Study design:Case series with chart review.Method:The charts of all patients undergoing bronchoscopy between January 2008 and December 2013 were reviewed. Only those undergoing bronchoscopy as part of panendoscopy for head and neck cancer were included. Operative reports, pathology reports and discharge summaries were reviewed for operative findings, complications and length of hospital stay.Results:A total of 404 charts were reviewed and 168 were included in the study. No synchronous primaries were identified. Bronchoscopy changed clinical management in one patient. There were no complications from bronchoscopy.Conclusion:Bronchoscopy is a safe and well-tolerated procedure commonly performed in the investigation of head and neck cancer patients, but it adds little additional useful clinical information. Routine performance of bronchoscopy in this setting should be weighed against its added costs, and tailored to the individual patient.

Author(s):  
AC Prado-Ribeiro ◽  
AC Luiz ◽  
MA. Montezuma ◽  
MP Mak ◽  
AR Santos-Silva ◽  
...  

1995 ◽  
Vol 14 ◽  
pp. 56
Author(s):  
M.A.E. van Bokhorst-de van der Schueren ◽  
J.J. Quak ◽  
H.P. Sauerwein ◽  
R.I.C. Wesdorp ◽  
G.B. Snow ◽  
...  

2008 ◽  
Vol 139 (2_suppl) ◽  
pp. P35-P36
Author(s):  
Mrinal Supriya ◽  
Louise Santangeli ◽  
Muhammad Shakeel ◽  
Kim Ah-See

Objective Can we control MRSA incidence in head and neck cancer patients by 1) Active surveillance cultures of patients fulfilling Society for Healthcare Epidemiology of America (SHEA) & Scottish Infection Standards and Strategy (SISS) guideline? 2) Cohorting these patients? 3) Restricted Health Care Workers (HCW) access? Methods Prospective case series: July 2007–January 2008. 26 preoperative head and neck cancer patients had a questionnaire filled in to identify known predictors for MRSA as suggested by SISS Group. Intervention: Preoperative nasal swabs, cohorting away from other cases, restricted access. MRSA incidence compared to that over the preceding year(Jan 2006-Jan 2007). Results 26 eligible patients. None of them had known risk factors for MRSA. 17 patients had swabs taken pre-admission. All screened patients were non-carriers of MRSA in their nose and none of them developed MRSA infection during hospital stay. Of remaining 9 patients swabbed after admission, 3 developed MRSA during hospital stay. The incidence of MRSA was 11.5% (3/26) during study period, compared to 28.5% (24/84) the year before implementing these interventions. Conclusions Head and neck cancer patients do not have increased risk factors for MRSA colonization and their active surveillance cultures are unlikely to influence MRSA incidence. Cohorting these patients with restricted HCW access decreased the MRSA rate at our centre.


Metabolites ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 60 ◽  
Author(s):  
Karol Jelonek ◽  
Aleksandra Krzywon ◽  
Patrycja Jablonska ◽  
Ewa M. Slominska ◽  
Ryszard T. Smolenski ◽  
...  

Anticancer treatment induces systemic molecular changes that could be detected at the level of biofluids. Understanding how human metabolism is influenced by these treatments is crucial to predict the individual response and adjust personalized therapies. Here, we aimed to compare profiles of metabolites in serum of head and neck cancer patients treated with concurrent chemo-radiotherapy, radiotherapy alone, or induction chemotherapy. Serum samples were analyzed by a targeted quantitative approach using combined direct flow injection and liquid chromatography coupled to tandem mass spectrometry, which allowed simultaneous quantification of 149 metabolites. There were 45 metabolites whose levels were significantly changed between pretreatment and within- or post-treatment serum samples, including 38 phospholipids. Concurrent chemo-radiotherapy induced faster and stronger effects than radiotherapy alone. On the other hand, chemotherapy alone did not result in significant changes. The decreased level of total phospholipids was the most apparent effect observed during the first step of the treatment. This corresponded to the loss of patients’ body mass, yet no correlation between both parameters was observed for individual patients. We concluded that different molecular changes were measured at the level of serum metabolome in response to different treatment modalities.


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